A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis at Risk for Pulmonary Hypertension
Public ClinicalTrials.gov record NCT03267108. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Dose Escalation and Verification Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide (iNO) in Subjects at Risk of Pulmonary Hypertension Associated With Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2) - REBUILD
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A randomized, double-blind, placebo-controlled dose escalation and verification study to assess the safety and efficacy of pulsed inhaled nitric oxide (iNO) in subjects at risk for pulmonary hypertension associated with pulmonary fibrosis on long term oxygen therapy (Part 1 and Part 2) - REBUILD
Study identification
- NCT ID
- NCT03267108
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 145 participants
Conditions and interventions
Conditions
Interventions
- INOpulse® Combination Product
- Placebo Combination Product
- Open Label Extension Combination Product
Combination Product
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 14, 2020 (Actual)
- Primary completion
- Jun 9, 2023 (Actual)
- Completion
- Jun 30, 2023 (Actual)
- Last update posted
- Jul 27, 2023
2020 – 2023
United States locations
- U.S. sites
- 61
- U.S. states
- 27
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294 | — |
| Banner - University Medical Center Arizona | Phoenix | Arizona | 85006 | — |
| Arizona Pulmonary Specialists, Ltd. | Phoenix | Arizona | 85012 | — |
| University of California San Francisco | Fresno | California | 93701 | — |
| University of California | Los Angeles | California | 90024 | — |
| Amicis Research | Northridge | California | 91324 | — |
| Paloma Medical Group | Paloma | California | 92675 | — |
| University of California Davis Health | Sacramento | California | 95817 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| UC Denver Anschutz Medical Center | Aurora | Colorado | 80046 | — |
| National Jewish | Denver | Colorado | 80206 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| St. Francis Sleep Allergy and Lung Institute | Clearwater | Florida | 33765 | — |
| Advanced Pulmonary Research Institute | Loxahatchee Groves | Florida | 33470 | — |
| University of Miami | Miami | Florida | 33125 | — |
| Avanza Medical Research Center | Pensacola | Florida | 32503 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Cleveland Clinic | Weston | Florida | 33331 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| Piedmont Healthcare | Austell | Georgia | 30106 | — |
| Northwestern | Chicago | Illinois | 60611 | — |
| North Shore University Hospital | Evanston | Illinois | 60201 | — |
| Loyola University | Maywood | Illinois | 60153 | — |
| Southern Illinois University | Springfield | Illinois | 62702 / 62794 | — |
| Ascension St. Vincent Hospital | Indianapolis | Indiana | 46260 | — |
| Norton Pulmonary Specialists | Louisville | Kentucky | 40202 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21205 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| The Lung Research Center, LLC | Chesterfield | Missouri | 63017 | — |
| Creighton University | Omaha | Nebraska | 68124 | — |
| Atlantic Health Respiratory Institute | Summit | New Jersey | 07901 | — |
| NYU Langone | New York | New York | 10016 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Weill Cornell Medical Center | New York | New York | 10065 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| The University of North Carolina at Chapel Hill Marsico Clinical Research Center | Chapel Hill | North Carolina | 27517 | — |
| Pulmonix, LLC/LeBauer Cone Health | Greensboro | North Carolina | 27403 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| University Hospitals | Cleveland | Ohio | 44106 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| The Oregon Clinic | Portland | Oregon | 97220 | — |
| Thomas Jefferson University Korman Respiratory Institute | Philadelphia | Pennsylvania | 19017 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15123 | — |
| AnMed Health | Anderson | South Carolina | 29621 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Metroplex Pulmonary and Sleep | McKinney | Texas | 75069 | — |
| University of Utah Health Sciences | Salt Lake City | Utah | 84108 | — |
| Inova Heart and Vascular Institute Advanced Lung Disease Clinic | Falls Church | Virginia | 22042 | — |
| Pulmonary Associates of Richmond | Richmond | Virginia | 23229 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03267108, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 27, 2023 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03267108 live on ClinicalTrials.gov.