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Completed Phase 1 Interventional Results available

Epigenetic Reprogramming in Relapse/Refractory AML

ClinicalTrials.gov ID: NCT03263936

Public ClinicalTrials.gov record NCT03263936. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 21, 2026, 12:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Epigenetic Reprogramming in Relapse AML: A Phase 1 Study of Decitabine and Vorinostat Followed by Fludarabine, Cytarabine and G-CSF (FLAG) in Children and Young Adults With Relapsed/Refractory AML

Study identification

NCT ID
NCT03263936
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Therapeutic Advances in Childhood Leukemia Consortium
Other
Enrollment
37 participants

Conditions and interventions

Interventions

  • Cytarabine Drug
  • Decitabine Drug
  • Filgrastim (G-CSF) Drug
  • Fludarabine Drug
  • Vorinostat Drug

Drug

Eligibility (public fields only)

Age range
1 Year to 25 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 10, 2017
Primary completion
Jul 8, 2020
Completion
Feb 9, 2022
Last update posted
Oct 15, 2025

2017 – 2022

United States locations

U.S. sites
28
U.S. states
19
U.S. cities
25
Facility City State ZIP Site status
Children's Hospital Los Angeles Los Angeles California 90027
Children's Hospital Orange County Orange California 92868
UCSF School of Medicine San Francisco California 94158
The Children's Hospital, University of Colorado Aurora Colorado 80045
Children's National Medical Center Washington D.C. District of Columbia 20010
University of Miami Miami Florida 33136
All Children's Hospital St. Petersburg Florida 33701
Children's Healthcare of Atlanta, Emory University Atlanta Georgia 30322
Lurie Children's Hospital of Chicago Chicago Illinois 60611
Johns Hopkins University Baltimore Maryland 21231
Sidney Kimmel Cancer Center at Johns Hopkins Baltimore Maryland 21231
National Cancer Institute, Pediatric Oncology Branch Bethesda Maryland 20892
Dana-Farber Cancer Institute Boston Massachusetts 02215
C.S. Mott Children's Hospital Ann Arbor Michigan 48109-0914
CS Mott Children's Hospital, Ann Arbor Ann Arbor Michigan 48109
Children's Hospitals and Clinics of Minnesota Minneapolis Minnesota 55404
New York University Medical Center New York New York 10016
Children's Hospital New York-Presbyterian New York New York 10032
Levine Children's Hospital Charlotte North Carolina 28203
Cincinnati Children's Hospital Cincinnati Ohio 45229
Nationwide Children's Hospital Columbus Ohio 43205
Oregon Health and Science University Portland Oregon 97239
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Cook Children's Medical Center Fort Worth Texas 76104
Texas Children's Cancer Center, Baylor Houston Texas 77030
Primary Children's Hospital Salt Lake City Utah 84113
Seattle Children's Hospital Seattle Washington 98105
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03263936, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 15, 2025 · Synced May 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03263936 live on ClinicalTrials.gov.

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