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Terminated Phase 1Phase 2 Interventional Results available

Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease

ClinicalTrials.gov ID: NCT03225846

Public ClinicalTrials.gov record NCT03225846. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 10:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 1b/2a Study of WVE-120102 Administered Intrathecally in Patients With Huntington's Disease

Study identification

NCT ID
NCT03225846
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Wave Life Sciences USA, Inc.
Industry
Enrollment
88 participants

Conditions and interventions

Interventions

  • WVE-120102 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
25 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 16, 2017
Primary completion
May 9, 2021
Completion
May 9, 2021
Last update posted
Apr 24, 2022

2017 – 2021

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
University of California San Diego La Jolla California 92037-0949
University of California Davis Medical Center Sacramento California 95817
Massachusetts General Hospital Boston Massachusetts 02129
The Ohio State University Columbus Ohio 43210
Vanderbilt University Medical Center Nashville Tennessee 37232

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03225846, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 24, 2022 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03225846 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →