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Completed Phase 1 Interventional

Study of bb21217 in Multiple Myeloma

ClinicalTrials.gov ID: NCT03274219

Public ClinicalTrials.gov record NCT03274219. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 8:14 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study of bb21217, an Anti-BCMA CAR T Cell Drug Product, in Relapsed and/or Refractory Multiple Myeloma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Study CRB-402 is a 2-part, non-randomized, open label, multi-site Phase 1 study of bb21217 in adults with relapsed/refractory multiple myeloma (MM).

Study identification

NCT ID
NCT03274219
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
2seventy bio
Industry
Enrollment
72 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 16, 2017 (Actual)
Primary completion
Dec 2, 2022 (Actual)
Completion
Dec 2, 2022 (Actual)
Last update posted
Nov 7, 2023

2017 – 2022

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
9
Facility City State ZIP Site status
UCSF Medical Center at Parnassus San Francisco California 94143 —
H. Lee Moffitt Cancer Center Tampa Florida 33612 —
Winship Cancer Insitute, Emory University Atlanta Georgia 30322 —
University of Chicago Chicago Illinois 60637 —
Massachusetts General Hospital Cancer Center Boston Massachusetts 02144 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
Dana-Farber Cancer Institute Boston Massachusetts 02215 —
Mayo Clinic Cancer Center Rochester Minnesota 55905 —
John Theurer Cancer Center at Hackensack UMC Hackensack New Jersey 07601 —
Mount Sinai Medical Center New York New York 10029 —
Sarah Cannon Research Institute Nashville Tennessee 37203 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03274219, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 7, 2023 · Synced Oct 27, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03274219 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →