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Completed Phase 2Phase 3 Interventional Results available

Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder

ClinicalTrials.gov ID: NCT03299166

Public ClinicalTrials.gov record NCT03299166. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 9:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Trial of Adjunctive Troriluzole in Obsessive Compulsive Disorder

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy of troriluzole as adjunctive therapy versus placebo in participants with obsessive compulsive disorder (OCD) who had an inadequate response to selective serotonin reuptake inhibitor (SSRI), clomipramine, venlafaxine, or desvenlafaxine treatment

Study identification

NCT ID
NCT03299166
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Biohaven Pharmaceuticals, Inc.
Industry
Enrollment
426 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 19, 2017 (Actual)
Primary completion
Jun 2, 2020 (Actual)
Completion
Dec 8, 2025 (Actual)
Last update posted
Jan 22, 2026

2017 – 2025

United States locations

U.S. sites
57
U.S. states
24
U.S. cities
55
Facility City State ZIP Site status
Metropolitan Neuro Behavioral Institute Chandler Arizona 85226 —
Preferred Research Partners, Inc. Little Rock Arkansas 72211 —
Collaborative Neuroscience Network, LLC Garden Grove California 92845 —
University of California San Diego La Jolla California 92037 —
Synergy Research San Diego Lemon Grove California 91945 —
CalNeuro Research Group Los Angeles California 90024 —
Pacific Research Partners, LLC Oakland California 94607 —
NRC Research Institute Orange California 92868 —
Desert Valley Research Rancho Mirage California 92270 —
Artemis Institute for Clinical Research San Diego California 92103 —
Artemis Institute for Clinical Research San Marcos California 92078 —
Stanford University, Department of Psychiatry and Behavioral Sciences Stanford California 94305-5717 —
Pacific Clinical Research Medical Group Upland California 91786 —
Mountain View Clinical Research, Inc. Denver Colorado 80209 —
Institute of Living / Hartford Hospital Hartford Connecticut 06106 —
Yale University New Haven Connecticut 06519 —
Comprehensive Psychiatric Care Norwich Connecticut 06360 —
Gulfcoast Clinical Research Center Fort Myers Florida 33912 —
University of Florida Department of Psychiatry Gainesville Florida 32606 —
Galiz Research Hialeah Florida 33016 —
Clinical Neuroscience Solutions, Inc Jacksonville Florida 32256 —
SIH Research, Inc Kissimmee Florida 34741 —
Harmony Clinical Research North Miami Beach Florida 33162 —
Medical Research Group of Central Florida Orange City Florida 32763 —
Clinical Neuroscience Solutions, Inc Orlando Florida 32801 —
iResearch Atlanta, LLC Decatur Georgia 30030 —
iResearch Savannah Savannah Georgia 31405 —
Chicago Research Center Chicago Illinois 60634 —
University of Chicago Department of Psychiatry & Behavioral Neuroscience Chicago Illinois 60637 —
AMR-Baber Research, Inc Naperville Illinois 60563 —
Phoenix Medical Research, Inc. Prairie Village Kansas 66208 —
Heartland Research Associates, LLC Wichita Kansas 67207 —
Pharmasite Research, Inc. Pikesville Maryland 21208 —
McLean Hospital Belmont Massachusetts 02478 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Boston Clinical Trials Boston Massachusetts 02131 —
Michigan Clinical Research PC Ann Arbor Michigan 48105 —
Precise Research Centers Flowood Mississippi 39232 —
ActivMed Practices and Research, Inc. Portsmouth New Hampshire 03801 —
Center for Emotional Fitness Cherry Hill New Jersey 08028 —
Integrative Clinical Trials LLC Brooklyn New York 11229 —
Bio Behavioral Institute Great Neck New York 11021 —
New York State Psychiatric Institute New York New York 10032 —
Finger Lakes Clinical Research Rochester New York 14618 —
Richmond Behavioral Associates Staten Island New York 10312 —
New Hope Clinical Research Charlotte North Carolina 28211 —
New Horizons Clinical Research Cincinnati Ohio 45242 —
Midwest Clinical Research Center Dayton Ohio 45417 —
Summit Research Network (Oregon) Inc. Portland Oregon 97210 —
Suburban Research Associates Media Pennsylvania 19063 —
University of Pennsylvania Philadelphia Pennsylvania 19104 —
Clinical Neuroscience Solutions, Inc. Memphis Tennessee 38119 —
FutureSearch Trials of Dallas, LP Dallas Texas 75231 —
InSite Clinical Research DeSoto Texas 75115 —
Baylor College of Medicine Houston Texas 77030 —
Psychiatric Alliance of the Blue Ridge, Inc. Charlottesville Virginia 22903 —
Northwest Clinical Research Center Bellevue Washington 98007 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03299166, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 22, 2026 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT03299166 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →