A Study of the Safety and Effectiveness of Benralizumab to Treat Patients With Severe Uncontrolled Asthma.
Public ClinicalTrials.gov record NCT03170271. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Parallel Group, Placebo Controlled, Phase 3b Study to Evaluate the Safety and Efficacy of Benralizumab 30 mg sc in Patients With Severe Asthma Uncontrolled on Standard of Care Treatment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to investigate the effect of benralizumab on the rate of asthma exacerbations, patient reported quality of life and lung function during the 24-week treatment in patients with uncontrolled, severe asthma with an eosinophilic phenotype. A subset of patients will be assessed for their ongoing chronic rhinosinusitis with nasal polyps. The study design has been updated to include a 56-week open label ANDHI in Practice (ANDHI IP) sub study upon the completion of the 24-week double-blind period of the ANDHI study.
Study identification
- NCT ID
- NCT03170271
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 660 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 7, 2017 (Actual)
- Primary completion
- Sep 25, 2019 (Actual)
- Completion
- Oct 21, 2020 (Actual)
- Last update posted
- Nov 1, 2021
2017 – 2020
United States locations
- U.S. sites
- 100
- U.S. states
- 37
- U.S. cities
- 90
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35209 | — |
| Research Site | Tucson | Arizona | 85724 | — |
| Research Site | Little Rock | Arkansas | 72209 | — |
| Research Site | Bakersfield | California | 93301 | — |
| Research Site | Encinitas | California | 92024 | — |
| Research Site | Long Beach | California | 90806 | — |
| Research Site | Los Angeles | California | 90025 | — |
| Research Site | Mission Viejo | California | 92691 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Riverside | California | 92506 | — |
| Research Site | San Diego | California | 92108 | — |
| Research Site | Stockton | California | 95207 | — |
| Research Site | Walnut Creek | California | 94598 | — |
| Research Site | Aurora | Colorado | 80045 | — |
| Research Site | New Haven | Connecticut | 06519 | — |
| Research Site | Waterbury | Connecticut | 06708 | — |
| Research Site | Clearwater | Florida | 33765 | — |
| Research Site | Jacksonville | Florida | 32099 | — |
| Research Site | Kissimmee | Florida | 34741 | — |
| Research Site | Miami | Florida | 33126 | — |
| Research Site | Miami | Florida | 33173 | — |
| Research Site | Winter Park | Florida | 32789 | — |
| Research Site | Albany | Georgia | 31707 | — |
| Research Site | Savannah | Georgia | 31406 | — |
| Research Site | Peoria | Illinois | 61602 | — |
| Research Site | South Bend | Indiana | 46617 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | West Des Moines | Iowa | 50266 | — |
| Research Site | Lakeside Park | Kentucky | 41017 | — |
| Research Site | Owensboro | Kentucky | 42301 | — |
| Research Site | Shreveport | Louisiana | 71106 | — |
| Research Site | Chevy Chase | Maryland | 20815 | — |
| Research Site | White Marsh | Maryland | 21162 | — |
| Research Site | North Dartmouth | Massachusetts | 02747 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | Ypsilanti | Michigan | 48197 | — |
| Research Site | Minneapolis | Minnesota | 55402 | — |
| Research Site | St Louis | Missouri | 63156 | — |
| Research Site | Missoula | Montana | 59808 | — |
| Research Site | Lincoln | Nebraska | 68510 | — |
| Research Site | Highland Park | New Jersey | 08904 | — |
| Research Site | Marlton | New Jersey | 08053 | — |
| Research Site | Northfield | New Jersey | 08225 | — |
| Research Site | Piscataway | New Jersey | 08854 | — |
| Research Site | Toms River | New Jersey | 08755 | — |
| Research Site | Verona | New Jersey | 07044 | — |
| Research Site | Albuquerque | New Mexico | 87106 | — |
| Research Site | New Hyde Park | New York | 11042 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | Rochester | New York | 14618 | — |
| Research Site | Staten Island | New York | 10305 | — |
| Research Site | Staten Island | New York | 10310 | — |
| Research Site | The Bronx | New York | 10459 | — |
| Research Site | Charlotte | North Carolina | 28277 | — |
| Research Site | Elizabeth City | North Carolina | 27909 | — |
| Research Site | Gastonia | North Carolina | 28054 | — |
| Research Site | Greenville | North Carolina | 27834 | — |
| Research Site | High Point | North Carolina | 27262 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Winston-Salem | North Carolina | 27157 | — |
| Research Site | Cincinnati | Ohio | 45231 | — |
| Research Site | Cincinnati | Ohio | 45242 | — |
| Research Site | Grove City | Ohio | 43123 | — |
| Research Site | Edmond | Oklahoma | 73034 | — |
| Research Site | Tulsa | Oklahoma | 74136 | — |
| Research Site | Clackamas | Oregon | 97015-5737 | — |
| Research Site | Philadelphia | Pennsylvania | 19107 | — |
| Research Site | Pittsburgh | Pennsylvania | 15213 | — |
| Research Site | Pittsburgh | Pennsylvania | 15241 | — |
| Research Site | Reading | Pennsylvania | 19610 | — |
| Research Site | Anderson | South Carolina | 29621 | — |
| Research Site | Gaffney | South Carolina | 29340 | — |
| Research Site | Greenville | South Carolina | 29607 | — |
| Research Site | Greenville | South Carolina | 29615 | — |
| Research Site | North Charleston | South Carolina | 29420-4211 | — |
| Research Site | Rock Hill | South Carolina | 29732 | — |
| Research Site | Sioux Falls | South Dakota | 57108 | — |
| Research Site | Franklin | Tennessee | 37067 | — |
| Research Site | Cypress | Texas | 77429 | — |
| Research Site | Dallas | Texas | 75225 | — |
| Research Site | Dallas | Texas | 75246 | — |
| Research Site | Fort Worth | Texas | 76109 | — |
| Research Site | Galveston | Texas | 77555 | — |
| Research Site | McKinney | Texas | 75069 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | San Antonio | Texas | 78249 | — |
| Research Site | San Antonio | Texas | 78251 | — |
| Research Site | Provo | Utah | 84604 | — |
| Research Site | South Burlington | Vermont | 05403 | — |
| Research Site | Abingdon | Virginia | 24210 | — |
| Research Site | Fairfax | Virginia | 22030 | — |
| Research Site | North Chesterfield | Virginia | 23225 | — |
| Research Site | Williamsburg | Virginia | 23188 | — |
| Research Site | Everett | Washington | 98208 | — |
| Research Site | Spokane | Washington | 99204 | — |
| Research Site | Tacoma | Washington | 98405 | — |
| Research Site | Madison | Wisconsin | 53792 | — |
| Research Site | Milwaukee | Wisconsin | 53226 | — |
| Research Site | Milwaukee | Wisconsin | 53228 | — |
| Research Site | West Allis | Wisconsin | 53227 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 113 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03170271, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 1, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03170271 live on ClinicalTrials.gov.