A Study of the Safety and Tolerability of ABBV-621 in Participants With Previously-Treated Solid Tumors and Hematologic Malignancies
Public ClinicalTrials.gov record NCT03082209. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Phase 1, First-In-Human Study of TRAIL Receptor Agonist ABBV-621 in Subjects With Previously-Treated Solid Tumors and Hematologic Malignancies
Study identification
- NCT ID
- NCT03082209
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 153 participants
Conditions and interventions
Conditions
Interventions
- ABBV-621 Drug
- Bevacizumab Drug
- FOLFIRI Drug
- Venetoclax Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 19, 2017
- Primary completion
- Jan 20, 2022
- Completion
- Jan 20, 2022
- Last update posted
- Dec 8, 2022
2017 – 2022
United States locations
- U.S. sites
- 10
- U.S. states
- 7
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Yale University /ID# 158029 | New Haven | Connecticut | 06510 | — |
| The University of Chicago Medical Center /ID# 158030 | Chicago | Illinois | 60637-1443 | — |
| Ingalls Memorial Hosp /ID# 171221 | Harvey | Illinois | 60426 | — |
| Univ Michigan Med Ctr /ID# 207134 | Ann Arbor | Michigan | 48109 | — |
| Rhode Island Hospital /ID# 171157 | Providence | Rhode Island | 02903 | — |
| Vanderbilt University Medical Center /ID# 215000 | Nashville | Tennessee | 37232-0011 | — |
| MD Anderson Cancer Center /ID# 202187 | Houston | Texas | 77030 | — |
| Millennium Oncology /ID# 214981 | Houston | Texas | 77090-1243 | — |
| South Texas Accelerated Research Therapeutics /ID# 160574 | San Antonio | Texas | 78229 | — |
| Medical College of Wisconsin /ID# 171152 | Milwaukee | Wisconsin | 53226-3522 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03082209, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 8, 2022 · Synced May 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03082209 live on ClinicalTrials.gov.