Phase 2a, Dose-ranging Study With PF-05221304 in Nonalcoholic Fatty Liver Disease (NAFLD)
Public ClinicalTrials.gov record NCT03248882. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2A, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING, PARALLEL GROUP STUDY TO EVALUATE SAFETY, TOLERABILITY, AND PHARMACODYNAMICS OF PF-05221304 ADMINISTERED DAILY FOR 16-WEEKS TO ADULT SUBJECTS WITH NONALCOHOLIC FATTY LIVER DISEASE
Study identification
- NCT ID
- NCT03248882
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 305 participants
Conditions and interventions
Interventions
- PF-05221304 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 21, 2017
- Primary completion
- Feb 25, 2019
- Completion
- Mar 26, 2019
- Last update posted
- Dec 8, 2020
2017 – 2019
United States locations
- U.S. sites
- 60
- U.S. states
- 19
- U.S. cities
- 46
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Franco Felizarta MD | Bakersfield | California | 93301 | — |
| eStudySite | Chula Vista | California | 91911 | — |
| San Diego Imaging Chula Vista | Chula Vista | California | 91911 | — |
| University of California, San Diego (Altman Clinical and Translational Research Institute) | La Jolla | California | 92037 | — |
| University of California, San Diego | La Jolla | California | 92037 | — |
| eStudySite | La Mesa | California | 91942 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| National Research Institute | Los Angeles | California | 90057 | — |
| Stanford University Medical Center, Blake wilbur Building | Palo Alto | California | 04304 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| Huntington Medical Research Institute | Pasadena | California | 91105 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| Precision Research Institute | San Diego | California | 92114 | — |
| Quest Clinical Research | San Francisco | California | 94115 | — |
| South Denver Gastroenterology, P.C. | Englewood | Colorado | 80113 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Borland-Groover Clinic | Jacksonville | Florida | 32256 | — |
| Schiff Center for Liver Diseases/University of Miami | Miami | Florida | 33136 | — |
| Stand Up MRI of Miami | Miami | Florida | 33145 | — |
| Ocean Blue Medical Research Center, Inc | Miami Springs | Florida | 33166 | — |
| Avail Clinical Research, LLC | Orange City | Florida | 32763 | — |
| Bioclinica Research | Orlando | Florida | 32806 | — |
| Advanced Gastroenterology Associates, LLC | Palm Harbor | Florida | 34684 | — |
| Qps-Mra, Llc | South Miami | Florida | 33143 | — |
| Tampa General Medical Group | Tampa | Florida | 33606 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| South Florida Center Of Gastroenterology, PA | Wellington | Florida | 33414 | — |
| Independent Imaging | Wellington | Florida | 33449 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Invision Imaging | Honolulu | Hawaii | 96814 | — |
| Midwest Institute for Clinical Research | Indianapolis | Indiana | 46260 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67207 | — |
| Ascension Via Christi Imaging at St. Francis | Wichita | Kansas | 67214 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Digestive Disease Associates, PA | Catonsville | Maryland | 21228 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Mayo Clinic- Main Campus | Rochester | Minnesota | 55905 | — |
| Gastrointestinal Associates, PA | Flowood | Mississippi | 39232 | — |
| Colonnades at Baptist | Jackson | Mississippi | 39202 | — |
| BioTelemetry Research | Rochester | New York | 14623 | — |
| Investigational Drug Service, University of North Carolina Hospitals | Chapel Hill | North Carolina | 27514 | — |
| The University of NC at Chapel Hill, Clinical and Translational Research Center (CTRC) | Chapel Hill | North Carolina | 27599 | — |
| The University of North Carolina at Chapel Hill, Biomedical Research Imaging Center (MRI Facility) | Chapel Hill | North Carolina | 27599 | — |
| Wake Research Associates, LLC | Raleigh | North Carolina | 27612 | — |
| PMG Research of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| PMG Research, Inc. | Winston-Salem | North Carolina | 27103 | — |
| Sterling Research Group, Ltd. | Cincinnati | Ohio | 45219 | — |
| Prime Imaging (Chattanooga Outpatient Center) | Chattanooga | Tennessee | 37404 | — |
| ClinSearch | Chattanooga | Tennessee | 37421 | — |
| Touchstone | Austin | Texas | 78705 | — |
| Baylor College of Medicine - Advanced Liver Therapies | Houston | Texas | 77030 | — |
| Pinnacle Clinical Research | Rollingwood | Texas | 78746 | — |
| Clinical Trials of Texas, Inc. | San Antonio | Texas | 78229 | — |
| Pinnacle Clinical Research, PLLC | San Antonio | Texas | 78229 | — |
| Clinical Research Advantage, Inc./Wasatch Peak Family Practice | Layton | Utah | 84041 | — |
| National Clinical Research - Richmond, Inc. | Richmond | Virginia | 23294 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03248882, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 8, 2020 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03248882 live on ClinicalTrials.gov.