Study to Assess Safety and Efficacy of Filgotinib, Lanraplenib and Tirabrutinib in Adults With Active Sjogren's Syndrome
Public ClinicalTrials.gov record NCT03100942. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Phase 2, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of Filgotinib, GS-9876 and GS-4059 in Adult Subjects With Active Sjogren's Syndrome
Study identification
- NCT ID
- NCT03100942
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Gilead Sciences
- Industry
- Enrollment
- 152 participants
Conditions and interventions
Conditions
Interventions
- Lanraplenib Drug
- Filgotinib Drug
- Tirabrutinib Drug
- Lanraplenib placebo Drug
- Filgotinib placebo Drug
- Tirabrutinib placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2017
- Primary completion
- Jan 9, 2019
- Completion
- Oct 1, 2019
- Last update posted
- Oct 22, 2020
2017 – 2019
United States locations
- U.S. sites
- 34
- U.S. states
- 19
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AARR Arizona Arthritis & Rheumatology Research | Mesa | Arizona | 85202 | — |
| AARR Arizona Arthritis & Rheumatology Research | Phoenix | Arizona | 85032 | — |
| Medvin Clinical Research | Covina | California | 91723 | — |
| Inland Rheumatology Clinical Trials, Inc. | Upland | California | 91786 | — |
| Denver Arthritis Clinic | Denver | Colorado | 80230 | — |
| Clinical Research of West Florida, Inc. | Clearwater | Florida | 33765 | — |
| Omega Research Consultants LLC | DeBary | Florida | 32713 | — |
| Center for Rheumatology Immunology and Arthritis | Fort Lauderdale | Florida | 33309 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34668 | — |
| IRIS Research and Development, LLC | Plantation | Florida | 33324 | — |
| North Georgia Rheumatology Group, PC | Lawrenceville | Georgia | 30046 | — |
| Springfield Clinic | Springfield | Illinois | 62703 | — |
| Center for Arthritis & Osteoporosis | Elizabethtown | Kentucky | 42701 | — |
| June DO, PC | Lansing | Michigan | 48910 | — |
| North Mississippi Medical Clinics, Inc. - Clinical Research | Tupelo | Mississippi | 38801 | — |
| Clayton Medical Associates | St Louis | Missouri | 63117 | — |
| Physician Research Collaboration, LLC | Lincoln | Nebraska | 68516 | — |
| Albuquerque Clinical Trials | Albuquerque | New Mexico | 87102 | — |
| Joint and Muscle Research Institute | Charlotte | North Carolina | 28204 | — |
| Cape Fear Arthritis Care, PLLC | Leland | North Carolina | 28451 | — |
| PMG Research of Salisbury | Salisbury | North Carolina | 28144 | — |
| East Penn Rheumatology Associates, P.C. | Bethlehem | Pennsylvania | 18015 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Clinical Research Center of Reading, LLC | Wyomissing | Pennsylvania | 19610 | — |
| ClinSearch | Chattanooga | Tennessee | 37421 | — |
| Ramesh C. Gupta, MD | Memphis | Tennessee | 38119 | — |
| Diagnostic Group Integrated Healthcare System, Pllc | Beaumont | Texas | 77701 | — |
| Accurate Clinical Research Inc. | Houston | Texas | 77034 | — |
| Southwest Rheumatology Research | Mesquite | Texas | 75150 | — |
| Trinity Universal Research Associates | Plano | Texas | 75024 | — |
| Arthritis & Osteoporosis Clinic | Waco | Texas | 76710 | — |
| Wasatch Peak Family Practice | Layton | Utah | 84041 | — |
| The Center for Arthritis and Rheumatic Diseases, PC | Chesapeake | Virginia | 23320 | — |
| Arthritis Northwest | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03100942, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 22, 2020 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03100942 live on ClinicalTrials.gov.