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Completed Phase 2Phase 3 Interventional Results available

Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT03098030

Public ClinicalTrials.gov record NCT03098030. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 9:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Two-part, Open-label, Randomized, Phase 2/3 Study of Dinutuximab and Irinotecan Versus Irinotecan for Second Line Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer

Study identification

NCT ID
NCT03098030
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
United Therapeutics
Industry
Enrollment
483 participants

Conditions and interventions

Interventions

  • Dinutuximab Biological
  • Irinotecan Drug
  • Topotecan Drug

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2017
Primary completion
Jan 26, 2020
Completion
Mar 25, 2020
Last update posted
Dec 8, 2020

2017 – 2020

United States locations

U.S. sites
40
U.S. states
24
U.S. cities
38
Facility City State ZIP Site status
Alaska Clinical Research Center Anchorage Alaska 99503
Cancer Treatment Centers of America - Western Regional Medical Center Goodyear Arizona 85338
Innovative Clinical Research Institute Tucson Arizona 85745
Genesis Cancer Center Hot Springs Arkansas 71913
USC Norris Comprehensive Cancer Center Los Angeles California 90033
VA Palo Alto Health Care System Palo Alto California 94304
Olive View - UCLA Sylmar California 91342
Innovative Clinical Research Institute Whittier California 90603
Hartford Hospital Hartford Connecticut 06062
Eastern Connecticut Hematology and Oncology Assoc Norwich Connecticut 06360
Alpha Oncology Research LLC DeBary Florida 32713
21st Century Oncology Jacksonville Florida 32204
Comprehensive Hematology Oncology St. Petersburg Florida 33709
Winship Cancer Institute, Emory University Atlanta Georgia 30322
Northwest Georgia Oncology Centers, P.C. Marietta Georgia 30060
Baptist Health Floyd Cancer Center New Albany Indiana 47150
Physicians' Clinic of Iowa Hematology and Oncology Cedar Rapids Iowa 52403
Kentucky Cancer Clinic Hazard Kentucky 41701
University of Kentucky Lexington Kentucky 40506
21st Century Oncology Louisville Kentucky 40215
Cox Health Medical Springfield Missouri 65807
Billings Clinic Cancer Center Billings Montana 59101
St. Vincent Frontier Cancer Center Billings Montana 59102
The University of New Mexico Comprehensive Cancer Center Albuquerque New Mexico 87131
UH Cleveland Medical Center Cleveland Ohio 44106
Cancer Treatment Centers of America at Southwestern RMC Tulsa Oklahoma 74133
Kaiser Permanente Northwest Center for Health Research CRSS Portland Oregon 97227
Fox Chase Cancer Center Office of Clinical Research Philadelphia Pennsylvania 19111
Cancer Treatment Centers of America at Eastern Regional Medical Center Philadelphia Pennsylvania 19124
Charleston Oncology Charleston South Carolina 29414
Spartanburg Medical Center/Gibbs Cancer Center and Research Institute Spartanburg South Carolina 29303
Prairie Lakes Health Care Watertown South Dakota 57201
Center for Biomedical Research Knoxville Tennessee 37909
Texas Health Physicians Group Arlington Texas 76012
Plano Cancer Institute Plano Texas 75093
The University of Texas Health Science Center at Tyler, Office of Clinical Studies Tyler Texas 75701
Vista Oncology (Shelton office) Shelton Washington 98584
United Hospital Center Bridgeport West Virginia 26330
Camden Clark Medical Center / Regional Cancer Center Parkersburg West Virginia 26101
University of Wisoncsin - Carbone Cancer Ctr Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 186 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03098030, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 8, 2020 · Synced Jun 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03098030 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →