LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
Public ClinicalTrials.gov record NCT03103087. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
LIBERTY 2: An International Phase 3 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study to Evaluate Relugolix Co-Administered With and Without Low-Dose Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the benefit of relugolix 40 milligrams (mg) once a day co-administered with estradiol (E2) 1 mg and norethindrone acetate (NETA) 0.5 mg compared with placebo for 24 weeks on heavy menstrual bleeding associated with uterine fibroids.
Study identification
- NCT ID
- NCT03103087
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 382 participants
Conditions and interventions
Conditions
Interventions
- Relugolix Drug
- Estradiol/norethindrone acetate Drug
- Relugolix placebo Drug
- Estradiol/norethindrone acetate placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 14, 2017 (Actual)
- Primary completion
- Jul 10, 2019 (Actual)
- Completion
- Sep 16, 2020 (Actual)
- Last update posted
- Apr 20, 2022
2017 – 2020
United States locations
- U.S. sites
- 89
- U.S. states
- 26
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham | Birmingham | Alabama | 35205 | — |
| Mesa | Mesa | Arizona | 85209 | — |
| Tucson | Tucson | Arizona | 85704 | — |
| Tuscon | Tucson | Arizona | 85712 | — |
| Canoga Park | Canoga Park | California | 91303 | — |
| Huntington Beach | Huntington Beach | California | 92647 | — |
| Long Beach | Long Beach | California | 90806 | — |
| Los Angeles | Los Angeles | California | 90036 | — |
| Los Angeles | Los Angeles | California | 90057 | — |
| Panorama | Panorama City | California | 91402 | — |
| San Diego | San Diego | California | 92114 | — |
| Upland | Upland | California | 91786 | — |
| Denver | Denver | Colorado | 80209 | — |
| Lakewood | Lakewood | Colorado | 80228 | — |
| Washington | Washington D.C. | District of Columbia | 20036 | — |
| Aventura | Aventura | Florida | 33180 | — |
| DeLand | DeLand | Florida | 32720 | — |
| Ft. Lauderdale | Fort Lauderdale | Florida | 33316 | — |
| Jupiter | Jupiter | Florida | 33458 | — |
| Lake City | Lake City | Florida | 32055 | — |
| Loxahachee | Loxahatchee Groves | Florida | 33470 | — |
| Miami | Miami | Florida | 33126 | — |
| Miami | Miami | Florida | 33155 | — |
| Miami Springs | Miami Springs | Florida | 33166 | — |
| New Port Richey | New Port Richey | Florida | 34652 | — |
| North Miami | North Miami | Florida | 33161 | — |
| Oviedo | Oviedo | Florida | 32765 | — |
| Plantation | Plantation | Florida | 33324 | — |
| Port St. Lucie | Port Saint Lucie | Florida | 34952 | — |
| Saint Cloud | Saint Cloud | Florida | 34769 | — |
| Sarasota | Sarasota | Florida | 34239 | — |
| Stuart | Stuart | Florida | 34996 | — |
| Tampa | Tampa | Florida | 33606 | — |
| Wellington | Wellington | Florida | 33414 | — |
| West Palm Beach | West Palm Beach | Florida | 33409 | — |
| Atlanta | Atlanta | Georgia | 30312 | — |
| Decatur | Decatur | Georgia | 30034 | — |
| Duluth | Duluth | Georgia | 30097 | — |
| Norcross | Norcross | Georgia | 30093 | — |
| Sandy Springs | Sandy Springs | Georgia | 30328 | — |
| Savannah | Savannah | Georgia | 31406 | — |
| Idaho Falls | Idaho Falls | Idaho | 83404 | — |
| Nampa | Nampa | Idaho | 83686 | — |
| Champaign | Champaign | Illinois | 61820 | — |
| Chicago | Chicago | Illinois | 60611 | — |
| Naperville | Naperville | Illinois | 60540 | — |
| Oakbrook | Oak Brook | Illinois | 60523 | — |
| Avon | Avon | Indiana | 46123 | — |
| Shawnee | Shawnee Mission | Kansas | 66128 | — |
| Marrero | Marrero | Louisiana | 70072 | — |
| Metairie | Metairie | Louisiana | 70006 | — |
| New Orleans | New Orleans | Louisiana | 70115 | — |
| Baltimore | Baltimore | Maryland | 21208 | — |
| Towson | Towson | Maryland | 21204 | — |
| Bay City | Bay City | Michigan | 48706 | — |
| Canton | Canton | Michigan | 48187 | — |
| Detroit | Detroit | Michigan | 48201 | — |
| Saginaw | Saginaw | Michigan | 48604 | — |
| Norfolk | Norfolk | Nebraska | 68701 | — |
| Las Vegas | Las Vegas | Nevada | 89106 | — |
| Las Vegas | Las Vegas | Nevada | 89109 | — |
| Las Vegas | Las Vegas | Nevada | 89113 | — |
| New Brunswick | New Brunswick | New Jersey | 08901 | — |
| Albuquerque | Albuquerque | New Mexico | 87102 | — |
| Brooklyn | Brooklyn | New York | 11201 | — |
| New York | New York | New York | 10022 | — |
| New York | New York | New York | 10038 | — |
| Rochester | Rochester | New York | 14642 | — |
| Durham | Durham | North Carolina | 27713 | — |
| Raleigh | Raleigh | North Carolina | 27607 | — |
| Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| Cincinnati | Cincinnati | Ohio | 45212 | — |
| Columbus | Columbus | Ohio | 43231 | — |
| West Reading | West Reading | Pennsylvania | 19611 | — |
| Charleston | Charleston | South Carolina | 29406 | — |
| Beaumont | Beaumont | Texas | 77702 | — |
| Dallas | Dallas | Texas | 75231 | — |
| Dallas | Dallas | Texas | 75234 | — |
| Fort Worth | Fort Worth | Texas | 76104 | — |
| Frisco | Frisco | Texas | 75035 | — |
| Houston | Houston | Texas | 77030 | — |
| Houston | Houston | Texas | 77054 | — |
| Longview | Longview | Texas | 75605 | — |
| San Antonio | San Antonio | Texas | 78258 | — |
| Virginia Beach | Norfolk | Virginia | 23502 | — |
| Richmond | Richmond | Virginia | 23225 | — |
| Covington | Covington | Washington | 98042 | — |
| Puyallup | Puyallup | Washington | 98372 | — |
| Spokane | Spokane | Washington | 99207 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03103087, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2022 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03103087 live on ClinicalTrials.gov.