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Completed Phase 3 Interventional Results available

Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (MCL)

ClinicalTrials.gov ID: NCT03112174

Public ClinicalTrials.gov record NCT03112174. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 12, 2026, 2:20 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 3 Study of Ibrutinib in Combination With Venetoclax in Subjects With Mantle Cell Lymphoma

Study identification

NCT ID
NCT03112174
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pharmacyclics LLC.
Industry
Enrollment
366 participants

Conditions and interventions

Interventions

  • Ibrutinib Drug
  • Placebo Oral tablet to match Venetoclax Drug
  • Venetoclax Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 18, 2017
Primary completion
Jun 25, 2024
Completion
Jun 26, 2024
Last update posted
Jul 21, 2025

2017 – 2024

United States locations

U.S. sites
14
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
The University of Arizona Cancer Centre-North Campus Tucson Arizona 85719
City of Hope Duarte California 91010
UCLA Department of Medicine-Hematology/Oncology Los Angeles California 90095
Orlando Health Inc. Orlando Florida 32806
The University of Kansas Cancer Center and Medical Pavilion Westwood Kansas 66205
Norton Cancer Institute Louisville Kentucky 40207
Barbara Ann Karmanos Cancer institute Detroit Michigan 48201
Memorial Sloan Kettering Cancer Center New York New York 10065
Stony Brook University New York New York 11794
Levine Cancer Institute Charlotte North Carolina 28204
Tennessee Oncology Chattanooga Tennessee 37404
University of Tennessee medical Center Knoxville Tennessee 37920
University of Texas MD Anderson Cancer Center Houston Texas 77030
Swedish Cancer Institute Seattle Washington 98194

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 106 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03112174, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 21, 2025 · Synced May 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03112174 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →