Efficacy and Safety of Olokizumab in Subjects With Moderately to Severely Active Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT03120949. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumab in Subjects With Moderately to Severely Active Rheumatoid Arthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study was to evaluate the long-term safety and tolerability of olokizumab (OKZ) 64 mg administered subcutaneously (SC) once every 2 weeks (q2w) or once every 4 weeks (q4w) in subjects with moderately to severely active rheumatoid arthritis (RA) who previously had completed 24 weeks of double-blind treatment in Study CREDO 1, 2 or 3 (core studies). The long-term efficacy, immunogenicity, the physical function and quality of life of subjects received long-term treatment with OKZ were assessed as well.
Study identification
- NCT ID
- NCT03120949
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,106 participants
Conditions and interventions
Conditions
Interventions
- Olokizumab 64 mg SC q4w Drug
- Olokizumab 64 mg SC q2w Drug
- Concomitant treatment Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 4, 2017 (Actual)
- Primary completion
- Sep 1, 2021 (Actual)
- Completion
- Sep 1, 2021 (Actual)
- Last update posted
- Oct 12, 2023
2017 – 2021
United States locations
- U.S. sites
- 71
- U.S. states
- 29
- U.S. cities
- 64
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AZ Arthritis & Rheum' Research | Mesa | Arizona | 85210 | — |
| Arizona Arthritis & Rheumatology Associates, P.C. | Phoenix | Arizona | 85032 | — |
| Arizona Arthritis & Rheumatology Research, PLLC | Sun City | Arizona | 85351 | — |
| CHI St. Vincent Hot Springs | Hot Springs | Arkansas | 71913 | — |
| Medvin Clinical Research | Covina | California | 91722 | — |
| C.V Mehta MD Med Corp.. | Hemet | California | 92543 | — |
| Advanced Medical Research, LLC | La Palma | California | 90623 | — |
| Valerius Medical Group | Los Alamitos | California | 90720-5403 | — |
| Stanford University School of Medicine | Palo Alto | California | 94304 | — |
| Rheumatology Center of San Diego | San Diego | California | 92128 | — |
| East Bay Rheumatology Medical Group, Inc. | San Leandro | California | 94578 | — |
| Inland Rheumatology Clinical Trials, Inc. | Upland | California | 91786 | — |
| Center for Rheumatology Research, Comprehensive Rheumatology Center | West Hills | California | 91307 | — |
| Medvin Clinical Research | Whittier | California | 90602 | — |
| Denver Arthritis Clinic | Denver | Colorado | 80230 | — |
| New England Research Associates LLC | Bridgeport | Connecticut | 06606 | — |
| Javed Rheumatology Associates | Newark | Delaware | 19713 | — |
| RASF - Clinical Research Center | Boca Raton | Florida | 33486 | — |
| Reliable Clinical Research, LLC | Hialeah | Florida | 33012 | — |
| Pharmax Research Clinic | Miami | Florida | 33126 | — |
| Medical Research Center of Miami | Miami | Florida | 33134 | — |
| Suncoast Research Group, LLC | Miami | Florida | 33135 | — |
| Omega Research Consultants | Orlando | Florida | 32810 | — |
| Arthritis Research of Florida, INC | Palm Harbor | Florida | 34684 | — |
| Family Clinical Trials, LLC. | Pembroke Pines | Florida | 33026 | — |
| AdventHealth Medical Group, PA | Tampa | Florida | 33614 | — |
| Lovelace Scientific Resources, Inc. | Venice | Florida | 34292 | — |
| Arthritis Center of North Georgia | Gainesville | Georgia | 30501 | — |
| Marietta Rheumatology Associates, PC | Marietta | Georgia | 30060 | — |
| Institute of Arthritis Research | Idaho Falls | Idaho | 83404 | — |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Graves Gilbert Clinic | Bowling Green | Kentucky | 42101 | — |
| The Arthritis & Diabetes Clinic, Inc. | Monroe | Louisiana | 71203 | — |
| Klein and Associates, M.D., P.A. | Hagerstown | Maryland | 21740 | — |
| The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| Clinical Pharmacology Study Group | Worcester | Massachusetts | 01605 | — |
| AA MRC LLC Ahmed Arif Medical Research Center | Grand Blanc | Michigan | 48439 | — |
| North MS Medical Clinics, Inc. | Tupelo | Mississippi | 38801 | — |
| Glacier View Research Institute-Rheumatology | Kalispell | Montana | 59901 | — |
| Physician Research Collaboration | Lincoln | Nebraska | 68516 | — |
| Arthritis & Osteoporosis Associates, PA | Freehold | New Jersey | 07728 | — |
| Lovelace Scientific Resources, Inc. | Albuquerque | New Mexico | 87114 | — |
| NYU Langone ambulatory care | Brooklyn | New York | 11201 | — |
| Medication Management, LLC | Greensboro | North Carolina | 27408 | — |
| Cape Fear Arthritis Care | Leland | North Carolina | 28451 | — |
| Carolina Arthritis Associates | Wilmington | North Carolina | 28401 | — |
| Trinity Medical Group | Minot | North Dakota | 58701 | — |
| Cincinnati Rheumatic Disease Study Group | Cincinnati | Ohio | 45242 | — |
| STAT Research, Inc. | Dayton | Ohio | 45417 | — |
| Clinical Research Source, Inc. | Toledo | Ohio | 43606 | — |
| Health Research of Oklahoma, PLLC | Oklahoma City | Oklahoma | 73103 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Altoona Center for Clinical Research, P.C. | Duncansville | Pennsylvania | 16635 | — |
| Arthritis Group | Philadelphia | Pennsylvania | 19152 | — |
| Low Country Rheumatology, PA | Summerville | South Carolina | 29486 | — |
| Amarillo Center for Clinical Research | Amarillo | Texas | 79124 | — |
| Austin Regional Clinic, P.A. | Austin | Texas | 78731 | — |
| Accurate Clinical Management., LLC | Baytown | Texas | 77521 | — |
| Precision Comprehensive Clinical Research Solutions | Colleyville | Texas | 76034 | — |
| Pioneer Research Solutions, Inc. | Cypress | Texas | 77429 | — |
| Therapeutic Concepts Rheumatology,LLC | Houston | Texas | 77004 | — |
| Rheumatology Clinic of Houston, P.A. | Houston | Texas | 77065 | — |
| Houston Institute For Clinical Research | Houston | Texas | 77074 | — |
| Accurate Clinical Mangemnt - Partner | Houston | Texas | 77089 | — |
| Accurate Clinical Research, Inc. | Houston | Texas | 77089 | — |
| Accurate Clinical Research, Inc. | League City | Texas | 77573 | — |
| West Texas Clinical Research | Lubbock | Texas | 79410 | — |
| Dr Alex De Jesus Rheumatology, P.A. | San Antonio | Texas | 78229 | — |
| Advanced Rheumatology of Houston | The Woodlands | Texas | 77382 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
| Arthritis Northwest, PLLC | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 168 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03120949, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 12, 2023 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03120949 live on ClinicalTrials.gov.