A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Public ClinicalTrials.gov record NCT03178149. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b, Multicenter, Dose Escalation, Evaluation of Safety and Tolerability of ASP7317 for Geographic Atrophy Secondary to Age-related Macular Degeneration
Study identification
- NCT ID
- NCT03178149
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Astellas Institute for Regenerative Medicine
- Industry
- Enrollment
- 42 participants
Conditions and interventions
Conditions
Interventions
- ASP7317 Drug
- tacrolimus Drug
- trimethoprim-sulfamethoxazole Drug
- Acyclovir Drug
- Nystatin Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2018
- Primary completion
- Jun 29, 2026
- Completion
- Jun 29, 2026
- Last update posted
- Jan 12, 2026
2018 – 2026
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Consultants of Arizona LTD, Retinal Research Institute | Phoenix | Arizona | 85053 | Withdrawn |
| Jules Stein Eye Institute | Los Angeles | California | 90095 | Recruiting |
| Stanford University Byers Eye Institute | Palo Alto | California | 94303 | Recruiting |
| Kaiser Permanente Riverside Medical Center | Riverside | California | 92505 | Recruiting |
| Retina Consultants of Southwest Florida & National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | Withdrawn |
| Retina Specialty Institute | Pensacola | Florida | 35203 | Recruiting |
| Emory University Eye Center | Atlanta | Georgia | 30322 | Recruiting |
| University Retina and Macula Associates | Oak Forest | Illinois | 60452 | Recruiting |
| Mass Eye and Ear Infirmary Ophthalmology Clinical Research Office | Boston | Massachusetts | 02114 | Withdrawn |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | Recruiting |
| University of Michigan Kellog Eye Center | Ann Arbor | Michigan | 48105 | Recruiting |
| Deep Blue Retina | Southaven | Mississippi | 38671 | Recruiting |
| NJ Retina | New Brunswick | New Jersey | 08901 | Withdrawn |
| Mid-Atlantic Retina | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Tennessee Retina, PC | Nashville | Tennessee | 37203 | Withdrawn |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | Recruiting |
| Valley Retina Institute | McAllen | Texas | 78503 | Completed |
| University of Washington | Seattle | Washington | 98104 | Withdrawn |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03178149, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 12, 2026 · Synced Jul 23, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03178149 live on ClinicalTrials.gov.