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Completed Phase 1 Interventional Accepts healthy volunteers

A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin

ClinicalTrials.gov ID: NCT03174041

Public ClinicalTrials.gov record NCT03174041. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 12, 2026, 7:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 4-Part Phase 1 Study to Evaluate the Effect of GDC-0853 on the Pharmacokinetics of Midazolam, Rosuvastatin, and Simvastatin and the Effect of Itraconazole on the Pharmacokinetics of GDC-0853

Study identification

NCT ID
NCT03174041
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Genentech, Inc.
Industry
Enrollment
63 participants

Conditions and interventions

Interventions

  • GDC-0853 Drug
  • GDC-0853 and itraconazole Drug
  • Itraconazole Drug
  • Midazolam Drug
  • Midazolam and GDC-0853 Drug
  • Rosuvastatin Drug
  • Rosuvastatin and GDC-0853 Drug
  • Simvastatin Drug
  • Simvastatin and GDC-0853 Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 60 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 17, 2017
Primary completion
Jun 22, 2017
Completion
Jun 22, 2017
Last update posted
Sep 23, 2019

2017

United States locations

U.S. sites
3
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
Covance Research Unit - Daytona Daytona Beach Florida 32117
Covance Clinical Research Unit Inc.; Covance Gfi Research Evansville Indiana 47710
Covance Clinical Research Unit, Inc Madison Wisconsin 53704

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03174041, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 23, 2019 · Synced May 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03174041 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →