ClinicalTrials.gov record
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
ClinicalTrials.gov ID: NCT03233191
Public ClinicalTrials.gov record NCT03233191. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.
Study identification
- NCT ID
- NCT03233191
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 108,508 participants
Conditions and interventions
Conditions
Interventions
- Digital Mammography Procedure
- Digital Tomosynthesis Mammography Procedure
- Laboratory Biomarker Analysis Other
Procedure · Other
Eligibility (public fields only)
- Age range
- 45 Years to 74 Years
- Sex
- Female
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 28, 2017 (Actual)
- Primary completion
- Mar 31, 2028 (Estimated)
- Completion
- Dec 31, 2029 (Estimated)
- Last update posted
- Sep 4, 2026
2017 – 2029
United States locations
- U.S. sites
- 133
- U.S. states
- 36
- U.S. cities
- 110
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Mobile Infirmary Medical Center | Mobile | Alabama | 36607 | — |
| Banner-University Medical Center Phoenix | Phoenix | Arizona | 85006 | — |
| University of Arizona College of Medicine Phoenix | Phoenix | Arizona | 85006 | — |
| Valleywise Comprehensive Health Center - Phoenix | Phoenix | Arizona | 85008 | — |
| Mayo Clinic Hospital in Arizona | Phoenix | Arizona | 85054 | — |
| Scottsdale Medical Imaging Limited | Scottsdale | Arizona | 85258 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Kern Radiology Medical Group Inc | Bakersfield | California | 93306 | — |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Kaiser Permanente-Modesto | Modesto | California | 95356 | — |
| Zuckerberg San Francisco General Hospital | San Francisco | California | 94110 | — |
| UCHealth University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| The Women's Imaging Center | Denver | Colorado | 80209 | — |
| Radiology Imaging Associates | Englewood | Colorado | 80112 | — |
| UCHealth Highlands Ranch Hospital | Highlands Ranch | Colorado | 80129 | — |
| UCHealth Lone Tree Health Center | Lone Tree | Colorado | 80124 | — |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| University of Florida Health Science Center - Jacksonville | Jacksonville | Florida | 32209 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Northeast Georgia Medical Center Braselton | Braselton | Georgia | 30517 | — |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | 31405 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | — |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | — |
| Bromenn Lifecare Center | Bloomington | Illinois | 61701 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Carle at The Riverfront | Danville | Illinois | 61832 | — |
| Carle on Fairchild | Danville | Illinois | 61832 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Carle Hoopeston Regional Health Center | Hoopeston | Illinois | 60942 | — |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | — |
| Bromenn Regional Medical Center | Normal | Illinois | 61761 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Saint Mary Medical Center | Hobart | Indiana | 46342 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| The Community Hospital | Munster | Indiana | 46321 | — |
| Women's Diagnostic Center - Munster | Munster | Indiana | 46321 | — |
| Northwest Cancer Center - Valparaiso | Valparaiso | Indiana | 46383 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| Owensboro Health Mitchell Memorial Cancer Center | Owensboro | Kentucky | 42303 | — |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | — |
| Woman's Hospital | Baton Rouge | Louisiana | 70817 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| University Medical Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Ochsner LSU Health Saint Mary's Medical Center | Shreveport | Louisiana | 71101 | — |
| LSU Health Sciences Center at Shreveport | Shreveport | Louisiana | 71103 | — |
| Kaiser Permanente - Kensington Medical Center | Kensington | Maryland | 20895 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| UMass Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | — |
| Trinity Health Saint Joseph Mercy Hospital Ann Arbor | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | — |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Grand Rapids | Michigan | 49503 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | 48322 | — |
| Essentia Health Cancer Center | Duluth | Minnesota | 55805 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Sanford Thief River Falls Medical Center | Thief River Falls | Minnesota | 56701 | — |
| Essentia Health Virginia Clinic | Virginia | Minnesota | 55792 | — |
| Baptist Memorial Hospital and Cancer Center-Desoto | Southhaven | Mississippi | 38671 | — |
| Carson Tahoe Regional Medical Center | Carson City | Nevada | 89703 | — |
| Hunterdon Medical Center | Flemington | New Jersey | 08822 | — |
| Saint Peter's University Hospital | New Brunswick | New Jersey | 08901 | — |
| Riverview Medical Center/Booker Cancer Center | Red Bank | New Jersey | 07701 | — |
| Sidney Kimmel Cancer Center Washington Township | Sewell | New Jersey | 08080 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| Arnot Ogden Medical Center/Falck Cancer Center | Elmira | New York | 14905 | — |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| NYP/Weill Cornell Medical Center | New York | New York | 10065 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | — |
| Montefiore Medical Center-Weiler Hospital | The Bronx | New York | 10461 | — |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| University of North Carolina-Hillsborough Campus | Hillsborough | North Carolina | 27278 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Southpointe-Sanford Medical Center Fargo | Fargo | North Dakota | 58103 | — |
| Cleveland Clinic Cancer Center Beachwood | Beachwood | Ohio | 44122 | — |
| Aultman Health Foundation | Canton | Ohio | 44710 | — |
| University of Cincinnati Cancer Center-UC Medical Center | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Easton Hospital | Easton | Pennsylvania | 18042 | — |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Wexford Health and Wellness Pavilion | Wexford | Pennsylvania | 15090 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Prisma Health Richland Hospital | Columbia | South Carolina | 29203 | — |
| Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | 29605 | — |
| MUSC Health East Cooper | Mt. Pleasant | South Carolina | 29464 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| Spartanburg Medical Center - Mary Black Campus | Spartanburg | South Carolina | 29307 | — |
| University of Tennessee - Knoxville | Knoxville | Tennessee | 37920 | — |
| Baptist Memorial Hospital and Cancer Center-Memphis | Memphis | Tennessee | 38120 | — |
| Baptist Memorial Hospital for Women | Memphis | Tennessee | 38120 | — |
| Vanderbilt Breast Center at One Hundred Oaks | Nashville | Tennessee | 37204 | — |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| Memorial Hermann Texas Medical Center | Houston | Texas | 77030 | — |
| Memorial Hermann Imaging Center - Upper Kirby | Houston | Texas | 77098 | — |
| University Hospital | San Antonio | Texas | 78229 | — |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | — |
| Bon Secours Westchester Emergency Center | Midlothian | Virginia | 23113 | — |
| Sentara Leigh Hospital | Norfolk | Virginia | 23502 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Sentara Princess Anne Hospital | Virginia Beach | Virginia | 23456 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | — |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | — |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54911 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | — |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | — |
| ProHealth D N Greenwald Center | Mukwonago | Wisconsin | 53149 | — |
| ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | 53066 | — |
| Essentia Health Saint Mary's Hospital - Superior | Superior | Wisconsin | 54880 | — |
| UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03233191, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 4, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03233191 live on ClinicalTrials.gov.