A Study of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment-Naive Adults With Chronic Hepatitis C Virus (HCV) Genotype 1-6 Infection and Compensated Cirrhosis
Public ClinicalTrials.gov record NCT03089944. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single Arm, Open-label Study to Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment Naïve Adults With Chronic Hepatitis C Virus (HCV) Genotype 1-6 Infection and Compensated Cirrhosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 3b, single arm, open-label, multicenter study in treatment naïve adults with chronic HCV infection and compensated cirrhosis to assess the safety of 8 weeks of treatment with glecaprevir/pibrentasvir and to demonstrate the efficacy of the sustained virologic response 12 weeks post dosing (SVR12) rates of 8 weeks of treatment with glecaprevir/pibrentasvir compared to the historical SVR12 rates of 12 weeks of treatment with glecaprevir/pibrentasvir.
Study identification
- NCT ID
- NCT03089944
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 343 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 28, 2017 (Actual)
- Primary completion
- Jul 31, 2019 (Actual)
- Completion
- Nov 8, 2019 (Actual)
- Last update posted
- Jul 13, 2020
2017 – 2019
United States locations
- U.S. sites
- 40
- U.S. states
- 23
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Josephs Hosp and Med Ctr /ID# 162762 | Phoenix | Arizona | 85013 | — |
| Mayo Clinic Arizona /ID# 162314 | Phoenix | Arizona | 85054 | — |
| Liver Wellness Center /ID# 162244 | Little Rock | Arkansas | 72204 | — |
| Felizarta /ID# 162295 | Bakersfield | California | 93301 | — |
| VA Long Beach Healthcare System /ID# 162298 | Long Beach | California | 90822 | — |
| Usc /Id# 162248 | Los Angeles | California | 90033 | — |
| Kaiser Permanente - San Diego (Palm Ave) /ID# 162289 | San Diego | California | 92154 | — |
| Stanford University School of Med /ID# 162209 | Stanford | California | 94305-2200 | — |
| Cedars-Sinai Medical Center - West Hollywood /ID# 162313 | West Hollywood | California | 90048 | — |
| University of Miami /ID# 162210 | Miami | Florida | 33136 | — |
| Triple O Research Institute /ID# 162300 | West Palm Beach | Florida | 33407-3100 | — |
| Piedmont Hospital /ID# 162646 | Atlanta | Georgia | 30309 | — |
| Northwestern University Feinberg School of Medicine /ID# 162208 | Chicago | Illinois | 60611-2927 | — |
| Unity Point Health /ID# 162247 | Des Moines | Iowa | 50309 | — |
| The University of Iowa Hospita /ID# 162214 | Iowa City | Iowa | 52242 | — |
| University of Louisville /ID# 162242 | Louisville | Kentucky | 40202 | — |
| Louisiana Research Ctr. LLC /ID# 162567 | Shreveport | Louisiana | 71105-6800 | — |
| Mercy Medical Center /ID# 162291 | Baltimore | Maryland | 21202 | — |
| Mayo Clinic - Rochester /ID# 162251 | Rochester | Minnesota | 55905-0001 | — |
| Southern Therapy and Advanced Research (STAR) LLC /ID# 162241 | Jackson | Mississippi | 39216 | — |
| CHI Health Alegent Creighton /ID# 162286 | Omaha | Nebraska | 68124 | — |
| Univ Nebraska Med Ctr /ID# 162285 | Omaha | Nebraska | 68198 | — |
| Rnjms /Id# 162213 | Newark | New Jersey | 07103 | — |
| Weill Cornell Medical College /ID# 161051 | New York | New York | 10021 | — |
| Icahn School of Med Mt. Sinai /ID# 162294 | New York | New York | 10029 | — |
| Montefiore Medical Center /ID# 162312 | The Bronx | New York | 10461 | — |
| James J. Peters VA Medical Center /ID# 162644 | The Bronx | New York | 10468 | — |
| Duke University Medical Center /ID# 162299 | Durham | North Carolina | 27710-3000 | — |
| Cumberland Research Assoc /ID# 162212 | Fayetteville | North Carolina | 28304 | — |
| Carolinas Center for Liver Dis /ID# 162569 | Statesville | North Carolina | 28677-3471 | — |
| University Hospitals Cleveland /ID# 162243 | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic /ID# 162570 | Cleveland | Ohio | 44111 | — |
| Osuchs /Id# 162284 | Tulsa | Oklahoma | 74127 | — |
| Lehigh Valley Health Network /ID# 162603 | Allentown | Pennsylvania | 18103 | — |
| Center for Liver Diseases, Oakland /ID# 162568 | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt Univ Med Ctr /ID# 162211 | Nashville | Tennessee | 37232-0011 | — |
| Texas Digestive Disease Consul /ID# 162648 | Dallas | Texas | 75246-1613 | — |
| University of Texas Health /ID# 162288 | Houston | Texas | 77030-1501 | — |
| Virginia Commonwealth Univ /ID# 162215 | Richmond | Virginia | 23219 | — |
| Univ of Wisconsin Hosp/Clinics /ID# 162645 | Madison | Wisconsin | 53792-0001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03089944, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 13, 2020 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03089944 live on ClinicalTrials.gov.