A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)
Public ClinicalTrials.gov record NCT03148418. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multicenter Extension and Long-Term Observational Study in Patients Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an open-label, multicenter, non-randomized extension and long-term observational study. Participants receiving atezolizumab monotherapy or atezolizumab combined with other agent(s) or comparator agent(s) in a Genentech or Roche-sponsored study (the parent study) and who continue to receive study treatment at the time of the parent-study closure and do not have access to the study treatment locally are eligible for continued treatment in the extension study. Dosing regimen for a given participant and indication will be the same or equivalent to the respective parent study protocol. Study treatment in the extension study can continue until disease progression or beyond if the patient continues to derive clinical benefit as judged by the investigator and if allowed by the parent study or local prescribing information until death; withdrawal of study consent; unacceptable toxicity; pregnancy; patient non-compliance; or study termination by the Sponsor, whichever occurs first.
Study identification
- NCT ID
- NCT03148418
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 382 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 19, 2017
- Primary completion
- Dec 30, 2026
- Completion
- Dec 30, 2026
- Last update posted
- Jul 9, 2026
2017 – 2026
United States locations
- U.S. sites
- 44
- U.S. states
- 25
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HonorHealth Research Institute ? Bisgrove | Scottsdale | Arizona | 85258 | — |
| Angeles Clinic & Rsch Inst | Los Angeles | California | 90025 | — |
| UCLA | Los Angeles | California | 90095 | — |
| Kaiser Permanente - San Diego (Zion Ave) | San Marcos | California | 92078 | — |
| University Of Colorado | Aurora | Colorado | 80045 | — |
| Rocky Mountain Cancer Ctr - Denver (Williams) | Denver | Colorado | 80218 | — |
| Smilow Cancer Hospital at Yale New Haven | New Haven | Connecticut | 06510 | — |
| Georgetown University Medical Center Lombardi Cancer Center | Washington D.C. | District of Columbia | 20057 | — |
| Florida Cancer Specialists - Fort Myers (Broadway) | Fort Myers | Florida | 33901 | — |
| Hematology Oncology Associates of the Treasure Coast | Port Saint Lucie | Florida | 34952 | — |
| Florida Cancer Specialists. | St. Petersburg | Florida | 33705 | — |
| H. Lee Moffitt Cancer Center and Research Inst. | Tampa | Florida | 33612 | — |
| Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital | Marietta | Georgia | 30060 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612-3244 | — |
| University Of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Illinois Cancer Care | Peoria | Illinois | 61615 | — |
| New England Cancer Specialists | Westbrook | Maine | 04092 | — |
| Johns Hopkins Univ Med Center | Baltimore | Maryland | 21231 | — |
| Maryland Oncology Hematology, P.A. | Columbia | Maryland | 21044 | — |
| Massachusetts General Hospital. | Boston | Massachusetts | 02114 | — |
| Beth Israel Medical Center | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Inst. | Boston | Massachusetts | 02215 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| US oncology research at Minnesota Oncology | Saint Louis Park | Minnesota | 55416 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Comprehensive Cancer Centers of Nevada - Eastern Avenue | Las Vegas | Nevada | 89169 | — |
| Summit Medical Center | Florham Park | New Jersey | 07932 | — |
| New York Oncology Hematology, P.C. | Albany | New York | 12206 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| Carolina BioOncology Institute, PLCC | Huntersville | North Carolina | 28078 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Oncology Associates of Oregon, P.C | Eugene | Oregon | 97401 | — |
| Northwest Cancer Specialists - Portland (N Broadway) | Portland | Oregon | 97227 | — |
| Penn State Hershey Cancer Institute | Hershey | Pennsylvania | 17033 | — |
| Allegheny Cancer Center | Pittsburgh | Pennsylvania | 15212 | — |
| Sarah Cannon Res Inst | Nashville | Tennessee | 37203 | — |
| Texas Oncology - DFW | Dallas | Texas | 75246 | — |
| Tyler Cancer Center | Tyler | Texas | 75702 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Blue Ridge Cancer Care | Roanoke | Virginia | 24014 | — |
| University of Washington Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
| Northwest Medical Specialties | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 126 non-U.S. sites.
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About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03148418, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 9, 2026 · Synced Jul 28, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03148418 live on ClinicalTrials.gov.