Efficacy and Safety Study of SHP647 as Induction Therapy in Participants With Moderate to Severe Ulcerative Colitis
Public ClinicalTrials.gov record NCT03259308. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Study of SHP647 as Induction Therapy in Subjects With Moderate to Severe Ulcerative Colitis (FIGARO UC 302)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy of SHP647 in inducing remission, based on composite score of patient-reported symptoms and centrally read endoscopy, in participants with moderate to severe ulcerative colitis (UC).
Study identification
- NCT ID
- NCT03259308
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 279 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 16 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 5, 2017 (Actual)
- Primary completion
- Jul 15, 2020 (Actual)
- Completion
- Oct 6, 2020 (Actual)
- Last update posted
- Apr 26, 2021
2017 – 2020
United States locations
- U.S. sites
- 62
- U.S. states
- 20
- U.S. cities
- 57
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Digestive Health Mesa - East | Mesa | Arizona | 85206 | — |
| Elite Clinical Studies - Phoenix - Clinedge - PPDS | Phoenix | Arizona | 85018 | — |
| Advanced Research Center | Anaheim | California | 92805 | — |
| Kindred Medical Institute for Clinical Trials, LLC | Corona | California | 92879 | — |
| United Medical Doctors | Encinitas | California | 92024 | — |
| University of California San Diego | La Jolla | California | 92037 | — |
| VA Long Beach Healthcare System - NAVREF - PPDS | Long Beach | California | 90822 | — |
| Facey Medical Foundation | Mission Hills | California | 91345 | — |
| United Medical Doctors | Murrieta | California | 92563 | — |
| Alliance Clinical Research-(Vestavia Hills) | Poway | California | 92064 | — |
| University of California San Francisco | San Francisco | California | 94158 | — |
| Care Access Research, San Pablo | San Pablo | California | 94806 | — |
| Renaissance Research Medical Group, INC | Cape Coral | Florida | 33991 | — |
| Gastro Florida | Clearwater | Florida | 33756 | — |
| Hi Tech and Global Research, LLc | Coral Gables | Florida | 33134 | — |
| ENCORE Borland-Groover Clinical Research - ERN - PPDS | Jacksonville | Florida | 32256 | — |
| SIH Research | Kissimmee | Florida | 34741 | — |
| Alliance Medical Research LLC | Lighthouse PT | Florida | 33064 | — |
| Sanchez Clinical Research, Inc | Miami | Florida | 33157 | — |
| Crystal Biomedical Research | Miami Lakes | Florida | 33065 | — |
| Pharma Research International Inc | Naples | Florida | 34110 | — |
| Bayside Clinical Research - New Port Richey | New Port Richey | Florida | 34655 | — |
| Accel Research Sites - St. Petersburg - ERN - PPDS | Pinellas Park | Florida | 33781 | — |
| BRCR Medical Center Inc. | Plantation | Florida | 33322 | — |
| DBC Research | Tamarac | Florida | 33321 | — |
| Infinite Clinical Trials | Atlanta | Georgia | 30349 | — |
| Atlanta Center For Gastroenterology PC | Decatur | Georgia | 30033 | — |
| Atlanta Gastroenterology Specialists, PC | Suwanee | Georgia | 30024 | — |
| Loretto Hospital | Chicago | Illinois | 60644 | — |
| IL Gastroenterology Group | Gurnee | Illinois | 60031 | — |
| Edward Hines Jr VA Hospital - NAVREF - PPDS | Hines | Illinois | 60141 | — |
| Dupage Medical Group | Oakbrook Terrace | Illinois | 60181 | — |
| Gastroenterology Associates of Hazard | Hazard | Kentucky | 41701 | — |
| CroNOLA, LLC. | Houma | Louisiana | 70360 | — |
| Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Commonwealth Clinical Studies LLC | Brockton | Massachusetts | 02302 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Clinical Research Institute of Michigan | Chesterfield | Michigan | 48047 | — |
| National Clinical, LLC | Hamtramck | Michigan | 48212 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| St Louis Center For Clinical Research | St Louis | Missouri | 63128 | — |
| Advanced Biomedical Research of America | Las Vegas | Nevada | 89123 | — |
| Encompass Care | North Las Vegas | Nevada | 89086 | — |
| NYU Langone Long Island Clinical Research Associates | Great Neck | New York | 11021 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Southtowns Gastroenterology, PLLC | Orchard Park | New York | 14127 | — |
| East Carolina Gastroenterology | Jacksonville | North Carolina | 28546 | — |
| Prestige Clinical Research | Franklin | Ohio | 45005 | — |
| Ohio Clinical Research Partners LLC | Mentor | Ohio | 44060 | — |
| Veteran's Research and Education Foundation - NAVREF - PPDS | Oklahoma City | Oklahoma | 73104 | — |
| Veterans Research Foundation of Pittsburgh - NAVREF - PPDS | Pittsburgh | Pennsylvania | 15240 | — |
| Digestive Health Associates of Texas, P.A.dba DHAT Research Institute | Garland | Texas | 75044 | — |
| Precision Research Institute, LLC | Houston | Texas | 77039 | — |
| Biopharma Informatic Inc. | Houston | Texas | 77043 | — |
| Southwest Clinical Trials | Houston | Texas | 77074 | — |
| Aztec Medical Research | Houston | Texas | 77079 | — |
| BI Research Center | Houston | Texas | 77084 | — |
| Southern Star Research Institute LLC | San Antonio | Texas | 78229 | — |
| Mid Atlantic Health Specialists | Galax | Virginia | 24333 | — |
| Winchester Gastroenterology Associates | Winchester | Virginia | 22601 | — |
| Mayo Clinic Health System - PPDS | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 145 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03259308, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 26, 2021 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03259308 live on ClinicalTrials.gov.