ClinicalTrials.gov record
Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo
ClinicalTrials.gov ID: NCT03281954
Public ClinicalTrials.gov record NCT03281954. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 2:37 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo
Study identification
- NCT ID
- NCT03281954
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- NSABP Foundation Inc
- Network
- Enrollment
- 1,550 participants
Conditions and interventions
Conditions
Interventions
- Atezolizumab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 18, 2017
- Primary completion
- Dec 30, 2024
- Completion
- Nov 29, 2027
- Last update posted
- Apr 7, 2024
2017 – 2027
United States locations
- U.S. sites
- 212
- U.S. states
- 32
- U.S. cities
- 167
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Mitchell Cancer Institute | Mobile | Alabama | 36604 | — |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | — |
| St. Bernard's Medical Center | Jonesboro | Arkansas | 72401 | — |
| St. Bernard's Medical Center | Paragould | Arkansas | 72450 | — |
| Kaiser Permanente-Anaheim | Anaheim | California | 92806 | — |
| Kaiser Permanente-Baldwin Park | Baldwin Park | California | 91706 | — |
| Kaiser Permanente-Bellflower | Bellflower | California | 90706 | — |
| Arrowhead Regional Medical Center | Colton | California | 92324 | — |
| City of Hope | Duarte | California | 91010 | — |
| Kaiser Permanente-Fontana | Fontana | California | 92335 | — |
| Kaiser Permanente-Harbor City | Harbor City | California | 90710 | — |
| Kaiser Permanente-Irvine | Irvine | California | 92618 | — |
| Cancer and Blood Specialty Clinic | Los Alamitos | California | 90720 | — |
| Kaiser Permanente-Sunset | Los Angeles | California | 90027 | — |
| Kaiser Permanente-West Los Angeles | Los Angeles | California | 90034 | — |
| Kaiser Permanente-Panorama City | Panorama City | California | 91402 | — |
| Kaiser Permanente-Riverside | Riverside | California | 92505 | — |
| Kaiser Permanente Medical Group | San Diego | California | 92108 | — |
| Kaiser Permanente-Zion | San Diego | California | 92120 | — |
| Kaiser Permanente - Otay | San Diego | California | 92153 | — |
| Kaiser Permanente- San Marcos | San Marcos | California | 92078 | — |
| City of Hope - South Pasadena | South Pasadena | California | 91030 | — |
| Torrance Memorial Physician Network | Torrance | California | 90505 | — |
| City of Hope - Upland | Upland | California | 91786 | — |
| PIH Health | Whittier | California | 90602 | — |
| Kaiser Permanente-Woodland Hills | Woodland Hills | California | 91367 | — |
| Mount Sinai Comprehensive Cancer Center Aventura | Aventura | Florida | 33180 | — |
| Memorial Healthcare System Office of Human Research | Hollywood | Florida | 33021 | — |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| UF Health Cancer Center at Orlando Health | Orlando | Florida | 32806 | — |
| Gwinnett Hospital System Center for Cancer Care | Duluth | Georgia | 30096 | — |
| Gwinnett Hospital System Center for Cancer Care | Lawrenceville | Georgia | 30046 | — |
| Gwinnett Hospital System Center for Cancer Care | Snellville | Georgia | 30078 | — |
| Illinois Cancer Care-Bloomington | Bloomington | Illinois | 61704 | — |
| John H. Stroger, Jr. Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Affiliated Oncologists | Chicago Ridge | Illinois | 60415 | — |
| Cancer Care Specialists of Central Illinois | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Emhurst Memorial Nancy W. Knowles Cancer Center | Elmhurst | Illinois | 60126 | — |
| Illinois Cancer Care-Galesburg | Galesburg | Illinois | 61401 | — |
| Edward Cancer Center | Naperville | Illinois | 60540 | — |
| Illinois Cancer Care-Ottawa | Ottawa | Illinois | 61350 | — |
| Illinois Cancer Care PC | Peoria | Illinois | 61615 | — |
| Illinois Cancer Care-Peru | Peru | Illinois | 61354 | — |
| Edward Cancer Center Plainfield | Plainfield | Illinois | 60585 | — |
| Cancer Care Specialists of Central Illinois-Swansea | Swansea | Illinois | 62226 | — |
| Fort Wayne Medical Oncology and Hematology Inc (W. Jefferson Blvd) | Fort Wayne | Indiana | 46804 | — |
| Fort Wayne Medical Oncology and Hematology Inc (Parkview Plaza) | Fort Wayne | Indiana | 46845 | — |
| Mercy Medical Center Hall-Perrine Cancer Center | Cedar Rapids | Iowa | 52403 | — |
| Cancer Center of Kansas - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas - Dodge City | Dodge City | Kansas | 67801 | — |
| Susan B. Allen Memorial Hosptial | El Dorado | Kansas | 67042 | — |
| Cancer Center at Mercy - W. Laurel | Independence | Kansas | 67301 | — |
| Kingman Community Hospital | Kingman | Kansas | 67068 | — |
| Southwest Medical Center | Liberal | Kansas | 67901 | — |
| McPherson Center for Health | McPherson | Kansas | 67460 | — |
| Newton Medical Center | Newton | Kansas | 67114 | — |
| Labette Health | Parsons | Kansas | 67357 | — |
| Pratt Regional Medical Center | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas - Salina | Salina | Kansas | 67401 | — |
| Cancer Center of Kansas - Wichita | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| Winfield Healthcare Center | Winfield | Kansas | 67156 | — |
| Norton Cancer Institute-Downtown | Louisville | Kentucky | 40202 | — |
| Norton Cancer Institute-Norton Healthcare Pavilion | Louisville | Kentucky | 40202 | — |
| University of Louisville-James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Baptist Health Louisville; Consultants in Blood Disorders and Cancer | Louisville | Kentucky | 40207 | — |
| Norton Cancer Institute-St Matthews | Louisville | Kentucky | 40207 | — |
| Norton Cancer Institute-Brownsboro | Louisville | Kentucky | 40241 | — |
| Ochsner Medical Center-Kenner | Kenner | Louisiana | 70065 | — |
| West Jefferson Medical Center Cancer Center | Marrero | Louisiana | 70072 | — |
| University Medical Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Medstar Union Memorial Hospital | Baltimore | Maryland | 21218 | — |
| Harry and Jeanette Weinberg Cancer Center at Franklin Square | Baltimore | Maryland | 21237 | — |
| Maryland Oncology Hematology | Bethesda | Maryland | 20817 | — |
| Maryland Oncology - Hematology Brandywine | Brandywine | Maryland | 20613 | — |
| Maryland Oncology - Hematology PA | Columbia | Maryland | 21044 | — |
| Maryland Oncology - Hematology Frederick | Frederick | Maryland | 21702 | — |
| Meritus Center for Clinical Research | Hagerstown | Maryland | 21742 | — |
| Maryland Oncology - Hematology PA | Lanham | Maryland | 20706 | — |
| Maryland Oncology Hematology | Rockville | Maryland | 20850 | — |
| Capital Hematology Oncology Associates | Silver Spring | Maryland | 20904 | — |
| Holy Cross Hospital | Silver Spring | Maryland | 20910 | — |
| University of Maryland, St. Joseph Medical Center | Towson | Maryland | 21204 | — |
| Maryland Oncology Hematology | Wheaton | Maryland | 20902 | — |
| Berkshire Hematology Oncology Services at Berkshire Medical Center Cancer and Infusion Center | Pittsfield | Massachusetts | 01201 | — |
| Henry Ford Cancer Institute Brownstown | Brownstown | Michigan | 48183 | — |
| Henry Ford Cancer Institute Macomb Hospital | Clinton Township | Michigan | 48038 | — |
| Henry Ford Medical Center Fairlane | Dearborn | Michigan | 48126 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Michigan State University | East Lansing | Michigan | 48823 | — |
| Henry Ford Allegiance Health | Jackson | Michigan | 49201 | — |
| Michigan State University-Breslin Cancer Center | Lansing | Michigan | 48910 | — |
| Henry Ford Medical Center Columbus | Novi | Michigan | 48377 | — |
| Henry Ford Hospital W Bloomfield | West Bloomfield | Michigan | 48322 | — |
| Henry Ford Cancer Institute Wyandotte Hospital | Wyandotte | Michigan | 48192 | — |
| University of Missouri-Ellis Fischel Cancer Center | Columbia | Missouri | 65212 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| MD Anderson Cancer Center at Cooper | Voorhees Township | New Jersey | 08043 | — |
| New York Oncology Hematology PC | Albany | New York | 12206 | — |
| Broome Oncolgy | Binghamton | New York | 13905 | — |
| Broome Oncology | Johnson City | New York | 13790 | — |
| Health Quest Medical Practice | Poughkeepsie | New York | 12601 | — |
| Vassar Brothers Medical Center | Poughkeepsie | New York | 12601 | — |
| RHOA of Cary | Cary | North Carolina | 27518 | — |
| Waverly Hematology Oncology | Cary | North Carolina | 27518 | — |
| Carolinas Medical Center-Levine Cancer Insitute | Charlotte | North Carolina | 28204 | — |
| Levine Cancer Center Institute Pineville | Charlotte | North Carolina | 28210 | — |
| RHOA of Garner | Garner | North Carolina | 27529 | — |
| UNC Regional Physicians Hematology and Oncolgoy | High Point | North Carolina | 27262 | — |
| FirstHealth of the Carolinas FirstHealth Outpatient Cancer Center | Pinehurst | North Carolina | 28374 | — |
| Rex Cancer Center | Raleigh | North Carolina | 27607 | — |
| RHOA of Blue Ridge | Raleigh | North Carolina | 27607 | — |
| RCC of Wakefield | Raleigh | North Carolina | 27614 | — |
| Nash UNC Health Care - Danny Talbott Cancer Center | Rocky Mount | North Carolina | 28704 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| Aultman Alliance Cancer Center | Alliance | Ohio | 44601 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Aultman Medical Group Hematology and Oncology | Canton | Ohio | 44710 | — |
| The Ohio State University Wexner Medical Center-Investigational Drug Service Oncology | Columbus | Ohio | 43210 | — |
| The Stephanie Speilman Comprehensive Breast Center | Columbus | Ohio | 43212 | — |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | 97401 | — |
| Kaiser Permanente Northwest-Oncology/Hematology | Portland | Oregon | 97227 | — |
| Northwest Cancer Specialists | Tigard | Oregon | 97223 | — |
| UPMC Hillman Cancer Center-Beaver | Beaver | Pennsylvania | 15009 | — |
| UPMC Hillman Cancer Center - Passavant North | Cranberry Township | Pennsylvania | 16066 | — |
| Ephrata Cancer Center | Ephrata | Pennsylvania | 17522 | — |
| Allegheny Cancer Institute St. Vincent | Erie | Pennsylvania | 16505 | — |
| St. Vincent Hospital | Erie | Pennsylvania | 16544 | — |
| UPMC Cancer Center Horizon | Farrell | Pennsylvania | 16121 | — |
| Wellspan Medical Oncology | Gettysburg | Pennsylvania | 17325 | — |
| UPMC Hillman Cancer Center- Mountain View | Greensburg | Pennsylvania | 15601 | — |
| UPMC Cancer Center Greenville | Greenville | Pennsylvania | 16125 | — |
| AHN Cancer Institute at Jefferson | Jefferson Hills | Pennsylvania | 15025 | — |
| Seechler Family Cancer Center | Lebanon | Pennsylvania | 17042 | — |
| Forbes Regional Hospital | Monroeville | Pennsylvania | 15146 | — |
| UPMC Hillman Cancer Center UPMC East-Monroeville | Monroeville | Pennsylvania | 15146 | — |
| UPMC Hillman Cancer Center Norwin | N. Huntingdon | Pennsylvania | 15642 | — |
| UPMC Hillman Cancer Center New Castle | New Castle | Pennsylvania | 16105 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| WPAON at AGH | Pittsburgh | Pennsylvania | 15212 | — |
| WPAON at WPH | Pittsburgh | Pennsylvania | 15212 | — |
| Magee-Women's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| UPCI Investigational Drug Services | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC Hillman Cancer Center @ Passavant - HOA | Pittsburgh | Pennsylvania | 15237 | — |
| UPMC Hillman Cancer Center @ Passavant - OHA | Pittsburgh | Pennsylvania | 15237 | — |
| UPMC Hillman Cancer Center-Upper Saint Clair | Pittsburgh | Pennsylvania | 15243 | — |
| UPMC Cancer Center Northwest | Seneca | Pennsylvania | 16346 | — |
| UPMC Hillman Cancer Center - Uniontown | Uniontown | Pennsylvania | 15401 | — |
| UPMC Hillman Cancer Center-Washington | Washington | Pennsylvania | 15301 | — |
| Wexford Health & Wellness Pavilion | Wexford | Pennsylvania | 15090 | — |
| Cancer Care Associates of York | York | Pennsylvania | 17403 | — |
| Wellspan Health-York Cancer Center Oncology Research | York | Pennsylvania | 17403 | — |
| Women's and Infants Hospital | Providence | Rhode Island | 02905 | — |
| Gibbs Cancer Center and Research Institute - Pelham | Greer | South Carolina | 29651 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Avera Cancer Institute-Sioux Falls | Sioux Falls | South Dakota | 57105 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Wellmont Cancer Institute | Johnson City | Tennessee | 37601 | — |
| Wellmont Cancer Institute | Kingsport | Tennessee | 37660 | — |
| Dell Seton Medical Center at the University of Texas-Seton Infusion Center | Austin | Texas | 72701 | — |
| Texas Oncology Bedford | Bedford | Texas | 76022 | — |
| Texas Oncology Carrollton | Carrollton | Texas | 75010 | — |
| Texas Oncology - Methodist Dallas Cancer Center | Dallas | Texas | 75203 | — |
| Texas Oncology - Medical City Dallas | Dallas | Texas | 75230 | — |
| Texas Oncology Dallas Presbyterian Hospital | Dallas | Texas | 75231 | — |
| Texas Oncology Denton | Denton | Texas | 76201 | — |
| Texas Oncology Flower Mound | Flower Mound | Texas | 75028 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Houston Methodist Cancer Center | Houston | Texas | 77030 | — |
| Harris Health System-Smith Clinic | Houston | Texas | 77054 | — |
| Texas Oncology - McAllen South Second | McAllen | Texas | 78503 | — |
| Texas Oncology Midland Allison Cancer Center | Midland | Texas | 79701 | — |
| Texas Oncology Plano | Plano | Texas | 75075 | — |
| Texas Oncology - The Woodlands | The Woodlands | Texas | 77380 | — |
| Wellmont Medical Associates-Oncology and Hematology | Bristol | Virginia | 24201 | — |
| Virginia Cancer Care Specialist | Leesburg | Virginia | 20176 | — |
| Centra Lynchburg Hematology Oncology | Lynchburg | Virginia | 24501 | — |
| Bon Secours Richmond Community Hospital Medical Oncology Associates at Memorial Regional Medical Center | Mechanicsville | Virginia | 23116 | — |
| Bon Secours St Francis Medical Center | Midlothian | Virginia | 23114 | — |
| Southwest Virginia Regional Cancer Center | Norton | Virginia | 24273 | — |
| Bon Secours Richmond Community Hospital Oncology Associates at St. Mary's Hospital | Richmond | Virginia | 23226 | — |
| MRCC Auburn | Auburn | Washington | 98001 | — |
| MRCC Gig Harbor | Gig Harbor | Washington | 98335 | — |
| MRCC Puyallup | Puyallup | Washington | 98372 | — |
| MultiCare Health System | Tacoma | Washington | 98405 | — |
| MultiCare Institute for Research & Innovation | Tacoma | Washington | 98405 | — |
| CAMC Health Education and Research Institute | Charleston | West Virginia | 25304 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
| Aurora Cancer Care-Southern Lakes | Burlington | Wisconsin | 53105 | — |
| Aurora Health Center Fond du Lac | Fond du Lac | Wisconsin | 54937 | — |
| Aurora Cancer Care-Germantown Health Center | Germantown | Wisconsin | 53022 | — |
| Aurora Cancer Care-Grafton | Grafton | Wisconsin | 53024 | — |
| Aurora BayCare Medical Center | Green Bay | Wisconsin | 54311 | — |
| Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | 53142 | — |
| Aurora Cancer Care | Milwaukee | Wisconsin | 53209 | — |
| Aurora Cancer Care-Milwaukee South | Milwaukee | Wisconsin | 53215 | — |
| Aurora St. Lukes Medical Center-Pharmacy Only | Milwaukee | Wisconsin | 53215 | — |
| Aurora West Allis Medical Center | Milwaukee | Wisconsin | 53227 | — |
| Aurora Sinai Medical Center | Milwaukee | Wisconsin | 53233 | — |
| Vince Lombardi Cancer Clinic Oshkosh | Oshkosh | Wisconsin | 54904 | — |
| Aurora Cancer Care-Racine | Racine | Wisconsin | 53406 | — |
| Vince Lombardi Cancer Clinic Sheboygan | Sheboygan | Wisconsin | 53081 | — |
| Aurora Medical Center in Summit | Summit | Wisconsin | 53066 | — |
| Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | 54241 | — |
| Aurora Cancer Care | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03281954, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 7, 2024 · Synced May 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03281954 live on ClinicalTrials.gov.