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Completed Phase 4 Interventional Results available

Zoster Eye Disease Study

ClinicalTrials.gov ID: NCT03134196

Public ClinicalTrials.gov record NCT03134196. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 18, 2026, 9:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Long-term Suppressive Valacyclovir Treatment for Herpes Zoster Ophthalmicus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multi-center, randomized, double-masked, placebo-controlled clinical trial of suppressive valacyclovir for one year in immunocompetent study participants with an episode of dendriform epithelial keratitis, stromal keratitis, endothelial keratitis, and/or iritis due to Herpes Zoster Ophthalmicus (HZO) in the year prior to enrollment.

Study identification

NCT ID
NCT03134196
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
NYU Langone Health
Other
Enrollment
527 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 23, 2017 (Actual)
Primary completion
Dec 31, 2023 (Actual)
Completion
Jul 22, 2024 (Actual)
Last update posted
Mar 7, 2025

2017 – 2024

United States locations

U.S. sites
71
U.S. states
31
U.S. cities
61
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233 —
Mayo Clinic - Arizona Scottsdale Arizona 85259 —
University of Arkansas for Medical Sciences Little Rock Arkansas 72205 —
Scripps Clinic La Jolla California 92037 —
Loma Linda University Eye Institute Loma Linda California 92354 —
Jules Stein Eye Clinic - UCLA Los Angeles California 90095 —
Byers Eye Institute at Stanford University Palo Alto California 94303 —
UCSF- Francis I. Proctor Foundation San Francisco California 94131 —
Pacific Eye Surgeons, Inc. San Luis Obispo California 93401 —
University of Colorado Aurora Colorado 80045 —
Colorado Cornea Consultants P.C. Littleton Colorado 80120 —
Medstar Georgetown University Hospital Washington D.C. District of Columbia 20007 —
Delray Eye Associates, PA Delray Beach Florida 33484 —
University of Florida Gainesville Florida 32610 —
Florida Eye Specialists Jacksonville Florida 33204 —
University of Miami - Bascom Palmer Eye Institute Miami Florida 33136 —
Eye Consultants of Atlanta, PC Atlanta Georgia 30339 —
University of Illinois Chicago Illinois 60612 —
NorthShore University Health System Glenview Illinois 60026 —
Case Western Reserve University Cleveland Indiana 44106 —
Indiana University - Glick Eye Institute Indianapolis Indiana 46202 —
University of Kansas Medical Center Prairie Village Kansas 66208 —
University of Kentucky Lexington Kentucky 40509 —
LSU Health Science Center New Orleans Louisiana 70112 —
Shreveport Eye Clinic Shreveport Louisiana 71106 —
University of Maryland Baltimore Maryland 21201 —
The Krieger Eye Institute Baltimore Maryland 21215 —
Wilmer Eye Institute John Hopkins Bethesda Maryland 20817 —
Crossroads Eye Physician Owings Mills Maryland 21117 —
Tufts Medical Center Boston Massachusetts 02111 —
Massachusetts Eye and Ear Infirmary Boston Massachusetts 02114 —
Boston Medical Center Boston Massachusetts 02118 —
Lahey Medical Center Peabody Massachusetts 01960 —
Eye Health Services Weymouth Massachusetts 02189 —
University of Michigan Ann Arbor Michigan 48105 —
Verdier Eye Center Grand Rapids Michigan 49546 —
Northwest Eye Clinic Golden Valley Minnesota 55427 —
Jennifer Burdick Minnetonka Minnesota 55305 —
Mayo Clinic Rochester Minnesota 55905 —
Washington University Opthalmology St Louis Missouri 63110 —
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756 —
EyeCare MD of NJ Morristown New Jersey 07960 —
Albany Stratton VA Medical Center Albany New York 12208 —
Finger Lakes Ophthalmology /The Eye Care Center Canandaigua New York 14424 —
Stony Brook Ophthalmology East Setauket New York 11733 —
Northwell Health Great Neck New York 11021 —
New York Eye and Ear Infirmary New York New York 10003 —
NYU Langone Health New York New York 10016 —
Weill Cornell Ophthalmology New York New York 10021 —
Duke University Durham North Carolina 27710 —
Cincinnati Eye Institute Cincinnati Ohio 45242 —
Case Western Reserve University Cleveland Ohio 44106 —
Devers Eye Institute Portland Oregon 97210 —
Casey Eye Institute - Oregon Health and Science University Portland Oregon 97239 —
Vantage Eye Care Center, LLC Bala-Cynwyd Pennsylvania 19004 —
Geisinger Eye Clinic Danville Pennsylvania 17822 —
University of Pennsylvania Philadelphia Pennsylvania 19104 —
Corneal Associates at Wills Eye Hospital Philadelphia Pennsylvania 19107 —
University of Tennessee - Hamilton Eye Institute Memphis Tennessee 38163 —
Cornea and Cataract Consultants of Nashville Nashville Tennessee 37203 —
Vanderbilt Eye Institute Nashville Tennessee 37232 —
Cornea Associates of Texas Dallas Texas 75231 —
University of Texas Southwestern Dallas Texas 75390 —
Cornea Consultants of Texas Fort Worth Texas 76107 —
Alkek Eye Center - Baylor College of Medicine Houston Texas 77030 —
R and R Eye Research, LLC San Antonio Texas 78229 —
University of Utah - Moran Eye Center Salt Lake City Utah 84132 —
Virginia Eye Institute Richmond Virginia 23226 —
Virginia Mason Medical Center Seattle Washington 98101 —
NY Eye Surgeons Seattle Washington 98133 —
University of Wisconsin - Madison Madison Wisconsin 53705 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03134196, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 7, 2025 · Synced Oct 18, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03134196 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →