Extracorporeal CO2 Removal With the Hemolung RAS for Mechanical Ventilation Avoidance During Acute Exacerbation of COPD
Public ClinicalTrials.gov record NCT03255057. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Multi-Center, Randomized, Controlled, Pivotal Trial to Validate the Safety and Efficacy of the Hemolung® Respiratory Assist System for COPD Patients Experiencing an Acute Exacerbation Requiring Ventilatory Support
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study evaluates the safety and efficacy of using the Hemolung RAS to provide low-flow extracorporeal carbon dioxide removal (ECCO2R) as an alternative or adjunct to invasive mechanical ventilation for patients who require respiratory support due to an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD). It is hypothesized that the Hemolung RAS can be safely used to avoid or reduce time on invasive mechanical ventilation compared to COPD patients treated with standard-of-care mechanical ventilation alone. Eligible patients will be randomized to receive lung support with either the Hemolung RAS plus standard-of-care mechanical ventilation, or standard-of-care mechanical ventilation alone.
Study identification
- NCT ID
- NCT03255057
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 113 participants
Conditions and interventions
Conditions
Interventions
Device
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 18, 2018 (Actual)
- Primary completion
- Aug 10, 2022 (Actual)
- Completion
- Aug 17, 2022 (Actual)
- Last update posted
- Oct 14, 2022
2018 – 2022
United States locations
- U.S. sites
- 32
- U.S. states
- 21
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UC Davis Medical Group | Sacramento | California | 95817 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| Christiana Care Health System | Newark | Delaware | 19718 | — |
| University of Florida - Health Shands | Gainesville | Florida | 32610 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| WellStar Kennestone Regional Medical Center | Marietta | Georgia | 30060 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Lexington VA Healthcare | Lexington | Kentucky | 40502 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| LSU Health Shreveport | Shreveport | Louisiana | 71103 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Spectrum Health Hospitals | Grand Rapids | Michigan | 49504 | — |
| Minneapolis Heart | Minneapolis | Minnesota | 55407 | — |
| Rutgers-Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08902 | — |
| Albany Medical Center | Albany | New York | 12208-3412 | — |
| Northwell Health | New Hyde Park | New York | 11040 | — |
| New York Presbyterian Hospital/Columbia University Medical Center | New York | New York | 10032 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Lehigh Valley Health Network | Allentown | Pennsylvania | 18103 | — |
| Hospital of University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| UT Erlanger | Chattanooga | Tennessee | 37403 | — |
| Memphis VA Medical Center | Memphis | Tennessee | 38104 | — |
| UT McGovern Medical School Memorial Hermann | Houston | Texas | 77030 | — |
| Baylor Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22903 | — |
| Inova Health Care Services | Falls Church | Virginia | 22042 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03255057, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2022 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03255057 live on ClinicalTrials.gov.