Multi-Center, Randomized, Open-Label Study of G/P +/- RBV for NS5A + SOF Previously Treated GT1 HCV Subjects
Public ClinicalTrials.gov record NCT03092375. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Multi-Center, Randomized, Open-Label, Pragmatic Study of Glecaprevir/Pibrentasvir (G/P) +/- Ribavirin for GT1 Subjects With Chronic Hepatitis C Previously Treated With an NS5A Inhibitor + Sofosbuvir Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study will enroll well-compensated cirrhotic as well as non-cirrhotic subjects treatment experienced with an NS5a Inhibitor + sofosbuvir and will include patients who did not complete the prescribed duration due to adverse event or any reason other than for non/poor compliance. Subjects will be randomized to 12 or 16 weeks of treatment.
Study identification
- NCT ID
- NCT03092375
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 177 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 20, 2017 (Actual)
- Primary completion
- Dec 28, 2018 (Actual)
- Completion
- Feb 6, 2020 (Actual)
- Last update posted
- Feb 26, 2020
2017 – 2020
United States locations
- U.S. sites
- 31
- U.S. states
- 18
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford University | Palo Alto | California | 94305 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Health Research Institute | Washington D.C. | District of Columbia | 20010 | — |
| UF Hepatology Research at CTRB | Gainesville | Florida | 32610 | — |
| UF Health Jacksonville-Gastroenterology Emerson | Jacksonville | Florida | 32207 | — |
| Schiff Center for Liver Diseases/University of Miami | Miami | Florida | 33136 | — |
| Orlando Immunology Center | Orlando | Florida | 32803 | — |
| Atlanta Medical Center | Atlanta | Georgia | 303012 | — |
| Atlanta Gastro Associates | Atlanta | Georgia | 30308 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| The Johns Hopkins Hospital/John G. Bartlett Specialty Practice | Baltimore | Maryland | 21287 | — |
| Digestive Disease Associates, PA | Catonsville | Maryland | 21228 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Michigan | Ann Arbor | Michigan | 48109-5601 | — |
| Univ. of Minnesota Health Clinics and Surgery Center, Inc. | Minneapolis | Minnesota | 55455 | — |
| Southern Therapy and Advanced Research | Jackson | Mississippi | 39216 | — |
| Northwell Health - Sandra Atlaas Bass Center for Liver Diseases | Manhasset | New York | 11030 | — |
| NYU Langone Medical Center | New York | New York | 10016 | — |
| Weill Cornell Medicine, Hepatology | New York | New York | 10021 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| University of Pennsylvania-Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Bon Secours Liver Institute of Virginia | Richmond | Virginia | 23226 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298-0341 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| University of Washington | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03092375, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 26, 2020 · Synced Oct 31, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03092375 live on ClinicalTrials.gov.