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Completed Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Belimumab Administered in Combination With Rituximab to Adult Subjects With Systemic Lupus Erythematosus (SLE) - BLISS-BELIEVE

ClinicalTrials.gov ID: NCT03312907

Public ClinicalTrials.gov record NCT03312907. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 10:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, 104-Week Study to Evaluate the Efficacy and Safety of Belimumab Administered in Combination With Rituximab to Adult Subjects With Systemic Lupus Erythematosus (SLE)

Study identification

NCT ID
NCT03312907
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
292 participants

Conditions and interventions

Interventions

  • Belimumab Drug
  • Rituximab Drug
  • Rituximab-placebo Drug
  • Standard therapy (Excluding Immunosuppressants) Drug
  • Standard therapy (Including Immunosuppressants) Drug
  • Steroid Taper Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2018
Primary completion
May 28, 2020
Completion
Jul 6, 2021
Last update posted
Feb 17, 2025

2018 – 2021

United States locations

U.S. sites
28
U.S. states
15
U.S. cities
25
Facility City State ZIP Site status
GSK Investigational Site Birmingham Alabama 35294
GSK Investigational Site La Mesa California 92020
GSK Investigational Site San Leandro California 94578
GSK Investigational Site Upland California 91786
GSK Investigational Site Denver Colorado 80230
GSK Investigational Site Aventura Florida 33180
GSK Investigational Site Miami Florida 33136
GSK Investigational Site Orlando Florida 32806-6264
GSK Investigational Site Tamarac Florida 33321
GSK Investigational Site Tampa Florida 33613
GSK Investigational Site Tampa Florida 33614
GSK Investigational Site Ann Arbor Michigan 48109-5542
GSK Investigational Site Brighton Michigan 48116
GSK Investigational Site Lansing Michigan 48910
GSK Investigational Site Lansing Michigan 48917
GSK Investigational Site Las Cruces New Mexico 88011
GSK Investigational Site Manhasset New York 11030
GSK Investigational Site New York New York 10016
GSK Investigational Site New York New York 10032
GSK Investigational Site Charlotte North Carolina 28204
GSK Investigational Site Vandalia Ohio 45377
GSK Investigational Site Oklahoma City Oklahoma 73102
GSK Investigational Site Pittsburgh Pennsylvania 15224
GSK Investigational Site Summerville South Carolina 29486
GSK Investigational Site Austin Texas 78731
GSK Investigational Site League City Texas 77573
GSK Investigational Site Spokane Washington 99204
GSK Investigational Site Glendale Wisconsin 53217

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 51 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03312907, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 17, 2025 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03312907 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →