ClinicalTrials.gov record
Mupirocin-Iodophor ICU Decolonization Swap Out Trial
ClinicalTrials.gov ID: NCT03140423
Public ClinicalTrials.gov record NCT03140423. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Cluster-randomized Non-inferiority Trial Comparing Mupirocin vs Iodophor for Nasal Decolonization of ICU Patients to Assess Impact on S. Aureus Clinical Cultures and All-cause Bloodstream Infection During Routine Chlorhexidine Bathing
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Swap Out Trial is a cluster randomized controlled trial of HCA hospitals, evaluating the non-inferiority of two decolonization regimens: Arm 1 Routine Care: ICU nasal decolonization with mupirocin twice daily for 5 days in the context of chlorhexidine for daily bathing; Arm 2 Intervention: ICU nasal decolonization with iodophor twice daily for 5 days in the context of chlorhexidine for daily bathing Note: that enrolled "subjects" represents 137 individual HCA Hospitals (representing \~235 ICUs) that have been randomized.
Study identification
- NCT ID
- NCT03140423
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 353,323 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2017 (Actual)
- Primary completion
- Nov 6, 2023 (Actual)
- Completion
- Nov 6, 2023 (Actual)
- Last update posted
- Mar 30, 2025
2017 – 2023
United States locations
- U.S. sites
- 137
- U.S. states
- 19
- U.S. cities
- 106
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Riverside Community Hospital | Riverside | California | 92501 | — |
| Regional Medical Center of San Jose | San Jose | California | 95116 | — |
| Good Samaritan Hospital | San Jose | California | 95124 | — |
| Los Robles Regional Medical Center | Thousand Oaks | California | 91360 | — |
| West Hills Hospital & Medical Center | West Hills | California | 91307 | — |
| The Medical Center of Aurora | Aurora | Colorado | 80012 | — |
| Swedish Medical Center | Denver | Colorado | 80113 | — |
| Sky Ridge Medical Center | Denver | Colorado | 80124 | — |
| Presbyterian St. Luke's Medical Center | Denver | Colorado | 80218 | — |
| Rose Medical Center | Denver | Colorado | 80220 | — |
| North Suburban Medical Center - JV | Thornton | Colorado | 80229 | — |
| JFK Medical Center | Atlantis | Florida | 33462 | — |
| Aventura Hospital | Aventura | Florida | 33180 | — |
| Blake Medical Center | Bradenton | Florida | 34209 | — |
| Brandon Regional | Brandon | Florida | 33511 | — |
| Oak Hill Hospital | Brooksville | Florida | 34613 | — |
| Englewood Community Hospital | Englewood | Florida | 34223 | — |
| Fort Walton Medical Center | Fort Walton Beach | Florida | 32547 | — |
| Lawnwood Regional Medical Center | Ft. Pierce | Florida | 34950 | — |
| North Florida Regional Medical Center | Gainesville | Florida | 32605 | — |
| Regional Medical Center Bayonet Point | Hudson | Florida | 34667 | — |
| Memorial Hospital Jacksonville | Jacksonville | Florida | 32216 | — |
| Osceola Regional Medical Center | Kissimmee | Florida | 34741 | — |
| Poinciana Medical Center | Kissimmee | Florida | 34758 | — |
| Lake City Medical Center | Lake City | Florida | 32055 | — |
| Largo Medical Center | Largo | Florida | 33770 | — |
| Palms West Hospital | Loxahatchee Groves | Florida | 33470 | — |
| Northwest Medical Center | Margate | Florida | 33063 | — |
| Mercy Hospital | Miami | Florida | 33133 | — |
| Kendall Regional Medical Center | Miami | Florida | 33175 | — |
| Twin Cities Hospital | Niceville | Florida | 32578 | — |
| Ocala Regional Medical Center | Ocala | Florida | 34471 | — |
| West Marion Community Hospital | Ocala | Florida | 34474 | — |
| Raulerson Hospital | Okeechobee | Florida | 34972 | — |
| Orange Park Medical Center | Orange Park | Florida | 32073 | — |
| Gulf Coast Medical Center | Panama City | Florida | 32405 | — |
| West Florida Hospital | Pensacola | Florida | 32514 | — |
| Plantation General Hospital | Plantation | Florida | 33317 | — |
| Westside Regional Medical Center | Plantation | Florida | 33324 | — |
| Fawcett Memorial Hospital | Port Charlotte | Florida | 33952 | — |
| St. Lucie Medical Center | Port Saint Lucie | Florida | 34952 | — |
| Central Florida Regional Hospital | Sanford | Florida | 32771 | — |
| Doctor's Hospital Sarasota | Sarasota | Florida | 34233 | — |
| Northside Hospital | St. Petersburg | Florida | 33709 | — |
| St. Petersburg General Hospital | St. Petersburg | Florida | 33710 | — |
| South Bay Hospital | Sun City Center | Florida | 33573 | — |
| Capital Regional Medical Center | Tallahassee | Florida | 32308 | — |
| University Hospital & Medical Center | Tamarac | Florida | 33321 | — |
| Medical Center of Trinity | Trinity | Florida | 34655 | — |
| JFK Medical Center - North Campus | West Palm Beach | Florida | 33407 | — |
| Doctor's Hospital Augusta | Augusta | Georgia | 30909 | — |
| Cartersville Medical Center | Cartersville | Georgia | 30120 | — |
| Fairview Park | Dublin | Georgia | 31021 | — |
| Coliseum Medical Centers - Main | Macon | Georgia | 31217 | — |
| Coliseum Medical Centers - Northside | Macon | Georgia | 31217 | — |
| Redmond Regional Medical Center | Rome | Georgia | 30165 | — |
| Eastside Medical Center | Snellville | Georgia | 30078 | — |
| West Valley Medical Center | Caldwell | Idaho | 83605 | — |
| Eastern Idaho Regional | Idaho Falls | Idaho | 83404 | — |
| Terre Haute Regional Hospital | Terre Haute | Indiana | 47802 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Overland Park Regional Medical Center | Overland Park | Kansas | 66215 | — |
| Wesley Medical Center | Wichita | Kansas | 67214 | — |
| Wesley Woodlawn Hospital | Wichita | Kansas | 67220 | — |
| Greenview Regional Hospital | Bowling Green | Kentucky | 42104 | — |
| Rapides Regional Medical Center | Alexandria | Louisiana | 71301 | — |
| Lakeview Regional Medical Center | Covington | Louisiana | 70433 | — |
| Tulane University Hospital & Clinic | New Orleans | Louisiana | 70112 | — |
| Garden Park Medical Center | Gulfport | Mississippi | 39503 | — |
| Belton Regional Medical Center | Belton | Missouri | 64012 | — |
| Centerpoint Medical Center | Independence | Missouri | 64057 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Lee's Summit Medical Center | Lee's Summit | Missouri | 64063 | — |
| Sunrise Hospital & Medical Center | Las Vegas | Nevada | 89109 | — |
| Mountainview Hospital - Vegas | Las Vegas | Nevada | 89128 | — |
| Southern Hills Hospital - Vegas | Las Vegas | Nevada | 89148 | — |
| Parkland Medical Center | Derry | New Hampshire | 03038 | — |
| Portsmouth Regional Hospital | Portsmouth | New Hampshire | 03801 | — |
| Spotsylvania Regional Medical Center | Fredericksburg | Pennsylvania | 22408 | — |
| Trident Regional Medical Center | Charleston | South Carolina | 29406 | — |
| Grand Strand Regional Medical Center | Myrtle Beach | South Carolina | 29572 | — |
| Summerville Medical Center | Summerville | South Carolina | 29485 | — |
| Colleton Medical Center | Walterboro | South Carolina | 29488 | — |
| Parkridge Medical Center | Chattanooga | Tennessee | 37404 | — |
| Parkridge East Hospital | Chattanooga | Tennessee | 37412 | — |
| Hendersonville Medical Center | Hendersonville | Tennessee | 37075 | — |
| Summit Medical Center | Hermitage | Tennessee | 37076 | — |
| Stonecrest Medical Center | Nashville | Tennessee | 37167 | — |
| Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Skyline Medical Center | Nashville | Tennessee | 37207 | — |
| Southern Hills Medical Center | Nashville | Tennessee | 37211 | — |
| Medical Center of Arlington | Arlington | Texas | 76015 | — |
| South Austin Hospital | Austin | Texas | 78704 | — |
| North Austin Medical Center | Austin | Texas | 78758 | — |
| Valley Regional Medical Center | Brownsville | Texas | 78526 | — |
| Conroe Regional Medical Center | Conroe | Texas | 77304 | — |
| Corpus Christi Medical Center - Doctor's | Corpus Christi | Texas | 78411 | — |
| Corpus Christi Medical Center - The Heart Hospital | Corpus Christi | Texas | 78412 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Denton Regional Medical Center | Denton | Texas | 76210 | — |
| Las Palmas Medical Center | El Paso | Texas | 79902 | — |
| Del Sol Medical Center | El Paso | Texas | 79925 | — |
| Plaza Medical Center of Fort Worth | Fort Worth | Texas | 76104 | — |
| East Houston Regional Medical Center | Houston | Texas | 77015 | — |
| West Houston Medical Center | Houston | Texas | 77082 | — |
| Las Colinas Medical Center | Irving | Texas | 75039 | — |
| Kingwood Medical Center | Kingwood | Texas | 77339 | — |
| Medical Center of Lewisville | Lewisville | Texas | 75057 | — |
| Rio Grande Regional Hospital | McAllen | Texas | 78503 | — |
| Medical Center of McKinney | McKinney | Texas | 75069 | — |
| North Hills Hospital | North Richland Hills | Texas | 76180 | — |
| Bayshore Medical Center | Pasadena | Texas | 77504 | — |
| Medical Center of Plano | Plano | Texas | 75075 | — |
| Round Rock Hospital | Round Rock | Texas | 78681 | — |
| Metropolitan Methodist Hospital | San Antonio | Texas | 78212 | — |
| Methodist Hospital | San Antonio | Texas | 78229 | — |
| Methodist Specialty & Transplant Hospital | San Antonio | Texas | 78229 | — |
| Methodist Stone Oak Hospital | San Antonio | Texas | 78229 | — |
| Methodist Texsan Hospital | San Antonio | Texas | 78229 | — |
| Northeast Methodist Hospital | San Antonio | Texas | 78229 | — |
| Mainland Medical Center | Texas City | Texas | 77591 | — |
| Clearlake Regional Medical Center | Webster | Texas | 77598 | — |
| Lakeview Hospital | Bountiful | Utah | 84010 | — |
| Ogden Regional Medical Center | Ogden | Utah | 84405 | — |
| Timpanogos Regional Medical Center | Orem | Utah | 84057 | — |
| Mountain View Hospital - Utah | Payson | Utah | 84651 | — |
| LewisGale Hospital - Montgomery | Blacksburg | Virginia | 24060 | — |
| John Randolph Medical Center | Hopewell | Virginia | 23860 | — |
| LewisGale Hospital - Alleghany | Low Moor | Virginia | 24457 | — |
| LewisGale Hospital - Pulaski | Pulaski | Virginia | 24301 | — |
| Reston Hospital | Reston | Virginia | 20190 | — |
| Henrico Doctors' Hospital - Retreat Campus | Richmond | Virginia | 23220 | — |
| CJW Medical Center (Chippenham Campus) | Richmond | Virginia | 23225 | — |
| CJW Medical Center (Johnston Willis Campus) | Richmond | Virginia | 23225 | — |
| Henrico Doctors' Hospital - Forest Campus | Richmond | Virginia | 23229 | — |
| Henrico Doctors' Hospital - Parham Campus | Richmond | Virginia | 23294 | — |
| LewisGale Medical Center | Salem | Virginia | 24153 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03140423, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2025 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03140423 live on ClinicalTrials.gov.