Study of Irinotecan Liposome Injection (ONIVYDE®) in Patients With Small Cell Lung Cancer
Public ClinicalTrials.gov record NCT03088813. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
RESILIENT: A Randomized, Open Label Phase 3 Study of Irinotecan Liposome Injection (ONIVYDE®) Versus Topotecan in Patients With Small Cell Lung Cancer Who Have Progressed on or After Platinum-based First-Line Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A randomized, open label phase 3 study of irinotecan liposome injection (ONIVYDE®) versus topotecan in patients with small cell lung cancer who have progressed on or after platinum-based first-line therapy The study was conducted in two parts: 1. Dose determination of irinotecan liposome injection 2. A randomized, efficacy study of irinotecan liposome injection versus topotecan
Study identification
- NCT ID
- NCT03088813
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 491 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 25, 2018 (Actual)
- Primary completion
- Feb 8, 2022 (Actual)
- Completion
- Jul 27, 2023 (Actual)
- Last update posted
- Feb 19, 2025
2018 – 2023
United States locations
- U.S. sites
- 22
- U.S. states
- 13
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| National Jewish Health | Denver | Colorado | 80206 | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | — |
| Florida Cancer Specialists (South Region) | Fort Myers | Florida | 33916 | — |
| Florida Cancer Specialists | St. Petersburg | Florida | 33705 | — |
| Northwest Georgia Oncology Centers | Marietta | Georgia | 30060 | — |
| Cancer Treatment Centers of America-Georgia | Newnan | Georgia | 30265 | — |
| Illinois Cancer Care, PC | Peoria | Illinois | 61615 | — |
| Southern Maine Health Care | Biddeford | Maine | 04005 | — |
| University of Maryland Medical Group | Baltimore | Maryland | 21201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Cancer & Hematology Centers of Western Michigan | Grand Rapids | Michigan | 49503 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48219 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| North Shore Hematology Oncology Associates, PC | East Setauket | New York | 11733 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Tri County Hematology & Oncology Associates, Inc | Massillon | Ohio | 44646 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Charleston Hematology Oncology Associates, PA | Charleston | South Carolina | 29414 | — |
| Greenville Hospital System University Medical Center | Greenville | South Carolina | 29605 | — |
| Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| MultiCare Health System Institute for Research and Innovation | Spokane | Washington | 99204 | — |
| Summit Cancer Treatment Center | Spokane | Washington | 99208 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 96 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03088813, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 19, 2025 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03088813 live on ClinicalTrials.gov.