ClinicalTrials.gov record
Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
ClinicalTrials.gov ID: NCT03092674
Public ClinicalTrials.gov record NCT03092674. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II/III Trial of "Novel Therapeutics" Versus Azacitidine in Newly Diagnosed Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS), Age 60 or Older LEAP: Less-Intense AML Platform Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase II/III trial studies how well azacitidine with or without nivolumab or midostaurin, or decitabine and cytarabine alone work in treating older patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome. Drugs used in chemotherapy, such as azacitidine, decitabine, and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Midostaurin may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving azacitidine with or without nivolumab or midostaurin, or decitabine and cytarabine alone may kill more cancer cells.
Study identification
- NCT ID
- NCT03092674
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 76 participants
Conditions and interventions
Conditions
Interventions
- Azacitidine Drug
- Cytarabine Drug
- Decitabine Drug
- Laboratory Biomarker Analysis Other
- Midostaurin Drug
- Nivolumab Biological
Drug · Other · Biological
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2, 2018 (Actual)
- Primary completion
- Aug 1, 2023 (Actual)
- Completion
- Jun 26, 2024 (Actual)
- Last update posted
- Jan 16, 2025
2018 – 2024
United States locations
- U.S. sites
- 506
- U.S. states
- 42
- U.S. cities
- 340
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anchorage Associates in Radiation Medicine | Anchorage | Alaska | 98508 | — |
| Alaska Breast Care and Surgery LLC | Anchorage | Alaska | 99508 | — |
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | — |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | — |
| Anchorage Oncology Centre | Anchorage | Alaska | 99508 | — |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| University of Arizona Cancer Center-Orange Grove Campus | Tucson | Arizona | 85704 | — |
| Banner University Medical Center - Tucson | Tucson | Arizona | 85719 | — |
| University of Arizona Cancer Center-North Campus | Tucson | Arizona | 85719 | — |
| CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas | 71913 | — |
| John L McClellan Memorial Veterans Hospital | Little Rock | Arkansas | 72205 | — |
| Kaiser Permanente-Deer Valley Medical Center | Antioch | California | 94531 | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| Kaiser Permanente-Fremont | Fremont | California | 94538 | — |
| Fresno Cancer Center | Fresno | California | 93720 | — |
| Kaiser Permanente-Fresno | Fresno | California | 93720 | — |
| Fremont - Rideout Cancer Center | Marysville | California | 95901 | — |
| Kaiser Permanente-Modesto | Modesto | California | 95356 | — |
| Kaiser Permanente Oakland-Broadway | Oakland | California | 94611 | — |
| Kaiser Permanente-Oakland | Oakland | California | 94611 | — |
| Stanford Cancer Institute Palo Alto | Palo Alto | California | 94304 | — |
| Kaiser Permanente-Rancho Cordova Cancer Center | Rancho Cordova | California | 95670 | — |
| Kaiser Permanente-Redwood City | Redwood City | California | 94063 | — |
| Kaiser Permanente-Richmond | Richmond | California | 94801 | — |
| Rohnert Park Cancer Center | Rohnert Park | California | 94928 | — |
| Kaiser Permanente-Roseville | Roseville | California | 95661 | — |
| The Permanente Medical Group-Roseville Radiation Oncology | Roseville | California | 95678 | — |
| Kaiser Permanente Downtown Commons | Sacramento | California | 95814 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Kaiser Permanente-South Sacramento | Sacramento | California | 95823 | — |
| South Sacramento Cancer Center | Sacramento | California | 95823 | — |
| Kaiser Permanente Sacramento Medical Center | Sacramento | California | 95825 | — |
| Kaiser Permanente-San Francisco | San Francisco | California | 94115 | — |
| Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | 95119 | — |
| Stanford Cancer Center South Bay | San Jose | California | 95124 | — |
| Kaiser Permanente San Leandro | San Leandro | California | 94577 | — |
| Kaiser Permanente-San Rafael | San Rafael | California | 94903 | — |
| Kaiser San Rafael-Gallinas | San Rafael | California | 94903 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051 | — |
| Kaiser Permanente-Santa Rosa | Santa Rosa | California | 95403 | — |
| Kaiser Permanente Cancer Treatment Center | South San Francisco | California | 94080 | — |
| Kaiser Permanente-South San Francisco | South San Francisco | California | 94080 | — |
| Kaiser Permanente-Stockton | Stockton | California | 95210 | — |
| Gene Upshaw Memorial Tahoe Forest Cancer Center | Truckee | California | 96161 | — |
| Kaiser Permanente Medical Center-Vacaville | Vacaville | California | 95688 | — |
| Kaiser Permanente-Vallejo | Vallejo | California | 94589 | — |
| Kaiser Permanente-Walnut Creek | Walnut Creek | California | 94596 | — |
| Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado | 80012 | — |
| Boulder Community Hospital | Boulder | Colorado | 80301 | — |
| Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado | 80304 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | 80907 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| Kaiser Permanente-Franklin | Denver | Colorado | 80205 | — |
| National Jewish Health-Main Campus | Denver | Colorado | 80206 | — |
| The Women's Imaging Center | Denver | Colorado | 80209 | — |
| Porter Adventist Hospital | Denver | Colorado | 80210 | — |
| Colorado Blood Cancer Institute | Denver | Colorado | 80218 | — |
| Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | 80218 | — |
| Rocky Mountain Cancer Centers-Midtown | Denver | Colorado | 80218 | — |
| Saint Joseph Hospital - Cancer Centers of Colorado | Denver | Colorado | 80218 | — |
| Rocky Mountain Cancer Centers-Rose | Denver | Colorado | 80220 | — |
| Western Surgical Care | Denver | Colorado | 80220 | — |
| Mercy Medical Center | Durango | Colorado | 81301 | — |
| Southwest Oncology PC | Durango | Colorado | 81301 | — |
| Mountain Blue Cancer Care Center - Swedish | Englewood | Colorado | 80113 | — |
| Swedish Medical Center | Englewood | Colorado | 80113 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| Mountain Blue Cancer Care Center | Golden | Colorado | 80401 | — |
| National Jewish Health-Western Hematology Oncology | Golden | Colorado | 80401 | — |
| Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | 81501 | — |
| Banner North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| Good Samaritan Hospital - Cancer Centers of Colorado | Lafayette | Colorado | 80026 | — |
| Kaiser Permanente-Rock Creek | Lafayette | Colorado | 80026 | — |
| Rocky Mountain Cancer Centers-Lakewood | Lakewood | Colorado | 80228 | — |
| Saint Anthony Hospital | Lakewood | Colorado | 80228 | — |
| Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado | 80120 | — |
| Littleton Adventist Hospital | Littleton | Colorado | 80122 | — |
| Kaiser Permanente-Lone Tree | Lone Tree | Colorado | 80124 | — |
| Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree | Colorado | 80124 | — |
| Longmont United Hospital | Longmont | Colorado | 80501 | — |
| Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado | 80501 | — |
| Banner McKee Medical Center | Loveland | Colorado | 80539 | — |
| Parker Adventist Hospital | Parker | Colorado | 80138 | — |
| Rocky Mountain Cancer Centers-Parker | Parker | Colorado | 80138 | — |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | — |
| Rocky Mountain Cancer Centers - Pueblo | Pueblo | Colorado | 81008 | — |
| National Jewish Health-Northern Hematology Oncology | Thornton | Colorado | 80260 | — |
| Rocky Mountain Cancer Centers-Thornton | Thornton | Colorado | 80260 | — |
| Intermountain Health Lutheran Hospital | Wheat Ridge | Colorado | 80401 | — |
| Beebe Medical Center | Lewes | Delaware | 19958 | — |
| Delaware Clinical and Laboratory Physicians PA | Newark | Delaware | 19713 | — |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| Beebe Health Campus | Rehoboth Beach | Delaware | 19971 | — |
| TidalHealth Nanticoke / Allen Cancer Center | Seaford | Delaware | 19973 | — |
| Christiana Care Health System-Wilmington Hospital | Wilmington | Delaware | 19801 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224-9980 | — |
| The Watson Clinic | Lakeland | Florida | 33805 | — |
| Sacred Heart Hospital | Pensacola | Florida | 32504 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| John B Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | 96819 | — |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | — |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | — |
| Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | 83605 | — |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | — |
| Walter Knox Memorial Hospital | Emmett | Idaho | 83617 | — |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | — |
| Idaho Urologic Institute-Meridian | Meridian | Idaho | 83642 | — |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | — |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | — |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83687 | — |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | — |
| Kootenai Clinic Cancer Services - Sandpoint | Sandpoint | Idaho | 83864 | — |
| Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | 83301 | — |
| Rush - Copley Medical Center | Aurora | Illinois | 60504 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Memorial Hospital of Carbondale | Carbondale | Illinois | 62902 | — |
| SIH Cancer Institute | Carterville | Illinois | 62918 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| Carle at The Riverfront | Danville | Illinois | 61832 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Western Illinois Cancer Treatment Center | Galesburg | Illinois | 61401 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Edward Hines Jr VA Hospital | Hines | Illinois | 60141 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Marjorie Weinberg Cancer Center at Loyola-Gottlieb | Melrose Park | Illinois | 60160 | — |
| Good Samaritan Regional Health Center | Mount Vernon | Illinois | 62864 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| OSF Saint Francis Radiation Oncology at Pekin | Pekin | Illinois | 61554 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| OSF Saint Francis Radiation Oncology at Peoria Cancer Center | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Valley Radiation Oncology | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| UW Health Carbone Cancer Center Rockford | Rockford | Illinois | 61114 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Southwest Illinois Health Services LLP | Swansea | Illinois | 62226 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| The Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| Rush-Copley Healthcare Center | Yorkville | Illinois | 60560 | — |
| Parkview Hospital Randallia | Fort Wayne | Indiana | 46805 | — |
| Parkview Regional Medical Center | Fort Wayne | Indiana | 46845 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Sidney and Lois Eskenazi Hospital | Indianapolis | Indiana | 46202 | — |
| Reid Health | Richmond | Indiana | 47374 | — |
| Mary Greeley Medical Center | Ames | Iowa | 50010 | — |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | — |
| McFarland Clinic - Boone | Boone | Iowa | 50036 | — |
| Mercy Cancer Center-West Lakes | Clive | Iowa | 50325 | — |
| Mission Cancer and Blood - West Des Moines | Clive | Iowa | 50325 | — |
| Alegent Health Mercy Hospital | Council Bluffs | Iowa | 51503 | — |
| Greater Regional Medical Center | Creston | Iowa | 50801 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Mission Cancer and Blood - Des Moines | Des Moines | Iowa | 50309 | — |
| Broadlawns Medical Center | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| Mission Cancer and Blood - Laurel | Des Moines | Iowa | 50314 | — |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| McFarland Clinic - Trinity Cancer Center | Fort Dodge | Iowa | 50501 | — |
| Trinity Regional Medical Center | Fort Dodge | Iowa | 50501 | — |
| McFarland Clinic - Jefferson | Jefferson | Iowa | 50129 | — |
| McFarland Clinic - Marshalltown | Marshalltown | Iowa | 50158 | — |
| Methodist West Hospital | West Des Moines | Iowa | 50266-7700 | — |
| Mercy Medical Center-West Lakes | West Des Moines | Iowa | 50266 | — |
| Central Care Cancer Center - Garden City | Garden City | Kansas | 67846 | — |
| Central Care Cancer Center - Great Bend | Great Bend | Kansas | 67530 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Kansas Institute of Medicine Cancer and Blood Center | Lenexa | Kansas | 66219 | — |
| Minimally Invasive Surgery Hospital | Lenexa | Kansas | 66219 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Ascension Via Christi Hospitals Wichita | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas - Wichita | Wichita | Kansas | 67214 | — |
| Wesley Medical Center | Wichita | Kansas | 67214 | — |
| Flaget Memorial Hospital | Bardstown | Kentucky | 40004 | — |
| Commonwealth Cancer Center-Corbin | Corbin | Kentucky | 40701 | — |
| Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | 40504 | — |
| Saint Joseph Hospital East | Lexington | Kentucky | 40509 | — |
| Saint Joseph London | London | Kentucky | 40741 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| Saints Mary and Elizabeth Hospital | Louisville | Kentucky | 40215 | — |
| UofL Health Medical Center Northeast | Louisville | Kentucky | 40245 | — |
| Jewish Hospital Medical Center South | Shepherdsville | Kentucky | 40165 | — |
| Ochsner Health Center-Summa | Baton Rouge | Louisiana | 70809 | — |
| Medical Center of Baton Rouge | Baton Rouge | Louisiana | 70816 | — |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Waldo County General Hospital | Belfast | Maine | 04915 | — |
| MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford | Biddeford | Maine | 04005 | — |
| Lafayette Family Cancer Center-EMMC | Brewer | Maine | 04412 | — |
| Penobscot Bay Medical Center | Rockport | Maine | 04856 | — |
| MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford | Sanford | Maine | 04073 | — |
| Mercy Medical Center | Springfield | Massachusetts | 01104 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor | Ann Arbor | Michigan | 48106 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | — |
| Trinity Health Medical Center - Brighton | Brighton | Michigan | 48114 | — |
| Henry Ford Cancer Institute-Downriver | Brownstown | Michigan | 48183 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | — |
| Trinity Health Medical Center - Canton | Canton | Michigan | 48188 | — |
| Caro Cancer Center | Caro | Michigan | 48723 | — |
| Chelsea Hospital | Chelsea | Michigan | 48118 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | 48118 | — |
| Hematology Oncology Consultants-Clarkston | Clarkston | Michigan | 48346 | — |
| Newland Medical Associates-Clarkston | Clarkston | Michigan | 48346 | — |
| Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan | 48038 | — |
| Henry Ford Medical Center-Fairlane | Dearborn | Michigan | 48126 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Henry Ford Health Saint John Hospital | Detroit | Michigan | 48236 | — |
| Henry Ford River District Hospital | East China Township | Michigan | 48054 | — |
| OSF Saint Francis Hospital and Medical Group | Escanaba | Michigan | 49829 | — |
| Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | — |
| Cancer Hematology Centers - Flint | Flint | Michigan | 48503 | — |
| Genesee Hematology Oncology PC | Flint | Michigan | 48503 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Henry Ford Saint John Hospital - Academic | Grosse Pointe Woods | Michigan | 48236 | — |
| Henry Ford Saint John Hospital - Breast | Grosse Pointe Woods | Michigan | 48236 | — |
| Henry Ford Saint John Hospital - Van Elslander | Grosse Pointe Woods | Michigan | 48236 | — |
| Allegiance Health | Jackson | Michigan | 49201 | — |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | — |
| Hope Cancer Clinic | Livonia | Michigan | 48154 | — |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | — |
| Henry Ford Saint John Hospital - Macomb Medical | Macomb | Michigan | 48044 | — |
| Henry Ford Warren Hospital - Breast Macomb | Macomb | Michigan | 48044 | — |
| Saint Mary's Oncology/Hematology Associates of Marlette | Marlette | Michigan | 48453 | — |
| MyMichigan Medical Center Midland | Midland | Michigan | 48670 | — |
| Henry Ford Medical Center-Columbus | Novi | Michigan | 48377 | — |
| Hope Cancer Center | Pontiac | Michigan | 48341 | — |
| Michigan Healthcare Professionals Pontiac | Pontiac | Michigan | 48341 | — |
| Newland Medical Associates-Pontiac | Pontiac | Michigan | 48341 | — |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | — |
| Henry Ford Rochester Hospital | Rochester Hills | Michigan | 48309 | — |
| MyMichigan Medical Center Saginaw | Saginaw | Michigan | 48601 | — |
| Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan | 48604 | — |
| Bhadresh Nayak MD PC-Sterling Heights | Sterling Heights | Michigan | 48312 | — |
| MyMichigan Medical Center Tawas | Tawas City | Michigan | 48764 | — |
| Advanced Breast Care Center PLLC | Warren | Michigan | 48088 | — |
| Henry Ford Health Warren Hospital | Warren | Michigan | 48093 | — |
| Henry Ford Madison Heights Hospital - Breast | Warren | Michigan | 48093 | — |
| Henry Ford Warren Hospital - GLCMS | Warren | Michigan | 48093 | — |
| Macomb Hematology Oncology PC | Warren | Michigan | 48093 | — |
| Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | 48322 | — |
| Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan | 48661 | — |
| Huron Gastroenterology PC | Ypsilanti | Michigan | 48106 | — |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | — |
| Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | 56601 | — |
| Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | 56401 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health - Deer River Clinic | Deer River | Minnesota | 56636 | — |
| Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota | 56501 | — |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | — |
| Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | 55805 | — |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota | 56537 | — |
| Essentia Health - Fosston | Fosston | Minnesota | 56542 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Essentia Health Hibbing Clinic | Hibbing | Minnesota | 55746 | — |
| Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | 55369 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | — |
| Monticello Cancer Center | Monticello | Minnesota | 55362 | — |
| New Ulm Medical Center | New Ulm | Minnesota | 56073 | — |
| Essentia Health - Park Rapids | Park Rapids | Minnesota | 56470 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Essentia Health Sandstone | Sandstone | Minnesota | 55072 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | — |
| Sanford Thief River Falls Medical Center | Thief River Falls | Minnesota | 56701 | — |
| Essentia Health Virginia Clinic | Virginia | Minnesota | 55792 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Sanford Cancer Center Worthington | Worthington | Minnesota | 56187 | — |
| Fairview Lakes Medical Center | Wyoming | Minnesota | 55092 | — |
| Baptist Memorial Hospital and Cancer Center-Oxford | Oxford | Mississippi | 38655 | — |
| Baptist Memorial Hospital and Cancer Center-Desoto | Southhaven | Mississippi | 38671 | — |
| Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri | 63011 | — |
| Central Care Cancer Center - Bolivar | Bolivar | Missouri | 65613 | — |
| Parkland Health Center-Bonne Terre | Bonne Terre | Missouri | 63628 | — |
| Cox Cancer Center Branson | Branson | Missouri | 65616 | — |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | — |
| Southeast Cancer Center | Cape Girardeau | Missouri | 63703 | — |
| Siteman Cancer Center at Saint Peters Hospital | City of Saint Peters | Missouri | 63376 | — |
| Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | 63141 | — |
| Centerpoint Medical Center LLC | Independence | Missouri | 64057 | — |
| MU Health Care Goldschmidt Cancer Center | Jefferson City | Missouri | 65109 | — |
| Freeman Health System | Joplin | Missouri | 64804 | — |
| Mercy Hospital Joplin | Joplin | Missouri | 64804 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | 65401 | — |
| Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | 65401 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | 63670 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| Saint Louis Cancer and Breast Institute-South City | St Louis | Missouri | 63109 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Siteman Cancer Center-South County | St Louis | Missouri | 63129 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Siteman Cancer Center at Christian Hospital | St Louis | Missouri | 63136 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Missouri Baptist Sullivan Hospital | Sullivan | Missouri | 63080 | — |
| BJC Outpatient Center at Sunset Hills | Sunset Hills | Missouri | 63127 | — |
| Mercy Hospital Washington | Washington | Missouri | 63090 | — |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | — |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | — |
| Saint Vincent Healthcare | Billings | Montana | 59101 | — |
| Saint Vincent Frontier Cancer Center | Billings | Montana | 59102 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | 59701 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Saint Peter's Community Hospital | Helena | Montana | 59601 | — |
| Logan Health Medical Center | Kalispell | Montana | 59901 | — |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | — |
| Community Medical Center | Missoula | Montana | 59804 | — |
| Nebraska Cancer Specialists/Oncology Hematology West PC | Grand Island | Nebraska | 68803 | — |
| Nebraska Medicine Heartland Hematology Oncology | Kearney | Nebraska | 68845 | — |
| CHI Health Good Samaritan | Kearney | Nebraska | 68847 | — |
| Saint Elizabeth Regional Medical Center | Lincoln | Nebraska | 68510 | — |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Hematology and Oncology Consultants PC | Omaha | Nebraska | 68122 | — |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Alegent Health Lakeside Hospital | Omaha | Nebraska | 68130 | — |
| Creighton University Medical Center | Omaha | Nebraska | 68131 | — |
| Midlands Community Hospital | Papillion | Nebraska | 68046 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| Overlook Hospital | Summit | New Jersey | 07902 | — |
| Lovelace Medical Center-Saint Joseph Square | Albuquerque | New Mexico | 87102 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| New Mexico Oncology Hematology Consultants | Albuquerque | New Mexico | 87109 | — |
| Presbyterian Kaseman Hospital | Albuquerque | New Mexico | 87110 | — |
| Presbyterian Rust Medical Center/Jorgensen Cancer Center | Rio Rancho | New Mexico | 87124 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Dickstein Cancer Treatment Center | White Plains | New York | 10601 | — |
| East Carolina University | Greenville | North Carolina | 27834 | — |
| Margaret R Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | 58103 | — |
| Sanford South University Medical Center | Fargo | North Dakota | 58103 | — |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| Essentia Health - Jamestown Clinic | Jamestown | North Dakota | 58401 | — |
| Indu and Raj Soin Medical Center | Beavercreek | Ohio | 45431 | — |
| Dayton Physicians LLC-Miami Valley South | Centerville | Ohio | 45459 | — |
| Miami Valley Hospital South | Centerville | Ohio | 45459 | — |
| Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | 45220 | — |
| Oncology Hematology Care Inc-Kenwood | Cincinnati | Ohio | 45236 | — |
| Bethesda North Hospital | Cincinnati | Ohio | 45242 | — |
| TriHealth Cancer Institute-Westside | Cincinnati | Ohio | 45247 | — |
| TriHealth Cancer Institute-Anderson | Cincinnati | Ohio | 45255 | — |
| Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Good Samaritan Hospital - Dayton | Dayton | Ohio | 45406 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Dayton Physician LLC - Englewood | Dayton | Ohio | 45415 | — |
| Miami Valley Hospital North | Dayton | Ohio | 45415 | — |
| Armes Family Cancer Center | Findlay | Ohio | 45840 | — |
| Blanchard Valley Hospital | Findlay | Ohio | 45840 | — |
| Orion Cancer Care | Findlay | Ohio | 45840 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Dayton Physicians LLC-Atrium | Franklin | Ohio | 45005 | — |
| Dayton Physicians LLC-Wayne | Greenville | Ohio | 45331 | — |
| Wayne Hospital | Greenville | Ohio | 45331 | — |
| Cleveland Clinic Cancer Center Independence | Independence | Ohio | 44131 | — |
| Greater Dayton Cancer Center | Kettering | Ohio | 45409 | — |
| First Dayton Cancer Care | Kettering | Ohio | 45420 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Cleveland Clinic Cancer Center Mansfield | Mansfield | Ohio | 44906 | — |
| Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | 44124 | — |
| North Coast Cancer Care | Sandusky | Ohio | 44870 | — |
| Springfield Regional Cancer Center | Springfield | Ohio | 45504 | — |
| Springfield Regional Medical Center | Springfield | Ohio | 45504 | — |
| Cleveland Clinic Cancer Center Strongsville | Strongsville | Ohio | 44136 | — |
| Dayton Physicians LLC - Troy | Troy | Ohio | 45373 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| South Pointe Hospital | Warrensville Heights | Ohio | 44122 | — |
| Cleveland Clinic Wooster Family Health and Surgery Center | Wooster | Ohio | 44691 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Integris Southwest Medical Center | Oklahoma City | Oklahoma | 73109 | — |
| Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | 73120 | — |
| Integris Cancer Institute of Oklahoma | Oklahoma City | Oklahoma | 73142 | — |
| Saint Alphonsus Cancer Care Center-Baker City | Baker City | Oregon | 97814 | — |
| Saint Charles Health System | Bend | Oregon | 97701 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | 97015 | — |
| Bay Area Hospital | Coos Bay | Oregon | 97420 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Saint Alphonsus Cancer Care Center-Ontario | Ontario | Oregon | 97914 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Saint Charles Health System-Redmond | Redmond | Oregon | 97756 | — |
| Jefferson Abington Hospital | Abington | Pennsylvania | 19001 | — |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | — |
| Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | 18017 | — |
| Christiana Care Health System-Concord Health Center | Chadds Ford | Pennsylvania | 19317 | — |
| Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | — |
| Ephrata Cancer Center | Ephrata | Pennsylvania | 17522 | — |
| Ephrata Community Hospital | Ephrata | Pennsylvania | 17522 | — |
| Adams Cancer Center | Gettysburg | Pennsylvania | 17325 | — |
| WellSpan Medical Oncology and Hematology | Hanover | Pennsylvania | 17331 | — |
| Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania | 18201 | — |
| Sechler Family Cancer Center | Lebanon | Pennsylvania | 17042 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania | 15232 | — |
| Penn State Health Saint Joseph Medical Center | Reading | Pennsylvania | 19605 | — |
| Asplundh Cancer Pavilion | Willow Grove | Pennsylvania | 19090 | — |
| WellSpan Health-York Cancer Center | York | Pennsylvania | 17403 | — |
| WellSpan Health-York Hospital | York | Pennsylvania | 17403 | — |
| Prisma Health Cancer Institute - Spartanburg | Boiling Springs | South Carolina | 29316 | — |
| Prisma Health Cancer Institute - Laurens | Clinton | South Carolina | 29325 | — |
| Prisma Health Cancer Institute - Easley | Easley | South Carolina | 29640 | — |
| Prisma Health Cancer Institute - Butternut | Greenville | South Carolina | 29605 | — |
| Prisma Health Cancer Institute - Faris | Greenville | South Carolina | 29605 | — |
| Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | 29605 | — |
| Prisma Health Cancer Institute - Eastside | Greenville | South Carolina | 29615 | — |
| Prisma Health Cancer Institute - Greer | Greer | South Carolina | 29650 | — |
| Prisma Health Cancer Institute - Seneca | Seneca | South Carolina | 29672 | — |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | — |
| Memorial Hospital | Chattanooga | Tennessee | 37404 | — |
| Pulmonary Medicine Center of Chattanooga-Hixson | Hixson | Tennessee | 37343 | — |
| Baptist Memorial Hospital and Cancer Center-Memphis | Memphis | Tennessee | 38120 | — |
| Memorial GYN Plus | Ooltewah | Tennessee | 37363 | — |
| Saint Joseph Regional Cancer Center | Bryan | Texas | 77802 | — |
| Covenant Medical Center-Lakeside | Lubbock | Texas | 79410 | — |
| Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | 23298 | — |
| Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | 98520 | — |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Highline Medical Center-Main Campus | Burien | Washington | 98166 | — |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | — |
| Swedish Cancer Institute-Edmonds | Edmonds | Washington | 98026 | — |
| Saint Elizabeth Hospital | Enumclaw | Washington | 98022 | — |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | — |
| Saint Francis Hospital | Federal Way | Washington | 98003 | — |
| Swedish Cancer Institute-Issaquah | Issaquah | Washington | 98029 | — |
| Kadlec Clinic Hematology and Oncology | Kennewick | Washington | 99336 | — |
| Providence Regional Cancer System-Lacey | Lacey | Washington | 98503 | — |
| Saint Clare Hospital | Lakewood | Washington | 98499 | — |
| PeaceHealth Saint John Medical Center | Longview | Washington | 98632 | — |
| Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo | Washington | 98370 | — |
| Pacific Gynecology Specialists | Seattle | Washington | 98104 | — |
| Swedish Medical Center-Ballard Campus | Seattle | Washington | 98107 | — |
| Kaiser Permanente Washington | Seattle | Washington | 98112 | — |
| Swedish Medical Center-Cherry Hill | Seattle | Washington | 98122-5711 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | — |
| PeaceHealth United General Medical Center | Sedro-Woolley | Washington | 98284 | — |
| Providence Regional Cancer System-Shelton | Shelton | Washington | 98584 | — |
| Saint Michael Cancer Center | Silverdale | Washington | 98383 | — |
| MultiCare Deaconess Cancer and Blood Specialty Center - Downtown | Spokane | Washington | 99204 | — |
| MultiCare Deaconess Cancer and Blood Specialty Center - North | Spokane | Washington | 99218 | — |
| MultiCare Deaconess Cancer and Blood Specialty Center - Valley | Spokane Valley | Washington | 99216 | — |
| Franciscan Research Center-Northwest Medical Plaza | Tacoma | Washington | 98405 | — |
| Northwest Medical Specialties PLLC | Tacoma | Washington | 98405 | — |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | — |
| Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | 99362 | — |
| Providence Regional Cancer System-Yelm | Yelm | Washington | 98597 | — |
| Edwards Comprehensive Cancer Center | Huntington | West Virginia | 25701 | — |
| Duluth Clinic Ashland | Ashland | Wisconsin | 54806 | — |
| Northwest Wisconsin Cancer Center | Ashland | Wisconsin | 54806 | — |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | — |
| Holy Family Memorial Hospital | Manitowoc | Wisconsin | 54221 | — |
| Saint Vincent Hospital Cancer Center at Marinette | Marinette | Wisconsin | 54143 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| HSHS Saint Nicholas Hospital | Sheboygan | Wisconsin | 53081 | — |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235-1495 | — |
| Cheyenne Regional Medical Center-West | Cheyenne | Wyoming | 82001 | — |
| Billings Clinic-Cody | Cody | Wyoming | 82414 | — |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03092674, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 16, 2025 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03092674 live on ClinicalTrials.gov.