ClinicalTrials.gov record
Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma
ClinicalTrials.gov ID: NCT03224767
Public ClinicalTrials.gov record NCT03224767. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 8:09 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II Trial of BRAF/MEK Inhibitors in Papillary Craniopharyngiomas
Study identification
- NCT ID
- NCT03224767
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Alliance for Clinical Trials in Oncology
- Other
- Enrollment
- 24 participants
Conditions and interventions
Interventions
- Cobimetinib Drug
- Laboratory Biomarker Analysis Other
- Quality-of-Life Assessment Other
- Vemurafenib Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 4, 2018
- Primary completion
- Sep 30, 2026
- Completion
- Jul 31, 2028
- Last update posted
- Feb 17, 2025
2018 – 2028
United States locations
- U.S. sites
- 106
- U.S. states
- 25
- U.S. cities
- 88
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California | 95603 | — |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | 94704 | — |
| Mills-Peninsula Medical Center | Burlingame | California | 94010 | — |
| Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California | 95682 | — |
| Eden Hospital Medical Center | Castro Valley | California | 94546 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Memorial Medical Center | Modesto | California | 95355 | — |
| Palo Alto Medical Foundation-Camino Division | Mountain View | California | 94040 | — |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| Palo Alto Medical Foundation Health Care | Palo Alto | California | 94301 | — |
| Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | 95661 | — |
| Sutter Roseville Medical Center | Roseville | California | 95661 | — |
| Sutter Medical Center Sacramento | Sacramento | California | 95816 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | — |
| Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | 94086 | — |
| Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville | California | 95687 | — |
| Sutter Solano Medical Center/Cancer Center | Vallejo | California | 94589 | — |
| Smilow Cancer Center/Yale-New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Smilow Cancer Hospital Care Center-Trumbull | Trumbull | Connecticut | 06611 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224-9980 | — |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | — |
| Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | 83605 | — |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | — |
| Idaho Urologic Institute-Meridian | Meridian | Idaho | 83642 | — |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | — |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Central Care Cancer Center - Garden City | Garden City | Kansas | 67846 | — |
| Central Care Cancer Center - Great Bend | Great Bend | Kansas | 67530 | — |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | — |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Grand Rapids | Michigan | 49503 | — |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| Trinity Health Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49048 | — |
| Trinity Health Muskegon Hospital | Muskegon | Michigan | 49444 | — |
| Corewell Health Lakeland Hospitals - Niles Hospital | Niles | Michigan | 49120 | — |
| Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | 49444 | — |
| Corewell Health Reed City Hospital | Reed City | Michigan | 49677 | — |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital | Saint Joseph | Michigan | 49085 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| University of Michigan Health - West | Wyoming | Michigan | 49519 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Minnesota Oncology - Burnsville | Burnsville | Minnesota | 55337 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | 55369 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | — |
| Monticello Cancer Center | Monticello | Minnesota | 55362 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Central Care Cancer Center - Bolivar | Bolivar | Missouri | 65613 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Community Medical Center | Missoula | Montana | 59804 | — |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | — |
| Rutgers New Jersey Medical School | Newark | New Jersey | 07101 | — |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| NYP/Weill Cornell Medical Center | New York | New York | 10065 | — |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Cancer Centers of Southwest Oklahoma Research | Lawton | Oklahoma | 73505 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| Farmington Health Center | Farmington | Utah | 84025 | — |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | — |
| South Jordan Health Center | South Jordan | Utah | 84009 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
| FHCC South Lake Union | Seattle | Washington | 98109 | — |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | — |
| University of Washington Medical Center - Montlake | Seattle | Washington | 98195 | — |
| United Hospital Center | Bridgeport | West Virginia | 26330 | — |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | — |
| Camden Clark Medical Center | Parkersburg | West Virginia | 26101 | — |
| Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03224767, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 17, 2025 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03224767 live on ClinicalTrials.gov.