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Completed Phase 1 Interventional Accepts healthy volunteers Results available

Evaluating the Infectivity, Safety, and Immunogenicity of Recombinant Live-Attenuated RSV Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 in RSV-Seronegative Infants 6 to 24 Months of Age

ClinicalTrials.gov ID: NCT03227029

Public ClinicalTrials.gov record NCT03227029. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized Phase I Study of the Infectivity, Safety, and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Infants 6 to 24 Months of Age

Study identification

NCT ID
NCT03227029
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
65 participants

Conditions and interventions

Interventions

  • Placebo Biological
  • RSV 276 Biological
  • RSV ΔNS2/Δ1313/I1314L Biological

Biological

Eligibility (public fields only)

Age range
6 Months to 24 Months
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 21, 2017
Primary completion
Dec 18, 2019
Completion
Sep 30, 2020
Last update posted
Apr 21, 2022

2017 – 2020

United States locations

U.S. sites
12
U.S. states
8
U.S. cities
10
Facility City State ZIP Site status
University of California, UC San Diego CRS- Mother-Child-Adolescent HIV Program La Jolla California 92093-0672
Usc La Nichd Crs Los Angeles California 90089
David Geffen School of Medicine at UCLA NICHD CRS Los Angeles California 90095-1752
Univ. of Colorado Denver NICHD CRS Aurora Colorado 80045
Rush Univ. Cook County Hosp. Chicago NICHD CRS Chicago Illinois 60612
Lurie Children's Hospital of Chicago (LCH) CRS Chicago Illinois 60614-3393
Johns Hopkins University Center for Immunization Research Baltimore Maryland 21205
Boston Medical Center Ped. HIV Program NICHD CRS Boston Massachusetts 02118
SUNY Stony Brook NICHD CRS Stony Brook New York 11794
Jacobi Med. Ctr. Bronx NICHD CRS The Bronx New York 10461
St. Jude Children's Research Hospital CRS Memphis Tennessee 38105-3678
Texas Children's Hospital CRS Houston Texas 77030-2399

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03227029, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 21, 2022 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03227029 live on ClinicalTrials.gov.

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