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Terminated Phase 3 Interventional Results available

WAveCrest Vs. Watchman TranssEptal LAA Closure to REduce AF-Mediated STroke 2

ClinicalTrials.gov ID: NCT03302494

Public ClinicalTrials.gov record NCT03302494. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

WAveCrest Vs. Watchman TranssEptal LAA Closure to REduce AF-Mediated STroke 2. A Prospective, Multicenter, Randomized, Active Controlled, Clinical Trial of the Coherex WaveCrest® Left Atrial Appendage Occlusion System Compared to the Watchman® LAA Closure Device for the Reduction in Risk of Ischemic Stroke or Systemic Embolism in Subjects With Non-valvular Atrial Fibrillation That Have an Appropriate Rationale to Seek a Non-pharmacologic Alternative to Chronic Oral Anticoagulation.

Study identification

NCT ID
NCT03302494
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Coherex Medical
Industry
Enrollment
248 participants

Conditions and interventions

Conditions

Interventions

  • Coherex WaveCrest® Left Atrial Appendage Occlusion System Device
  • Watchman® LAA Closure Device Device

Device

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 26, 2017
Primary completion
Dec 20, 2023
Completion
Dec 20, 2023
Last update posted
Mar 11, 2025

2017 – 2023

United States locations

U.S. sites
23
U.S. states
15
U.S. cities
21
Facility City State ZIP Site status
Grandview Medical Center Birmingham Alabama 35243
Dignity Health Mercy Gilbert Medical Center Chandler Arizona 85224
Pacific Heart Institute / St. John's Health Center Los Angeles California 90033
Medstar Heart and Vascular Institute - Washington Hospital Center Washington D.C. District of Columbia 20010
St. Vincent's Medical Center Jacksonville Florida 32204
Piedmont Heart Institute Atlanta Georgia 30309
Wellstar Kennestone Marietta Georgia 30060
Baptist Health Lexington Lexington Kentucky 40503
MedStar Union Memorial Hospital Baltimore Maryland 21218
Marquette General Hospital Marquette Michigan 49855
Munson Medical Center Traverse City Michigan 49684
Cardiology Associates Research, LLC Tupelo Mississippi 38801
Northwell Health Bay Shore New York 11706
New York University- NYU Langone Cardiac New York New York 10016
New York University New York New York 10016
Icahn School of Medicine at Mount Sinai New York New York 10029
Ohio State University Columbus Ohio 43210
UPMC Pinnacle Health Cardiovascular Institute Harrisburg Pennsylvania 17104
Texas Cardiac Arrhythmia Research Foundation Austin Texas 78705
Baylor Scott & White All Saints Medical Center Fort Worth Texas 76104
Heart Hospital Baylor Plano (Baylor Research Institute) Plano Texas 75093
Christus Trinity Clinic Research Tyler Texas 75702
Virginia Commonwealth University Richmond Virginia 23298

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03302494, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 11, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03302494 live on ClinicalTrials.gov.

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