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Terminated Phase 3 Interventional Results available

AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

ClinicalTrials.gov ID: NCT03192215

Public ClinicalTrials.gov record NCT03192215. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Objectives * Primary: To test the hypothesis that apixaban is superior to aspirin for the prevention of recurrent stroke in patients with cryptogenic ischemic stroke and atrial cardiopathy. * Secondary: To test the hypothesis that the relative efficacy of apixaban over aspirin increases with the severity of atrial cardiopathy.

Study identification

NCT ID
NCT03192215
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Columbia University
Other
Enrollment
1,015 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
45 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 19, 2018 (Actual)
Primary completion
Mar 31, 2023 (Actual)
Completion
Apr 17, 2023 (Actual)
Last update posted
Apr 9, 2025

2018 – 2023

United States locations

U.S. sites
165
U.S. states
41
U.S. cities
114
Facility City State ZIP Site status
University of Alabama Birmingham Alabama 35233 —
University of South Alabama University Hospital Mobile Alabama 36604 —
Chandler Regional Medical Center Chandler, AZ Chandler Arizona 85224 —
St. Joseph's Hospital and Medical Center Phoenix Arizona 85013 —
Banner University Medical Center - Tucson Tucson Arizona 85724 —
Mercy San Juan Medical Center (Dignity Health) Carmichael California 95608 —
Eden Medical Center Castro Valley California 94546 —
Rancho Los Amigos National Rehabilitation Center Downey California 90242 —
Fountain Valley Regional Hospital and Medical Center Fountain Valley California 92708 —
Community Regional Medical Center Fresno California 93721 —
UCSD Health La Jolla La Jolla California 92037 —
Sharp Grossmont Hospital La Mesa California 92123 —
Long Beach Memorial Medical Center Long Beach California 90806 —
Los Alamitos Medical Center Los Alamitos California 90720 —
Kaiser Permanente Los Angeles California 90027 —
Keck Hospital Of USC Los Angeles California 90033 —
Los Angeles County- USC Medical Center Los Angeles California 90033 —
VA Greater Los Angeles - West LA VA Medical Center Los Angeles California 90073 —
Ronald Reagan UCLA Medical Center Los Angeles California 90095 —
UC Irvine Medical Center Orange California 92868 —
Sutter Medical Center Sacramento California 95816 —
Salinas Valley Memorial Hospital Salinas California 93901 —
Scripps Mercy San Diego California 91910 —
UCSD Medical Center - Hillcrest Hospital San Diego California 92103 —
Kaiser Permanent San Diego Medical Center San Diego California 92123 —
Sharp Memorial Hospital San Diego California 92123 —
San Francisco General San Francisco California 94110 —
UCSF Medical Center San Francisco California 94143 —
Good Samaritan San Jose California 95124 —
Stanford University Medical Center Stanford California 94305 —
Swedish Medical Center Englewood Colorado 80113 —
St. Mary's Medical Center Grand Junction Colorado 81501 —
St. Vincent's Medical Center Bridgeport Connecticut 06606 —
Hartford Hospital Hartford Connecticut 06102-5037 —
Yale New Haven Hospital New Haven Connecticut 06520 —
Christiana Hospital Newark Delaware 19718 —
Med-star Georgetown Univ. Washington D.C. District of Columbia 20007 —
Medstar Washington Washington D.C. District of Columbia 20010 —
Boca Raton Regional Hospital Boca Raton Florida 33486 —
UF Health Shands Gainesville Florida 32610 —
Baptist Medical Center Jacksonville Jacksonville Florida 32207 —
Mayo Clinic Jacksonville Florida 32224 —
Jackson Memorial Miami Florida 33136 —
Univ. Miami Hospital Miami Florida 33136 —
Baptist Hospital of Miami Miami Florida 33176 —
Intercoastal Medical Group - Hyde Park Sarasota Florida 34239 —
Tampa General Tampa Florida 33606 —
Emory University Atlanta Georgia 30303 —
Grady Memorial Atlanta Georgia 30303 —
The Queen's Medical Center Honolulu Hawaii 96813 —
Northwestern Memorial Hospital Chicago Illinois 60611 —
Rush University Chicago Illinois 60612 —
University of Illinois Chicago Illinois 60612 —
University of Chicago Medical Center Chicago Illinois 60637 —
OSF St. Francis Medical Center Peoria Illinois 61637 —
Southern Illinois University Memorial Medical Center Springfield Illinois 62702 —
St. John's Hospital (Prairie Research) Springfield Illinois 62769 —
Central DuPage Hospital Winfield Illinois 60190 —
Multi-Specialty - Methodist Plaza/Unity Point Des Moines Iowa 50309 —
University of Iowa Iowa City Iowa 52242 —
University of Kansas Kansas City Kansas 66160 —
Baptist Health Lexington Lexington Kentucky 40503 —
University of Kentucky Lexington Kentucky 40536 —
University of Louisville Hospital Louisville Kentucky 40202 —
Ochsner Medical Center New Orleans Louisiana 70121 —
Eastern Maine Medical Center Bangor Maine 04401 —
University of Maryland Medical Center Baltimore Maryland 21201 —
Tufts Medical Center Boston Massachusetts 02111 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Boston Medical Center Boston Massachusetts 02118 —
Beth Israel Deaconess Medical Boston Massachusetts 02215 —
Brigham & Womens Hospital Boston Massachusetts 20115 —
Lahey Hospital & Medical Center Burlington Massachusetts 01805 —
U Mass Memorial Medical Center Worcester Massachusetts 01655 —
University of Michigan University Hospital Ann Arbor Michigan 48109 —
VA Ann Arbor Healthcare System Ann Arbor Michigan 48109 —
Detroit Receiving Hospital Detroit Michigan 48201 —
Henry Ford Hospital Detroit Michigan 48202 —
McLaren Flint Flint Michigan 48532 —
Mercy Health St. Mary's Grand Rapids Michigan 49503 —
Spectrum Health Grand Rapids Michigan 49503 —
McLaren Macomb, Mount Clemens, MI Mount Clemens Michigan 48043 —
McLaren Northern Michigan Petoskey Michigan 49770 —
Abbott Northwestern Hospital Minneapolis Minnesota 55407 —
Hennepin County Minneapolis Minnesota 55415 —
Univ. of Minnesota Minneapolis Minnesota 55455 —
Mayo Clinic Rochester Minnesota 55905 —
Regions Hospital, St. Paul Saint Paul Minnesota 55101 —
United Hospital Saint Paul Minnesota 55102 —
University of Mississippi Medical Center Jackson Mississippi 39216 —
Saint Luke's Hospital of Kansas City Kansas City Missouri 64111 —
Cox Medical Center South Springfield Missouri 65807 —
St. Louis University Hospital St Louis Missouri 63104 —
Barnes Jewish Hospital St Louis Missouri 63110 —
CHI Health Immanuel Omaha Nebraska 68124 —
University of Nebraska Omaha Nebraska 68198 —
Cooper University Hospital, Camden New Jersey 08103 —
Robert Wood Johnson New Brunswick New Jersey 08901 —
Capital Health Medical Center Hopewell Pennington New Jersey 08534 —
Univ. New Mexico Albuquerque New Mexico 87131 —
Kings County Hospital Brooklyn New York 11203 —
New York Presbyterian - Brooklyn Methodist Hospital Brooklyn New York 11215-3609 —
Maimonides Medical Center Brooklyn New York 11219 —
NYU Langone Hospital - Brooklyn Brooklyn New York 11220 —
Mount Sinai Beth Israel Brooklyn Brooklyn New York 11234 —
Buffalo General Medical Center Buffalo New York 14203 —
North Shore University Hospital Manhasset New York 11042 —
NYU Langone New York New York 10003 —
Mount Sinai West New York New York 10019 —
Columbia University Medical Center New York New York 10032 —
Weill Cornell Medicine New York New York 10065 —
Lenox Hill Hospital New York New York 10075 —
Strong Memorial Hospital Rochester New York 14642 —
Montefiore Medical Center The Bronx New York 10467 —
Moses H. Cone Memorial Hospital Greensboro North Carolina 27405 —
Wake Forest Baptist Medical Center Winston-Salem North Carolina 27157 —
Sanford Medical Center Fargo Fargo North Dakota 58122 —
Akron General Medical Center Akron Ohio 44307 —
University of Cincinnati Cincinnati Ohio 45219 —
Louis Stokes VA Medical Center Cleveland Ohio 44106 —
UH Cleveland Medical Center Cleveland Ohio 44106 —
MetroHealth Medical Center Cleveland Ohio 44109 —
Cleveland Clinic Cleveland Ohio 44195 —
OSU Wexner Columbus Ohio 43210 —
Ohio Health Riverside - Riverside Methodist Hospital Columbus Ohio 43214 —
Miami Valley Hospita Dayton Ohio 45409 —
Mercy St Vincent Medical Center Toledo Ohio 43608 —
OU Medical Center Oklahoma Oklahoma City Oklahoma 73104 —
Legacy Emanuel Portland Oregon 97227 —
Oregon Health and Sciences Portland Oregon 97239 —
Lehigh Valley Hospital Allentown Pennsylvania 18103 —
UPMC Altoona Altoona Pennsylvania 16601 —
Lancaster General Hospital Lancaster Pennsylvania 17602 —
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104 —
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107 —
Temple University Philadelphia Pennsylvania 19140 —
Allegheny General Hospital Pittsburgh Pennsylvania 15212 —
UPMC Presbyterian Pittsburgh Pennsylvania 15213 —
Rhode Island Hospital Providence Rhode Island 02903 —
Medical University of South Carolina Charleston South Carolina 29425 —
Prisma Health Richland Hospital (formerly Palmetto Health) Columbia South Carolina 29203 —
Prisma Health Greenville Memorial Hospital Greenville South Carolina 29605 —
Methodist University Hospital Memphis Tennessee 38104 —
Vanderbilt Nashville Tennessee 37212 —
UT Southwestern Medical Center Dallas Texas 75390 —
Valley Bapist Harlingen Texas 78550 —
Baylor College College of Medicine Houston Texas 77030 —
Houston Methodist Hospital Houston Texas 77030 —
Memorial Hermann Texas Medical Center Houston Texas 77030 —
Univ of Texas Health Science Center San Antonio San Antonio Texas 78229 —
Scott & White Memorial Hospital - Temple Temple Texas 76508 —
Memorial Hermann The Woodlands Hospital The Woodlands Texas 77380 —
Intermountain Medical Center Murray Utah 84107 —
Utah Valley Regional Medical Center Provo Utah 84604 —
Univ of Utah Salt Lake City Utah 84132 —
George E Whalen VA Salt Lake City Utah 84148 —
UVA Medical Center Charlottesville Virginia 22908 —
Bon Secours St. Mary's Hospital Richmond Virginia 23226 —
Providence St. Peter Hospital Olympia Washington 98506 —
Harborview Medical Center Seattle Washington 98104 —
Puget Sound VA Seattle Washington 98108 —
Swedish Medical Center - Cherry Hill Campus Seattle Washington 98122 —
WVU Healthcare Ruby Memorial Morgantown West Virginia 26506-9180 —
University of Wisconsin Madison Wisconsin 53792 —
Froedtert Hospital Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03192215, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 9, 2025 · Synced Oct 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03192215 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →