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Completed Phase 1Phase 2 Interventional Results available

A Study of AGEN2034 in Advanced Tumors and Cervical Cancer

ClinicalTrials.gov ID: NCT03104699

Public ClinicalTrials.gov record NCT03104699. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 31, 2026, 9:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2, Open-Label, Multiple Ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological, and Clinical Activity of AGEN2034 in Subjects With Metastatic or Locally Advanced Solid Tumors, With Expansion to Second Line Cervical Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a 2-part trial: a Phase 1, open-label, dose-escalation study in participants with metastatic or locally advanced solid tumors, with a consecutive Phase 2 expansion to evaluate efficacy in participants with recurrent, unresectable, or metastatic (advanced) cervical cancer that has progressed after a platinum-based treatment regimen.

Study identification

NCT ID
NCT03104699
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Agenus Inc.
Industry
Enrollment
211 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 11, 2017 (Actual)
Primary completion
Jun 15, 2022 (Actual)
Completion
Jun 15, 2022 (Actual)
Last update posted
Jul 30, 2025

2017 – 2022

United States locations

U.S. sites
12
U.S. states
10
U.S. cities
12
Facility City State ZIP Site status
HonorHealth Research Institute Scottsdale Arizona 85258 —
City of Hope Duarte California 91010 —
University of Southern California - Keck School of Medicine Los Angeles California 90033 —
Sylvester Comprehensive Cancer Center Miami Florida 33136 —
Florida Cancer Specialists & Research Institute Sarasota Florida 34232 —
Augusta Oncology Augusta Georgia 30912 —
Robert H. Lurie Comprehensive Cancer Center of Northwestern University Chicago Illinois 60611 —
Dana Farber Cancer Institute Boston Massachusetts 02215 —
The Ohio State University Comprehensive Cancer Center Columbus Ohio 43210 —
The University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 —
The University of Texas MD Anderson Cancer Center Houston Texas 77030 —
Swedish Medical Center-Cherry Hill Campus Seattle Washington 98104 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03104699, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 30, 2025 · Synced Oct 31, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03104699 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →