ClinicalTrials.gov record
Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer
ClinicalTrials.gov ID: NCT03155997
Public ClinicalTrials.gov record NCT03155997. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open-Label, Phase 3 Study of Abemaciclib Combined With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone in Patients With High Risk, Node Positive, Early Stage, Hormone Receptor Positive, Human Epidermal Receptor 2 Negative, Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of the study drug abemaciclib in participants with high risk, node positive, early stage, hormone receptor positive (HR+), human epidermal receptor 2 negative (HER2-), breast cancer.
Study identification
- NCT ID
- NCT03155997
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 5,637 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2017 (Actual)
- Primary completion
- Mar 16, 2020 (Actual)
- Completion
- May 2029 (Estimated)
- Last update posted
- Apr 24, 2026
2017 – 2029
United States locations
- U.S. sites
- 162
- U.S. states
- 38
- U.S. cities
- 107
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 32594 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | — |
| Arizona Oncology Associates, P.C. - HOPE | Goodyear | Arizona | 85395 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | — |
| The University of Arizona Cancer Center | Tucson | Arizona | 85719 | — |
| Yuma Regional Cancer Center | Yuma | Arizona | 85364 | — |
| St. Bernards Medical Center | Jonesboro | Arkansas | 72401 | — |
| Highlands Oncology Group | Springdale | Arkansas | 72762 | — |
| Beverly Hills Cancer Center | Beverly Hills | California | 90211 | — |
| Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center | Burbank | California | 91505 | — |
| City of Hope National Medical Center | Duarte | California | 91010-0269 | — |
| California Cancer Associates Research and Excellence | Fresno | California | 93720 | — |
| Kaiser Permanente | Harbor City | California | 92505 | — |
| Loma Linda University School of Medicine | Loma Linda | California | 92354 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Pacific Cancer Care | Monterey | California | 93940 | — |
| St. Joseph Hospital | Orange | California | 92868 | — |
| University of California Davis (UC Davis) Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| UCSF Medical Center at Mission Bay | San Francisco | California | 94158 | — |
| California Cancer Associates in Research and Excellence | San Marcos | California | 92069 | — |
| Dignity Health Dominican Oncology and Hematology | Santa Cruz | California | 95065 | — |
| Kaiser Permanente | Vallejo | California | 94589 | — |
| USO-Rocky Mountain Cancer Center | Boulder | Colorado | 80303 | — |
| USO-Rocky Mountain Cancer Center | Thornton | Colorado | 80260 | — |
| Yale-New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Florida Cancer Specialists - South | Fort Myers | Florida | 37203 | — |
| University of Florida College of Medicine | Gainesville | Florida | 32610 | — |
| Millennium Oncology - Hollywood | Hollywood | Florida | 33024 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | — |
| Cancer Specialists of North Florida | Jacksonville | Florida | 32256 | — |
| Florida Cancer Specialists - North | Lecanto | Florida | 34461 | — |
| Ocala Oncology, P.A. | Ocala | Florida | 34474 | — |
| Tallahassee Memorial Cancer Center | Tallahassee | Florida | 32308 | — |
| Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center | Tampa | Florida | 33612 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital | Marietta | Georgia | 30060 | — |
| Summit Cancer Care DBA Candler Medical Oncology Practice | Savannah | Georgia | 31405 | — |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813 | — |
| John H. Stroger Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Edward Cancer Center | Naperville | Illinois | 60540 | — |
| Quincy Medical Group | Quincy | Illinois | 62301 | — |
| Franciscan St. Francis Health | Indianapolis | Indiana | 46237 | — |
| Community Howard Oncology Center | Kokomo | Indiana | 46902 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| Univ of Louisville School of Medicine | Louisville | Kentucky | 40202 | — |
| Mary Bird Perkins Cancer Center - Baton Rouge | Baton Rouge | Louisiana | 70817 | — |
| Terrebonne General Medical Center | Houma | Louisiana | 70360 | — |
| Cancer Care of Maine | Brewer | Maine | 04412 | — |
| New England Cancer Specialists - Kennebunk | Kennebunk | Maine | 04043 | — |
| Central Maine Medical Center | Lewiston | Maine | 04240 | — |
| Meritus John Marsh Cancer Center | Hagerstown | Maryland | 21742 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Reliant Medical Group, Inc. | Worcester | Massachusetts | 01606 | — |
| Mayo Clinic in Rochester, Minnesota | Rochester | Minnesota | 55905 | — |
| Jackson Oncology Associates PLLC | Jackson | Mississippi | 39202 | — |
| HCA Midwest Kansas City, MidAmerica Division, Inc. | Kansas City | Missouri | 37203 | — |
| Cancer Alliance of Nebraska | Omaha | Nebraska | 68106 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Tennessee Cancer Specialists | Omaha | Nebraska | 68130 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Memorial Sloan Kettering - Basking Ridge | Basking Ridge | New Jersey | 07920 | — |
| Summit Medical Group Cancer Center | Florham Park | New Jersey | 07932 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| The Valley Hospital, Inc. | Paramus | New Jersey | 07652 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| Broome Oncology | Binghamton | New York | 13905 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| Vassar Brothers Medical Center | Poughkeepsie | New York | 12601 | — |
| SUNY At Stony Brook | Stony Brook | New York | 11794 | — |
| White Plains Hospital | White Plains | New York | 10601 | — |
| WakeMed Cancer Care - Waverly Hematology & Medical Oncology | Cary | North Carolina | 27518 | — |
| Margaret R. Pardee Memorial Hospital | Hendersonville | North Carolina | 28739 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Columbus Community Clinical Oncology Program | Columbus | Ohio | 43215 | — |
| Asante Rogue Regional Medical Center | Medford | Oregon | 97504 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Abington Medical Specialists | Abington | Pennsylvania | 19001 | — |
| St. Luke's Hospital & Health Network | Bethlehem | Pennsylvania | 18015 | — |
| Albert Einstein Healthcare Network | Philadelphia | Pennsylvania | 19141 | — |
| AHN Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| NSABP Foundation | Pittsburgh | Pennsylvania | 15213 | — |
| PinnacleHealth Cancer Institute | Pittsburgh | Pennsylvania | 15213 | — |
| Univ of Pittsburgh Cancer Inst. (UPCI) | Pittsburgh | Pennsylvania | 15213 | — |
| WellSpan Health/York Cancer Center Oncology Research | York | Pennsylvania | 17403 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29502 | — |
| St Francis Cancer Center | Greenville | South Carolina | 29607 | — |
| Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| Sanford USD Medical Center | Sioux Falls | South Dakota | 57105 | — |
| Erlanger Health System | Chattanooga | Tennessee | 37403 | — |
| Chattanooga Research and Medicine | Chattanooga | Tennessee | 37404 | — |
| The West Clinic, PLLC dba West Cancer Center | Germantown | Tennessee | 38138 | — |
| Urology Associates of Kingsport | Kingsport | Tennessee | 37660 | — |
| Tennessee Cancer Specialists | Knoxville | Tennessee | 37909 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| Baptist Cancer Center | Memphis | Tennessee | 38120 | — |
| Florida Cancer Specialists | Nashville | Tennessee | 37203 | — |
| Sarah Cannon Cancer Center | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology Nashville | Nashville | Tennessee | 37203 | — |
| Texas Oncology Cancer Care and Research Center | Austin | Texas | 78731 | — |
| Texas Oncology-Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390 | — |
| Texas Oncology Fort Worth | Fort Worth | Texas | 76104 | — |
| Oncology Consultants, P.A. | Houston | Texas | 77030 | — |
| Texas Oncology P.A. | Lewisville | Texas | 75056 | — |
| University of Texas Health Science Center - San Antonio | San Antonio | Texas | 78229 | — |
| Arizona Oncology Associates, P.C. - HOPE | The Woodlands | Texas | 77380 | — |
| Comprehensive Cancer Centers of Nevada | The Woodlands | Texas | 77380 | — |
| Illinois Cancer Specialists | The Woodlands | Texas | 77380 | — |
| Miami Cancer Institute at Baptist Health, Inc. | The Woodlands | Texas | 77380 | — |
| Minnesota Oncology/Hematology PA | The Woodlands | Texas | 77380 | — |
| Northwest Cancer Specialists PC | The Woodlands | Texas | 77380 | — |
| Oncology and Hematology Associates of Southwest Virginia Inc | The Woodlands | Texas | 77380 | — |
| Oncology Hematology Care Inc | The Woodlands | Texas | 77380 | — |
| Oncology Hematology West | The Woodlands | Texas | 77380 | — |
| Sansum Clinic | The Woodlands | Texas | 77380 | — |
| Shenandoah Oncology, P.C. | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Dallas Presbyterian Hospital | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Denison | The Woodlands | Texas | 77380 | — |
| Texas Oncology - McAllen | The Woodlands | Texas | 77380 | — |
| Texas Oncology - McKinney | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Medical City Dallas | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Methodist Dallas Cancer Center | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Paris | The Woodlands | Texas | 77380 | — |
| Texas Oncology - San Antonio Medical Center | The Woodlands | Texas | 77380 | — |
| Texas Oncology - The Woodlands | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Tyler | The Woodlands | Texas | 77380 | — |
| Texas Oncology - West Texas | The Woodlands | Texas | 77380 | — |
| Texas Oncology Cancer Care and Research Center | The Woodlands | Texas | 77380 | — |
| Texas Oncology Denton | The Woodlands | Texas | 77380 | — |
| Texas Oncology Fort Worth | The Woodlands | Texas | 77380 | — |
| Texas Oncology P.A. | The Woodlands | Texas | 77380 | — |
| Texas Oncology- Mesquite | The Woodlands | Texas | 77380 | — |
| Texas Oncology-Arlington South | The Woodlands | Texas | 77380 | — |
| Texas Oncology-Baylor Charles A. Sammons Cancer Center | The Woodlands | Texas | 77380 | — |
| Texas Oncology-Deke Slayton Cancer Center | The Woodlands | Texas | 77380 | — |
| Texas Oncology-Plano East | The Woodlands | Texas | 77380 | — |
| Texas Oncology-Plano West | The Woodlands | Texas | 77380 | — |
| US Oncology | The Woodlands | Texas | 77380 | — |
| USO - Texas Oncology, P. A. | The Woodlands | Texas | 77380 | — |
| USO-Maryland Oncology Hematology, P.A. | The Woodlands | Texas | 77380 | — |
| USO-New York Oncology Hematology, P.C | The Woodlands | Texas | 77380 | — |
| USO-Rocky Mountain Cancer Center | The Woodlands | Texas | 77380 | — |
| USO-Southern Cancer Center, P.C. | The Woodlands | Texas | 77380 | — |
| USO-Virginia Oncology Associates | The Woodlands | Texas | 77380 | — |
| Virginia Cancer Specialists | The Woodlands | Texas | 77380 | — |
| Willamette Valley Cancer Institute & Research Ctr. | The Woodlands | Texas | 77380 | — |
| Texas Oncology - Paris | Tyler | Texas | 75702 | — |
| Texas Oncology - Tyler | Tyler | Texas | 75702 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| The University of Vermont Medical Center Inc. | Burlington | Vermont | 05401 | — |
| Hematology Oncology Associates of Fredericksburg Inc. | Fredericksburg | Virginia | 22408 | — |
| Virginia Commonwealth University (VCU) Medical Center | Richmond | Virginia | 23219 | — |
| MultiCare Regional Cancer Center - Auburn | Auburn | Washington | 98001 | — |
| Swedish Medical Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 457 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03155997, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 24, 2026 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03155997 live on ClinicalTrials.gov.