A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1)
Public ClinicalTrials.gov record NCT03248492. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Open-Label Study of DS-8201a, an Anti-HER2-Antibody Drug Conjugate (ADC) for HER2-Positive, Unresectable and/or Metastatic Breast Cancer Subjects Previously Treated With T-DM1 (DESTINY-Breast01)
Study identification
- NCT ID
- NCT03248492
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Daiichi Sankyo
- Industry
- Enrollment
- 253 participants
Conditions and interventions
Conditions
Interventions
- DS-8201a Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 24, 2017
- Primary completion
- Mar 20, 2019
- Completion
- May 5, 2024
- Last update posted
- Jun 25, 2025
2017 – 2024
United States locations
- U.S. sites
- 36
- U.S. states
- 18
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Urological Institute dba Alaska Clinical Research Center | Anchorage | Alaska | 99508 | — |
| Arizona Oncology Associates | Tucson | Arizona | 85704 | — |
| The Regents of the University of California | Los Angeles | California | 90095 | — |
| Sharp Clinical Oncology Research | San Diego | California | 92123 | — |
| University of California San Francisco | San Francisco | California | 94115 | — |
| Sansum Clinic | Santa Barbara | California | 93105 | — |
| Innovative Clinical Research Institute, LLC | Whittier | California | 90603 | — |
| Sylvester Comprehensive Cancer Center - Deerfield Beach | Boca Raton | Florida | 33426 | — |
| Specialist Global Research | Hialeah | Florida | 33012 | — |
| Miami Cancer Institute at Baptist Health, Inc. | Miami | Florida | 33176 | — |
| Piedmont Cancer Institute | Atlanta | Georgia | 30318 | — |
| Straub Medical Center | Honolulu | Hawaii | 96813 | — |
| University of Hawaii | Honolulu | Hawaii | 96813 | — |
| Norton Healthcare | Louisville | Kentucky | 40202 | — |
| University of Louisville Research Foundation | Louisville | Kentucky | 40202 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70120 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| North Shore Hematology Oncology Associates PC DBA NY Cancer and Blood Specialists | East Setauket | New York | 11733 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Aultman Hospital Cancer Center | Canton | Ohio | 44710 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| St Francis Hospital | Greenville | South Carolina | 29601 | — |
| Accurate Clinical Research | Baytown | Texas | 77521 | — |
| Texas Oncology, P.A. | Dallas | Texas | 75246 | — |
| Texas Oncology - Memorial City | Houston | Texas | 77024 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| The Methodist Hospital Research Institute | Houston | Texas | 77030 | — |
| Texas Oncology, P.A. - Longview | Tyler | Texas | 75702 | — |
| The University of Texas Health Science Center at Tyler | Tyler | Texas | 75708 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Providence Regional Medical Center - Everett | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03248492, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2025 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03248492 live on ClinicalTrials.gov.