Safety and Efficacy Study of RA101495 in Subjects With Generalized Myasthenia Gravis
Public ClinicalTrials.gov record NCT03315130. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of RA101495 in Subjects With Generalized Myasthenia Gravis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to evaluate the safety and efficacy of RA101495 in patients with generalized Myasthenia Gravis (gMG). Subjects will be randomized in a 1:1:1 ratio to receive daily SC doses of 0.1 mg/kg RA101495, 0.3 mg/kg RA101495, or matching placebo for 12 weeks.
Study identification
- NCT ID
- NCT03315130
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 45 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 11, 2017 (Actual)
- Primary completion
- Dec 10, 2018 (Actual)
- Completion
- Nov 19, 2020 (Actual)
- Last update posted
- Jul 27, 2022
2017 – 2020
United States locations
- U.S. sites
- 26
- U.S. states
- 19
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Diagnostic and Medical Clinic - Mobile | Mobile | Alabama | 36604 | — |
| The Research Center of Southern California | Carlsbad | California | 92011 | — |
| UCLA Medical Center | Los Angeles | California | 90095 | — |
| University of California Irvine Health ALS and Neuromuscular Center | Orange | California | 92868 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| George Washington University | Washington D.C. | District of Columbia | 20052 | — |
| University of Florida | Jacksonville | Florida | 32209 | — |
| University of South Florida | Tampa | Florida | 33620 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Wayne State University | Detroit | Michigan | 48202 | — |
| Michigan State University | East Lansing | Michigan | 48864 | — |
| University of Buffalo | Buffalo | New York | 14260 | — |
| Hospital for Special Surgery | New York | New York | 10021 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Allegheny Neurological Associates | Pittsburgh | Pennsylvania | 15212 | — |
| Wesley Neurology Clinic | Cordova | Tennessee | 38018 | — |
| University of Texas Southwestern | Dallas | Texas | 75390 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University of Vermont | Burlington | Vermont | 05405 | — |
| Center for Neurological Disorders | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03315130, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 27, 2022 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03315130 live on ClinicalTrials.gov.