Induction Chemotherapy for Locally Advanced Esophageal Cancer

ClinicalTrials.gov ID: NCT03110926

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Official title

Induction Chemotherapy for Locally Advanced Esophageal Cancer: A Phase II Study

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Evaluate mFOLFOX6 (5-Fluorouracil, Leucovorin and Oxaliplatin) chemotherapy as induction treatment prior to standard neoadjuvant chemoradiation to decrease the rate of distant recurrence among patients with locally advanced esophageal cancer.

Study identification

NCT ID: NCT03110926
Recruitment status: Active, not recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: University of Rochester; Other
Enrollment: 40 participants

Conditions and interventions

Conditions

Esophageal Carcinoma

Interventions

mFOLFOX6 Drug
Chemoradiation Combination Product

Drug · Combination Product

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 19, 2017 (Actual)
Primary completion: May 31, 2027 (Estimated)
Completion: May 31, 2027 (Estimated)
Last update posted: Sep 12, 2025

2017 – 2027

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Rochester	Rochester	New York	14642	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT03110926, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 12, 2025 · Synced Nov 12, 2026