ClinicalTrials.gov record
A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease
ClinicalTrials.gov ID: NCT03131453
Public ClinicalTrials.gov record NCT03131453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy and Safety of CNP520 in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (AD).
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the effects of CNP520 on cognition, global clinical status, and underlying AD pathology, as well as the safety of CNP520, in people at risk for the onset of clinical symptoms of AD based on their age, APOE genotype and elevated amyloid.
Study identification
- NCT ID
- NCT03131453
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 1,145 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 3, 2017 (Actual)
- Primary completion
- Mar 26, 2020 (Actual)
- Completion
- Mar 26, 2020 (Actual)
- Last update posted
- Aug 5, 2021
2017 – 2020
United States locations
- U.S. sites
- 95
- U.S. states
- 35
- U.S. cities
- 86
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute, 901 East Willetta Street | Phoenix | Arizona | 85006 | — |
| Banner Sun Health Research Institute, 10515 West Santa Fe Drive, Building B | Sun City | Arizona | 85351 | — |
| Novartis Investigative Site | Tucson | Arizona | 85724 | — |
| ATP Clinical Research Inc, 3151 Airway Avenue T 3 | Costa Mesa | California | 92626 | — |
| Irvine Center for Clinical Res, 2515 McCabe Way | Irvine | California | 92618 | — |
| Torrance Clinical Research Institute, 25043 Narbonne Avenue | Lomita | California | 90717 | — |
| Novartis Investigative Site | Oxnard | California | 93030 | — |
| Novartis Investigative Site | Palo Alto | California | 94304 | — |
| Novartis Investigative Site | San Diego | California | 92103 | — |
| Syrentis Clinical Research, 1401 N Tustin Ave, Suite 130 | Santa Ana | California | 92705 | — |
| Novartis Investigative Site | Sebastopol | California | 95472 | — |
| Novartis Investigative Site | Sherman Oaks | California | 91403 | — |
| Mountain Neurological Research, 350 Market Street, Suite 316 | Basalt | Colorado | 81621 | — |
| Colorado Springs Neurological, 2312 North Nevada Avenue, Suite 100 | Colorado Springs | Colorado | 80907 | — |
| Denver Neurological Clinic, 950 E Harvard Ave | Denver | Colorado | 80210 | — |
| Yale University, One Church Street, Suite 600 | New Haven | Connecticut | 06519 | — |
| Novartis Investigative Site | Stamford | Connecticut | 06905 | — |
| Novartis Investigative Site | Washington D.C. | District of Columbia | 20057 | — |
| Novartis Investigative Site | Atlantis | Florida | 33462-6608 | — |
| Quantum Laboratories | Deerfield Beach | Florida | 33064 | — |
| Brain Matters Research, Inc., 800 NW 17th Avenue | Delray Beach | Florida | 33445 | — |
| Infinity Clinical Research LLC, 4925 Sheridan Street, Suite 200 | Hollywood | Florida | 33021 | — |
| Alzheimer's Research and Treatment Center, 5065 State Road 7, Suite 102 | Lake Worth | Florida | 33449 | — |
| Meridien Research, 2300 Maitland center, Pkwy Ste 230 | Maitland | Florida | 32751 | — |
| Novartis Investigative Site | Melbourne | Florida | 32940 | — |
| Novartis Investigative Site | Merritt Island | Florida | 32952 | — |
| Novartis Investigative Site | Miami | Florida | 33032 | — |
| Novartis Investigative Site | Miami | Florida | 33136 | — |
| New Horizon Research Center, 11880 SW 40 St., Suite 405 | Miami | Florida | 33175 | — |
| Miami-Dade Medical Research, 8955 SW 87 CT, Suite 112 | Miami | Florida | 33176 | — |
| Novartis Investigative Site | Miami Beach | Florida | 33140 | — |
| Compass Research, LLC,100 West Gore Street, Suite 202 | Orlando | Florida | 32806 | — |
| Novartis Investigative Site | Orlando | Florida | 32806 | — |
| Novartis Investigative Site | Ormond Beach | Florida | 32174 | — |
| Novartis Investigative Site | Palm Beach Gardens | Florida | 33410 | — |
| Novartis Investigative Site | Port Orange | Florida | 32127 | — |
| Roskamp Institute, Inc., 2040 Whitfield Avenue | Sarasota | Florida | 34243 | — |
| Novartis Investigative Site | Tallahassee | Florida | 32308 | — |
| Novartis Investigative Site | Tampa | Florida | 33613 | — |
| Novartis Investigative Site | West Palm Beach | Florida | 33407 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30322 | — |
| Novartis Investigative Site | Columbus | Georgia | 31909 | — |
| Novartis Investigative Site | Decatur | Georgia | 30033 | — |
| Hawaii Pacific Neuroscience, 2230 Liliha st 104 | Honolulu | Hawaii | 96817 | — |
| Advanced Clinical Research, 2950 E Magic View Dr, Suite 182 | Meridian | Idaho | 83642 | — |
| Novartis Investigative Site | Chicago | Illinois | 60612 | — |
| Novartis Investigative Site | Chicago | Illinois | 60640 | — |
| Alexian Brothers Neuroscience, 800 Biesterfield Rd, Neuroscience Institute Brock | Elk Grove Village | Illinois | 60007 | — |
| Novartis Investigative Site | Indianapolis | Indiana | 46202 | — |
| Novartis Investigative Site | Fairway | Kansas | 66205 | — |
| Novartis Investigative Site | Wichita | Kansas | 67206 | — |
| Novartis Investigative Site | Wichita | Kansas | 67214 | — |
| Novartis Investigative Site | Lexington | Kentucky | 40536-0284 | — |
| Novartis Investigative Site | Bangor | Maine | 04401 | — |
| Novartis Investigative Site | Boston | Massachusetts | 02118 | — |
| Novartis Investigative Site | Boston | Massachusetts | 02215 | — |
| QUEST Research Institute, 28595 Orchard Lake Road, Suite 301 | Farmington Hills | Michigan | 48334 | — |
| Novartis Investigative Site | Kalamazoo | Michigan | 49008 | — |
| Novartis Investigative Site | Rochester | Minnesota | 55905 | — |
| Hattiesburg Clinic, 415 South 28th Avenue | Hattiesburg | Mississippi | 39401 | — |
| Novartis Investigative Site | St Louis | Missouri | 63104 | — |
| Novartis Investigative Site | Omaha | Nebraska | 68198 7680 | — |
| Novartis Investigative Site | West Long Branch | New Jersey | 07764 | — |
| Albuquerque Neuroscience, 101 Hospital Loop ne, 209 209 | Albuquerque | New Mexico | 87109 | — |
| Novartis Investigative Site | Brooklyn | New York | 11235 | — |
| Novartis Investigative Site | East Syracuse | New York | 13057 | — |
| Novartis Investigative Site | Latham | New York | 12110 | — |
| NYU Langone Medical Center, 145 East 32nd Street, 2nd Floor, Room 226 | New York | New York | 10016 | — |
| Novartis Investigative Site | Orangeburg | New York | 10962 | — |
| Novartis Investigative Site | Rochester | New York | 14642 | — |
| ANI Neurology, PLLC dba Alzhe, 7809 Sardis Road | Charlotte | North Carolina | 28270 | — |
| Novartis Investigative Site | Durham | North Carolina | 27710 | — |
| Novartis Investigative Site | Greensboro | North Carolina | 27410 | — |
| Novartis Investigative Site | Cincinnati | Ohio | 45242 | — |
| Novartis Investigative Site | Oklahoma City | Oklahoma | 73112 | — |
| Tulsa Clinical Research LLC, 1705 E 19th ST., STE 406/408 | Tulsa | Oklahoma | 74104 | — |
| Summit Research Network, 2701 NW Vaughn St, Suite 350 | Portland | Oregon | 97210 | — |
| Novartis Investigative Site | Portland | Oregon | 97239 | — |
| Novartis Investigative Site | Jenkintown | Pennsylvania | 19046 | — |
| Novartis Investigative Site | Philadelphia | Pennsylvania | 19104 | — |
| Abington Neurological Associate Ltd., 2325 Maryland Road, Suite 100 | Willow Grove | Pennsylvania | 19090 | — |
| Rhode Island Hospital and Memory Research Institute, 1018 Waterman Ave | East Providence | Rhode Island | 02914 | — |
| Butler Hospital, 345 Blackstone Blvd. | Providence | Rhode Island | 02906 | — |
| Roper Hospital, 316 Calhoun Street 5th Floor | Charleston | South Carolina | 29401 | — |
| Novartis Investigative Site | Knoxville | Tennessee | 37920 | — |
| Novartis Investigative Site | Memphis | Tennessee | 38119 | — |
| Novartis Investigative Site | Nashville | Tennessee | 37212 | — |
| Novartis Investigative Site | Austin | Texas | 78757 | — |
| Novartis Investigative Site | Dallas | Texas | 75231 | — |
| Novartis Investigative Site | Houston | Texas | 77030 | — |
| Novartis Investigative Site | Houston | Texas | 77054 | — |
| Novartis Investigative Site | San Antonio | Texas | 78229 | — |
| Novartis Investigative Site | Bennington | Vermont | 05201 | — |
| Novartis Investigative Site | Tacoma | Washington | 98405 | — |
| Novartis Investigative Site | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 99 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03131453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2021 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03131453 live on ClinicalTrials.gov.