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Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Trial To Evaluate A Multivalent Pneumococcal Conjugate Vaccine In Healthy Adults 50-85 Years Of Age

ClinicalTrials.gov ID: NCT03313050

Public ClinicalTrials.gov record NCT03313050. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 1:59 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 1/2, RANDOMIZED, OBSERVER-BLINDED TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF A MULTIVALENT PNEUMOCOCCAL CONJUGATE VACCINE IN HEALTHY ADULTS 50 THROUGH 85 YEARS OF AGE

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a 2-stage, phase 1/2, randomized, active-controlled, observer-blinded study with a 2-arm parallel design in each stage. In Stage 1 healthy adults 50 to 64 years of age with no history of pneumococcal vaccination will be randomized equally to receive either a single intramuscular dose of multivalent pneumococcal conjugate vaccine or a licensed tetanus, diphtheria, acellular pertussis combination vaccine (Tdap) (control group). In Stage 2 healthy adults 65 to 85 years of age previously vaccinated with Prevnar 13 \>=2 months prior to investigational product administration will be randomized equally to receive either a single intramuscular dose of multivalent pneumococcal conjugate vaccine or the licensed 23-valent pneumococcal polysaccharide vaccine (control group).

Study identification

NCT ID
NCT03313050
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
511 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 11, 2017
Primary completion
May 23, 2019
Completion
May 23, 2019
Last update posted
Jun 3, 2020

2017 – 2019

United States locations

U.S. sites
18
U.S. states
10
U.S. cities
15
Facility City State ZIP Site status
Achieve Clinical Research LLC Birmingham Alabama 35216
Core Healthcare Group Cerritos California 90703
Meridian Clinical Research, LLC Savannah Georgia 31406
Augusta Family Practice Augusta Kansas 67010
Heartland Research Associates, LLC Augusta Kansas 67010
Axtell Clinic, P.A. Newton Kansas 67114
Heartland Research Associates, LLC Newton Kansas 67114
Heartland Research Associates, LLC Wichita Kansas 67205
Kentucky Pediatric/Adult Research Bardstown Kentucky 40004
Meridian Clinical Research, LLC Norfolk Nebraska 68701
Meridian Clinical Research LLC Omaha Nebraska 68134
PMG Research of Charlotte, LLC Charlotte North Carolina 28209
PMG Research of Wilmington, LLC Wilmington North Carolina 28401
Omega Medical Research Warwick Rhode Island 02886
Medical Research South, LLC Goose Creek South Carolina 29445
J. Lewis Research Incorporated, Foothill Family Clinic Salt Lake City Utah 84109
J. Lewis Research, Incorporated/Foothill Family Clinic South Salt Lake City Utah 84121
Advanced Clinical Research West Jordan Utah 84088

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03313050, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 3, 2020 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03313050 live on ClinicalTrials.gov.

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