A Study of ALKS 5461 for Treatment Refractory Major Depressive Disorder (MDD)
Public ClinicalTrials.gov record NCT03188185. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b Efficacy and Safety Study of Adjunctive ALKS 5461 in Treatment Refractory Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy, safety, and tolerability of adjunctive ALKS 5461 in adults who have treatment refractory MDD.
Study identification
- NCT ID
- NCT03188185
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 278 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 12, 2017 (Actual)
- Primary completion
- Feb 26, 2020 (Actual)
- Completion
- Mar 5, 2020 (Actual)
- Last update posted
- Apr 8, 2021
2017 – 2020
United States locations
- U.S. sites
- 30
- U.S. states
- 15
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alkermes Investigational Site | Tucson | Arizona | 85712 | — |
| Alkermes Investigational Site | Little Rock | Arkansas | 72211 | — |
| Alkermes Investigational Site | Los Alamitos | California | 90720 | — |
| Alkermes Investigational Site | Oceanside | California | 92056 | — |
| Alkermes Investigational Site | Pico Rivera | California | 90660 | — |
| Alkermes Investigational Site | Redlands | California | 92374 | — |
| Alkermes Investigational Site | Santa Ana | California | 92705 | — |
| Alkermes Investigational Site | Sherman Oaks | California | 91403 | — |
| Alkermes Investigational Site | Temecula | California | 92591 | — |
| Alkermes Investigative Site | Upland | California | 91786 | — |
| Alkermes Investigational Site | Hollywood | Florida | 33024 | — |
| Alkermes Investigational Site | Jacksonville | Florida | 32256 | — |
| Alkermes Investigational Site | Lauderhill | Florida | 33319 | — |
| Alkermes Investigational Site | Orlando | Florida | 32801 | — |
| Alkermes Investigative Site | Palm Bay | Florida | 32905 | — |
| Alkermes Investigational Site | Atlanta | Georgia | 30341 | — |
| Alkermes Investigational Site | Decatur | Georgia | 30030 | — |
| Alkermes Investigational Site | Pikesville | Maryland | 21208 | — |
| Alkermes Investigational Site | O'Fallon | Missouri | 63368 | — |
| Alkermes Investigational Site | Jamaica | New York | 11432 | — |
| Alkermes Investigational Site | Mount Kisco | New York | 10549 | — |
| Alkermes Investigational Site | Canton | Ohio | 44720 | — |
| Alkermes Investigational Site | Cincinnati | Ohio | 45215 | — |
| Alkermes Investigational Site | Oklahoma City | Oklahoma | 73112 | — |
| Alkermes Investigational Site | Allentown | Pennsylvania | 18104 | — |
| Alkermes Investigational Site | Memphis | Tennessee | 38119 | — |
| Alkermes Investigational Site | Dallas | Texas | 75390 | — |
| Alkermes Investigational Site | DeSoto | Texas | 75115 | — |
| Alkermes Investigational Site | Woodstock | Vermont | 05091 | — |
| Alkermes Investigative Site | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03188185, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 8, 2021 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03188185 live on ClinicalTrials.gov.