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Completed Phase 1 Interventional

Study of AMV564 in Patients With AML

ClinicalTrials.gov ID: NCT03144245

Public ClinicalTrials.gov record NCT03144245. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 3:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, First in Human, Open Label, Dose Escalation Study of AMV564, a CD33 x CD3 Tandem Diabody in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Study identification

NCT ID
NCT03144245
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Amphivena Therapeutics, Inc.
Industry
Enrollment
53 participants

Conditions and interventions

Interventions

  • AMV564 Biological
  • AMV564 in combination with pembrolizumab Combination Product

Biological · Combination Product

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 19, 2017
Primary completion
Jul 20, 2020
Completion
Nov 4, 2020
Last update posted
Oct 11, 2021

2017 – 2020

United States locations

U.S. sites
10
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
University of California, San Francisco San Francisco California 94143
Northwestern Chicago Illinois 60611
Johns Hopkins University Baltimore Maryland 21287
Washington University School of Medicine St Louis Missouri 63110
New York Medical College Hawthorne New York 10532
Weill Cornell Medical College, The New York Presbyterian Hospital New York New York 10021
The Ohio State University Comprehensive Cancer Center Columbus Ohio 43210
University of Pennsylvania Philadelphia Pennsylvania 19104
MD Anderson Cancer Center, The University of Texas Houston Texas 70030-4009
Fred Hutchinson Cancer Research Seattle Washington 98109-1024

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03144245, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 11, 2021 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03144245 live on ClinicalTrials.gov.

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