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Completed Phase 3 Interventional Results available

Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma.

ClinicalTrials.gov ID: NCT03158688

Public ClinicalTrials.gov record NCT03158688. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 4:59 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Open-label, Phase 3 Study Comparing Carfilzomib, Dexamethasone, and Daratumumab to Carfilzomib and Dexamethasone for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Compare carfizomib, dexamethasone, and daratumumab (KdD) to Carfilzomib and dexamethasone (Kd) in terms of progression free survival (PFS) in participants with multiple myeloma who have relapsed after 1 to 3 prior therapies.

Study identification

NCT ID
NCT03158688
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Amgen
Industry
Enrollment
466 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 12, 2017
Primary completion
Jul 13, 2019
Completion
Apr 14, 2022
Last update posted
May 8, 2025

2017 – 2022

United States locations

U.S. sites
11
U.S. states
11
U.S. cities
11
Facility City State ZIP Site status
Lynn Cancer Center Boca Raton Regional Hospital, Lynn Cancer Institute Boca Raton Florida 33486
Emory University Winship Cancer Institute Atlanta Georgia 30322
University of Chicago Medical Center - Multiple Myeloma Research Consortium Chicago Illinois 60637-6613
Fort Wayne Medical Oncology and Hematology Fort Wayne Indiana 46845
Hattiesburg Clinic Hematology/Oncology Hattiesburg Mississippi 39401
Hackensack University Medical Center Hackensack New Jersey 07601
New York Presbyterian Hospital, Weill Cornell Medical College New York New York 10021
Levine Cancer Institute Charlotte North Carolina 28204
Gabrail Cancer Center, LLC Dover Ohio 44622
Charleston Oncology Charleston South Carolina 29414
Baylor Charles A Sammons Cancer Center at Dallas Dallas Texas 75246

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 102 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03158688, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 8, 2025 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03158688 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →