Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors
Public ClinicalTrials.gov record NCT03138889. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Open-Label, Multicenter Study to Investigate the Safety and Preliminary Efficacy of Combined Bempegaldesleukin (NKTR-214) and Pembrolizumab With or Without Chemotherapy in Patients With Locally Advanced or Metastatic Solid Tumors
Study identification
- NCT ID
- NCT03138889
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Nektar Therapeutics
- Industry
- Enrollment
- 162 participants
Conditions and interventions
Conditions
Interventions
- Atezolizumab Drug
- Carboplatin Drug
- Cisplatin Drug
- NKTR-214 Drug
- Nab paclitaxel Drug
- Paclitaxel Drug
- Pembrolizumab Drug
- Pemetrexed Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 8, 2017
- Primary completion
- Jul 4, 2022
- Completion
- Aug 23, 2022
- Last update posted
- Mar 9, 2023
2017 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 20
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Highlands Oncology Group, PA - North Hills | Fayetteville | Arkansas | 72703 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Augusta University - Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70816 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Park Nicollet - Frauenshuh Cancer Center | Saint Louis Park | Minnesota | 55426 | — |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63156 | — |
| St. Vincent Frontier Cancer Center | Billings | Montana | 59101 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Comprehensive Cancer Centers of Nevada (CCCN) - Central Valley | Las Vegas | Nevada | 89169 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| New York University Langone Medical Center | New York | New York | 10016 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Duke Clinical Research Institute | Durham | North Carolina | 27705 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| West Cancer Center | Germantown | Tennessee | 38138 | — |
| Sarah Cannon Research Institute (SCRI) (The SCRI Oncology Research Consortium) | Nashville | Tennessee | 37203 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Inova Melanoma and Skin Cancer Center | Fairfax | Virginia | 22031 | — |
| Blue Ridge Cancer Care | Roanoke | Virginia | 24153 | — |
| Northwest Medical Specialties | Tacoma | Washington | 98405 | — |
| Froedtert & the Medical College of Wisconsin Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03138889, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 9, 2023 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03138889 live on ClinicalTrials.gov.