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Completed Phase 1Phase 2 Interventional Results available

Brentuximab Vedotin for Systemic Sclerosis

ClinicalTrials.gov ID: NCT03222492

Public ClinicalTrials.gov record NCT03222492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 9:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of Brentuximab Vedotin for Diffuse Cutaneous Systemic Sclerosis BRAVOS: A Phase 1/2 Multicenter Randomized, Double Blinded, Safety Study (ITN075AI)

Study identification

NCT ID
NCT03222492
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
17 participants

Conditions and interventions

Interventions

  • Brentuximab Vedotin Biological
  • Placebo Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 19, 2017
Primary completion
Apr 9, 2023
Completion
Apr 9, 2023
Last update posted
May 4, 2026

2017 – 2023

United States locations

U.S. sites
8
U.S. states
8
U.S. cities
8
Facility City State ZIP Site status
UCLA Medical Center: Division of Rheumatology Los Angeles California 90095
Georgetown University Medical Center: Division of Rheumatology Washington D.C. District of Columbia 20057
University of Michigan Health System: Department of Internal Medicine, Division of Rheumatology Ann Arbor Michigan 48109
Hospital for Special Surgery, New York: Division of Rheumatology New York New York 10021
Duke University Medical Center: Division of Rheumatology and Immunology Durham North Carolina 27710
University of Pittsburgh Medical Center: Division of Rheumatology and Clinical Pittsburgh Pennsylvania 15217
Medical University of South Carolina: Division of Rheumatology & Immunology Charleston South Carolina 29425
University of Texas Houston Medical School: Division of Rheumatology and Clinical Immunogenetics Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03222492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2026 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03222492 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →