A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to <18 Years) With Type 2 Diabetes Mellitus
Public ClinicalTrials.gov record NCT03170518. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (≥10 to <18 Years) With Type 2 Diabetes Mellitus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the effect of canagliflozin relative to placebo on glycated hemoglobin (HbA1c) after 26 weeks of treatment, and to assess the overall safety and tolerability of canagliflozin.
Study identification
- NCT ID
- NCT03170518
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 171 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 10 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 21, 2017 (Actual)
- Primary completion
- Sep 20, 2023 (Actual)
- Completion
- Sep 20, 2023 (Actual)
- Last update posted
- Apr 25, 2025
2017 – 2023
United States locations
- U.S. sites
- 36
- U.S. states
- 18
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Childrens Hospital | Little Rock | Arkansas | 72202 | — |
| Center of Excellence for Diabetes and Endocrinology (CEDE) | Sacramento | California | 95821 | — |
| American Institute of Research | Whittier | California | 90603 | — |
| University of Colorado School of Medicine/Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Nemours DuPont Hospital for Children | Wilmington | Delaware | 19803 | — |
| TOPAZ Clinical Research | Apopka | Florida | 32703 | — |
| Columbus Clinical Services LLC | Miami | Florida | 33125 | — |
| Medical Research Center of Miami II Inc | Miami | Florida | 33134 | — |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | — |
| Nemours Children's Hospital/Endocrinology | Orlando | Florida | 32827 | — |
| Asclepes Research | Spring Hill | Florida | 34609 | — |
| Johns Hopkins All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Appalachian Clinical Research | Adairsville | Georgia | 30103 | — |
| Endocrine Consultants Research | Columbus | Georgia | 31904-4501 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Capital Diabetes and Endocrine Associates | Camp Springs | Maryland | 20746 | — |
| Floating Hospital For Children at Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Alas Viable Research | Henderson | Nevada | 89014 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| SUNY Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029-6500 | — |
| Carolinas Research Center, LLC | Charlotte | North Carolina | 28215 | — |
| WakeMed Clinical Research Institute | Raleigh | North Carolina | 27610 | — |
| PMG Research of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| Cleveland Clinic Center for Pediatric Endocrinology | Cleveland | Ohio | 44195 | — |
| Buckeye Health and Research, LLC | Columbus | Ohio | 43207 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| AM Diabetes & Endocrinology Center | Bartlett | Tennessee | 38133-4063 | — |
| LifeDoc Research, PLLC | Memphis | Tennessee | 38115 | — |
| Avant Research Associates, LLC | Austin | Texas | 78709 | — |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78411 | — |
| Amir Ali Hassan, MD, PA | Houston | Texas | 77089 | — |
| Sante Clinical Research | Kerrville | Texas | 78028 | — |
| Texas Institute for Kidney and Endocrine Disorders | Lufkin | Texas | 75904 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| MultiCare Health System | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 70 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03170518, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 25, 2025 · Synced Nov 7, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03170518 live on ClinicalTrials.gov.