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Completed Phase 3 Interventional Results available

Study of Irinotecan Liposome Injection (ONIVYDE®) in Patients With Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT03088813

Public ClinicalTrials.gov record NCT03088813. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 11:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

RESILIENT: A Randomized, Open Label Phase 3 Study of Irinotecan Liposome Injection (ONIVYDE®) Versus Topotecan in Patients With Small Cell Lung Cancer Who Have Progressed on or After Platinum-based First-Line Therapy

Study identification

NCT ID
NCT03088813
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Ipsen
Industry
Enrollment
491 participants

Conditions and interventions

Interventions

  • Irinotecan liposome injection Drug
  • Topotecan Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 24, 2018
Primary completion
Feb 7, 2022
Completion
Jul 26, 2023
Last update posted
Feb 18, 2025

2018 – 2023

United States locations

U.S. sites
22
U.S. states
13
U.S. cities
20
Facility City State ZIP Site status
National Jewish Health Denver Colorado 80206
Rocky Mountain Cancer Centers Denver Colorado 80218
Florida Cancer Specialists (South Region) Fort Myers Florida 33916
Florida Cancer Specialists St. Petersburg Florida 33705
Northwest Georgia Oncology Centers Marietta Georgia 30060
Cancer Treatment Centers of America-Georgia Newnan Georgia 30265
Illinois Cancer Care, PC Peoria Illinois 61615
Southern Maine Health Care Biddeford Maine 04005
University of Maryland Medical Group Baltimore Maryland 21201
Henry Ford Hospital Detroit Michigan 48202
Cancer & Hematology Centers of Western Michigan Grand Rapids Michigan 49503
Sparrow Regional Cancer Center Lansing Michigan 48219
Roswell Park Cancer Institute Buffalo New York 14263
North Shore Hematology Oncology Associates, PC East Setauket New York 11733
Case Western Reserve University Cleveland Ohio 44106
Tri County Hematology & Oncology Associates, Inc Massillon Ohio 44646
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104
Charleston Hematology Oncology Associates, PA Charleston South Carolina 29414
Greenville Hospital System University Medical Center Greenville South Carolina 29605
Tennessee Oncology Nashville Tennessee 37203
MultiCare Health System Institute for Research and Innovation Spokane Washington 99204
Summit Cancer Treatment Center Spokane Washington 99208

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 96 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03088813, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 18, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03088813 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →