Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

A Study of Itacitinib in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Participants With Myelofibrosis

ClinicalTrials.gov ID: NCT03144687

Public ClinicalTrials.gov record NCT03144687. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 3:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Phase 2 Study of Itacitinib (INCB039110) in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Subjects With Myelofibrosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of itacitinib combined with low-dose ruxolitinib or itacitinib alone in participants with myelofibrosis (MF).

Study identification

NCT ID
NCT03144687
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Incyte Corporation
Industry
Enrollment
23 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 26, 2018 (Actual)
Primary completion
Mar 14, 2020 (Actual)
Completion
Jun 1, 2021 (Actual)
Last update posted
Jun 16, 2022

2018 – 2021

United States locations

U.S. sites
19
U.S. states
14
U.S. cities
19
Facility City State ZIP Site status
Arizona Oncology Associates Tempe Arizona 85284 —
UC Irvine Medical Center Orange California 92868 —
Anschutz Cancer Pavilion - University Of Colorado Aurora Colorado 80045 —
Rocky Mountain Cancer Center Colorado Springs Colorado 80907 —
Rocky Mountain Cancer Center Denver Colorado 80218 —
Norwalk Hospital Norwalk Connecticut 06856 —
Parkview Research Center Fort Wayne Indiana 46845 —
University of Michigan Cancer Center Ann Arbor Michigan 48109 —
Providence Cancer Center Southfield Michigan 48075 —
Nebraska Cancer Specialist Omaha Nebraska 68124 —
University Of New Mexico Cancer Center Albuquerque New Mexico 87102 —
Duke University Medical Center Durham North Carolina 27710 —
Cleveland Clinic Cleveland Ohio 44195 —
Willamette Valley Cancer Institute Eugene Oregon 97401 —
Consultants in Medical Oncology and Hematology, PC Broomall Pennsylvania 19008 —
Texas Oncology - Round Rock Cancer Center Round Rock Texas 78681 —
Texas Oncology San Antonio San Antonio Texas 78240 —
Texas Oncology - Tyler Tyler Texas 75702 —
University of Virginia Charlottesville Virginia 22908 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03144687, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 16, 2022 · Synced Oct 17, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03144687 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →