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Completed Phase 2 Interventional Results available

A Study to Evaluate the Safety and Efficacy of Nivolumab Monotherapy and Nivolumab in Combination With Ipilimumab in Pediatric Participants With High Grade Primary Central Nervous System (CNS) Malignancies

ClinicalTrials.gov ID: NCT03130959

Public ClinicalTrials.gov record NCT03130959. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 12:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase Ib /II Clinical Trial of Nivolumab Monotherapy and Nivolumab in Combination With Ipilimumab in Pediatric Subjects With High Grade Primary CNS Malignancies

Study identification

NCT ID
NCT03130959
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
166 participants

Conditions and interventions

Interventions

  • Nivolumab Biological
  • Ipilimumab Biological

Biological

Eligibility (public fields only)

Age range
6 Months to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 11, 2017
Primary completion
Mar 9, 2020
Completion
Jan 16, 2022
Last update posted
Aug 8, 2022

2017 – 2022

United States locations

U.S. sites
14
U.S. states
13
U.S. cities
13
Facility City State ZIP Site status
Local Institution - 0057 Los Angeles California 90027
Local Institution - 0016 Aurora Colorado 80045
Local Institution - 0046 Gainesville Florida 32611
Local Institution - 0011 Chicago Illinois 60611-2605
Local Institution - 0005 Baltimore Maryland 21287
Local Institution - 0043 Boston Massachusetts 02215
Local Institution - 0044 St Louis Missouri 63110
Local Institution - 0004 New York New York 10021
Local Institution - 0017 New York New York 10032
Cincinnati Children'S Hospital Medical Center Cincinnati Ohio 45229
Local Institution - 0066 Philadelphia Pennsylvania 19104
Local Institution Charleston South Carolina 29425
Local Institution - 0012 Memphis Tennessee 38105
Local Institution - 0042 Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03130959, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 8, 2022 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03130959 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →