ClinicalTrials.gov record
Retrospective Chart Review of First-time Opsumit® (Macitentan) Users in the United States
ClinicalTrials.gov ID: NCT03197688
Public ClinicalTrials.gov record NCT03197688. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Retrospective Chart Review of First-time Opsumit® (Macitentan) Users in the United States
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Opsumit Users registry (OPUS; NCT02126943) was developed to characterize the safety profile of Opsumit and to describe clinical characteristics and outcomes of patients newly treated with Opsumit in the post-marketing setting. It is expected that the recruitment target of the OPUS registry cannot be achieved within the planned time period (5000 Opsumit new users by October 2018). The OrPHeUS study is designed to supplement the OPUS registry with retrospectively identified first-time Opsumit users in order to achieve the desired sample size.
Study identification
- NCT ID
- NCT03197688
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 2,200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 3, 2017 (Actual)
- Primary completion
- Sep 6, 2018 (Actual)
- Completion
- Sep 6, 2018 (Actual)
- Last update posted
- Mar 30, 2025
2017 – 2018
United States locations
- U.S. sites
- 105
- U.S. states
- 35
- U.S. cities
- 92
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pulmonary Associates | Phoenix | Arizona | 85006 | — |
| Cardiovascular Consultants | Phoenix | Arizona | 85032 | — |
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | — |
| University of California San Diego | La Jolla | California | 93093 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| David Geffen School of Medicine at University of California Los Angeles | Los Angeles | California | 90095-1690 | — |
| UCSF School of Medicine | San Francisco | California | 94143 | — |
| Paloma Medical Group | San Juan Capistrano | California | 92675 | — |
| Santa Barbara Cottage Hospital | Santa Barbara | California | 93105 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Christiana Care Health Services | Newark | Delaware | 19718 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Bay Area Cardiology Associates | Brandon | Florida | 33511 | — |
| Florida Lung, Asthma and Sleep Specialists | Celebration | Florida | 34747 | — |
| Frank Hull, MD, PA | Fort Lauderdale | Florida | 33316 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| West Pasco Pulmonary Associates | Hudson | Florida | 34667 | — |
| Saint Vincent's Medical Center | Jacksonville | Florida | 32209 | — |
| Medical Research of Central Florida | Leesburg | Florida | 34748 | — |
| Independent Lung Associates | Melbourne | Florida | 32901 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| Central Florida Pulmonary Group, P.A. - Downtown Orlando Office | Orlando | Florida | 32803 | — |
| Bassetti Medical Research Inc | Sebring | Florida | 33870 | — |
| Cardiovascular Medicine Associates | South Miami | Florida | 33143 | — |
| Coastal Pulmonary and Critical Care | St. Petersburg | Florida | 33704 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Cleveland Clinic Florida Hospital | Weston | Florida | 33331 | — |
| Florida Medical Clinic | Zephyrhills | Florida | 33542 | — |
| Piedmont Healthcare | Austell | Georgia | 30106 | — |
| Southeastern Cardiology Associates | Columbus | Georgia | 31904 | — |
| Wellstar Marietta Pulmonary Medicine | Marietta | Georgia | 30060 | — |
| Bingham Memorial Hospital | Shelley | Idaho | 83274 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| IU Health Physicians Pulmonary & Critical Care | Carmel | Indiana | 46032 | — |
| Lutheran Hospital | Fort Wayne | Indiana | 46804 | — |
| Indiana Internal Medicine Consultants | Greenwood | Indiana | 46143 | — |
| St. Vincent Medical Group, Inc. | Indianapolis | Indiana | 46260 | — |
| CIC Associates | Clive | Iowa | 50325 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| The University of Kansas Physicians | Kansas City | Kansas | 66160 | — |
| St. Elizabeth Healthcare Clinical Research Institute | Erlanger | Kentucky | 41018 | — |
| Kentuckiana Pulmonary Associates | Louisville | Kentucky | 40202 | — |
| LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Pulmonary & Critical Care Specialists | Shreveport | Louisiana | 71105 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Sparrow Clinical Research Institute | Lansing | Michigan | 48912 | — |
| Beaumont Medical Center | Troy | Michigan | 48085 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407-3799 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Pulmonary Consultants Inc-St. Louis | St Louis | Missouri | 63136 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Nebraska Pulmonary Specialties, LLC | Lincoln | Nebraska | 68506 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-5990 | — |
| Barnabas Health Ambulatory Care Center | Newark | New Jersey | 07112 | — |
| Pulmonary and Critical Care Associates | Union | New Jersey | 07083 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131-0001 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| Pulmonary Health Physicians | Fayetteville | New York | 13066 | — |
| Stony Brook University Hospital | Hauppauge | New York | 11788 | — |
| Temple University Hospital | Middletown | New York | 10941 | — |
| Winthrop University Hospital, Clinical Trials Center | Mineola | New York | 11501 | — |
| Mount Sinai | New York | New York | 10029 | — |
| Montefiore Medical Center - Bronx | The Bronx | New York | 10467 | — |
| University of North Carolina Hospitals | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| University of Cincinnati | Cincinnati | Ohio | 45242 | — |
| Ohio State University, Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Mount Carmel Medical Group | Columbus | Ohio | 43213 | — |
| Midwest Pulmonary & Sleep Research | Dayton | Ohio | 45459 | — |
| Southwest General Health Center | Middleburg Heights | Ohio | 44130 | — |
| The University of Toledo Medical Center | Toledo | Ohio | 43614 | — |
| Oklahoma Heart Hospital | Oklahoma City | Oklahoma | 73120 | — |
| Oregon Health & Science University | Portland | Oregon | 97201-3098 | — |
| Legacy Research Institute | Portland | Oregon | 97210 | — |
| The Oregon Clinic | Portland | Oregon | 97225 | — |
| Doylestown Health Cardiology, a division of Doylestown Health Physicians | Doylestown | Pennsylvania | 18907 | — |
| University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| AnMed Health Medical Center | Anderson | South Carolina | 29621 | — |
| Carolina Cardiology Associates | Rock Hill | South Carolina | 29732 | — |
| Sioux Falls Cardiovascular PC | Sioux Falls | South Dakota | 57108 | — |
| Memorial Research Center | Chattanooga | Tennessee | 37404 | — |
| Mid-South Pulmonary Specialists | Memphis | Tennessee | 38157 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390-8550 | — |
| Premier Pulmonary CC and Sleep Medicine, PA | Denison | Texas | 75020 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Baylor Regional Medical Center at Plano | Plano | Texas | 75093 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508-0001 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| Spokane Respiratory Consultants | Spokane | Washington | 99204-4800 | — |
| Cardiac Study Center | Tacoma | Washington | 98405 | — |
| Aurora Health Care - Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03197688, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2025 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03197688 live on ClinicalTrials.gov.