Safety and Efficacy of SGN-LIV1A Plus Pembrolizumab for Patients With Locally-Advanced or Metastatic Triple-Negative Breast Cancer
Public ClinicalTrials.gov record NCT03310957. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Single Arm, Open Label Phase 1b/2 Study of SGN-LIV1A in Combination With Pembrolizumab for First-Line Treatment of Patients With Unresectable Locally-Advanced or Metastatic Triple-Negative Breast Cancer
Study identification
- NCT ID
- NCT03310957
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Seagen Inc.
- Industry
- Enrollment
- 185 participants
Conditions and interventions
Conditions
Interventions
- ladiratuzumab vedotin Drug
- Pembrolizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 26, 2018
- Primary completion
- Sep 29, 2024
- Completion
- Sep 29, 2024
- Last update posted
- Dec 11, 2025
2018 – 2024
United States locations
- U.S. sites
- 26
- U.S. states
- 18
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| Cedars Sinai Medical Center / Samuel Oschin Comprehensive Cancer Institute | Los Angeles | California | 90048 | — |
| Chao Family Comprehensive Cancer Center University of California Irvine | Orange | California | 92868 | — |
| University of California Irvine - Newport | Orange | California | 92868 | — |
| Rocky Mountain Cancer Centers - Aurora | Aurora | Colorado | 80012 | — |
| The Whittingham Cancer Center / Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Helen F. Graham Cancer Center / Christiana Care Health Systems | Newark | Delaware | 19713 | — |
| Miami Cancer Institute at Baptist Health, Inc. | Miami | Florida | 33176 | — |
| AdventHealth Cancer Institute | Orlando | Florida | 32804 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Piedmont Cancer Institute | Atlanta | Georgia | 30309 | — |
| Winship Cancer Institute / Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Ingalls Cancer Care / Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Cardinal Bernardin Cancer Center / Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Allina Health Cancer Institute | Minneapolis | Minnesota | 55407 | — |
| Saint Luke's Cancer Institute LLC | Kansas City | Missouri | 64111 | — |
| Summit Medical Group | Florham Park | New Jersey | 07932 | — |
| New Mexico Cancer Center | Albuquerque | New Mexico | 87131 | — |
| Weill Cornell Medicine | New York | New York | 10065 | — |
| University of Pittsburgh Medical Center (UPMC)/Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Texas Oncology - DFW | Dallas | Texas | 75246 | — |
| Texas Oncology - Houston Memorial City | Houston | Texas | 77024 | — |
| Texas Oncology - San Antonio Medical Center Northeast | San Antonio | Texas | 78212 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
| Fred Hutchinson Cancer Center / Seattle Cancer Care Alliance / University of Washington | Seattle | Washington | 98109-1023 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03310957, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 11, 2025 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03310957 live on ClinicalTrials.gov.