Nilotinib in Parkinson's Disease
Public ClinicalTrials.gov record NCT03205488. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Phase IIa, Parallel Group, Two Cohort Study to Define the Safety, Tolerability, Clinical and Exploratory Biological Activity of the Chronic Administration of Nilotinib in Participants With Parkinson's Disease
Study identification
- NCT ID
- NCT03205488
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Northwestern University
- Other
- Enrollment
- 76 participants
Conditions and interventions
Conditions
Interventions
- Cohort 1:Nilotinib Oral Capsules (150mg or 300mg) Drug
- Cohort 2: Nilotinib Oral Capsules (dose to be determined from Cohort 1) Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years to 79 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 15, 2017
- Primary completion
- Aug 25, 2019
- Completion
- Sep 27, 2019
- Last update posted
- Jul 21, 2020
2017 – 2019
United States locations
- U.S. sites
- 24
- U.S. states
- 20
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294-0017 | — |
| Barrow Neurological Institute | Sun City | Arizona | 85013 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| University of Colorado at Denver | Aurora | Colorado | 80045 | — |
| University of Florida | Gainesville | Florida | 32607 | — |
| University of South Florida | Tampa | Florida | 33620 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| John Hopkins University | Baltimore | Maryland | 21093 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Cleveland Clinic - Las Vegas | Las Vegas | Nevada | 89106 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19107 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
| Inland Northwest Research | Spokane | Washington | 99202 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03205488, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2020 · Synced May 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03205488 live on ClinicalTrials.gov.