ClinicalTrials.gov record
Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk
ClinicalTrials.gov ID: NCT03315143
Public ClinicalTrials.gov record NCT03315143. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Demonstrate the Effects of Sotagliflozin on Cardiovascular and Renal Events in Patients With Type 2 Diabetes, Cardiovascular Risk Factors and Moderately Impaired Renal Function
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the study was to compare the effect of sotagliflozin to placebo on total occurrences of cardiovascular (CV) death, hospitalization for heart failure \[HHF\], and urgent visit for heart failure \[HF\] in participants with type 2 diabetes, cardiovascular risk factors, and moderate to severely impaired renal function.
Study identification
- NCT ID
- NCT03315143
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 10,584 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 19, 2017 (Actual)
- Primary completion
- Jul 8, 2020 (Actual)
- Completion
- Jul 8, 2020 (Actual)
- Last update posted
- Oct 28, 2022
2017 – 2020
United States locations
- U.S. sites
- 119
- U.S. states
- 32
- U.S. cities
- 100
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 8400017 | Birmingham | Alabama | 35205 | — |
| Investigational Site Number 8400096 | Sheffield | Alabama | 35660 | — |
| Investigational Site Number 8400004 | Mesa | Arizona | 85206 | — |
| Investigational Site Number 8400059 | Mesa | Arizona | 85210 | — |
| Investigational Site Number 8400021 | Peoria | Arizona | 85381 | — |
| Investigational Site Number 8400014 | Surprise | Arizona | 85374 | — |
| Investigational Site Number 8400071 | Little Rock | Arkansas | 72211 | — |
| Investigational Site Number 8400039 | Beverly Hills | California | 90211 | — |
| Investigational Site Number 8400042 | Concord | California | 94520 | — |
| Investigational Site Number 8400089 | Fresno | California | 93720 | — |
| Investigational Site Number 8400006 | Huntington Park | California | 90255 | — |
| Investigational Site Number 8400036 | Long Beach | California | 90807 | — |
| Investigational Site Number 8400073 | Los Angeles | California | 90017 | — |
| Investigational Site Number 8400084 | Los Angeles | California | 90022-4302 | — |
| Investigational Site Number 8400035 | Los Gatos | California | 95032 | — |
| Investigational Site Number 8400043 | Northridge | California | 91325 | — |
| Investigational Site Number 8400025 | Sacramento | California | 95821 | — |
| Investigational Site Number 8400018 | San Dimas | California | 91713 | — |
| Investigational Site Number 8400070 | Temecula | California | 92591 | — |
| Investigational Site Number 8400013 | Waterbury | Connecticut | 06708 | — |
| Investigational Site Number 8400095 | Bradenton | Florida | 34209 | — |
| Investigational Site Number 8400090 | Clearwater | Florida | 33756 | — |
| Investigational Site Number 8400121 | Clearwater | Florida | 33756 | — |
| Investigational Site Number 8400049 | Cooper City | Florida | 33024 | — |
| Investigational Site Number 8400092 | Hialeah | Florida | 33012 | — |
| Investigational Site Number 8400026 | Hollywood | Florida | 33024 | — |
| Investigational Site Number 8400134 | Jacksonville | Florida | 32204 | — |
| Investigational Site Number 8400055 | Jacksonville | Florida | 32207-4966 | — |
| Investigational Site Number 8400056 | Jacksonville | Florida | 32216 | — |
| Investigational Site Number 8400031 | Jacksonville | Florida | 32277 | — |
| Investigational Site Number 8400037 | Maitland | Florida | 32751 | — |
| Investigational Site Number 8400078 | Miami | Florida | 33126 | — |
| Investigational Site Number 8400117 | Miami | Florida | 33135 | — |
| Investigational Site Number 8400119 | Miami | Florida | 33135 | — |
| Investigational Site Number 8400118 | Miami | Florida | 33165 | — |
| Investigational Site Number 8400105 | Miami | Florida | 33174 | — |
| Investigational Site Number 8400120 | Miami | Florida | 33176 | — |
| Investigational Site Number 8400088 | North Miami Beach | Florida | 33162 | — |
| Investigational Site Number 8400106 | Opa-locka | Florida | 33054 | — |
| Investigational Site Number 8400063 | Ormond Beach | Florida | 32174 | — |
| Investigational Site Number 8400087 | Palm Harbor | Florida | 34684-3609 | — |
| Investigational Site Number 8400108 | Spring Hill | Florida | 34609 | — |
| Investigational Site Number 8400058 | St. Petersburg | Florida | 33713 | — |
| Investigational Site Number 8400051 | Tampa | Florida | 33624 | — |
| Investigational Site Number 8400123 | Atlanta | Georgia | 30303 | — |
| Investigational Site Number 8400076 | Roswell | Georgia | 30076 | — |
| Investigational Site Number 8400033 | Honolulu | Hawaii | 96814 | — |
| Investigational Site Number 8400085 | Arlington Heights | Illinois | 60005 | — |
| Investigational Site Number 8400104 | Chicago | Illinois | 60611 | — |
| Investigational Site Number 8400027 | Chicago | Illinois | 60612 | — |
| Investigational Site Number 8400124 | Chicago | Illinois | 60612 | — |
| Investigational Site Number 8400001 | Chicago | Illinois | 60616 | — |
| Investigational Site Number 8400052 | Crystal Lake | Illinois | 60012 | — |
| Investigational Site Number 8400028 | Springfield | Illinois | 62711 | — |
| Investigational Site Number 8400125 | Michigan City | Indiana | 46360 | — |
| Investigational Site Number 8400098 | Valparaiso | Indiana | 46383 | — |
| Investigational Site Number 8400003 | Des Moines | Iowa | 50314 | — |
| Investigational Site Number 8400081 | Topeka | Kansas | 66606 | — |
| Investigational Site Number 8400041 | Louisville | Kentucky | 40213 | — |
| Investigational Site Number 8400080 | Bangor | Maine | 04401 | — |
| Investigational Site Number 8400002 | Flint | Michigan | 48504 | — |
| Investigational Site Number 8400069 | Flint | Michigan | 48532-3447 | — |
| Investigational Site Number 8400016 | Troy | Michigan | 48098 | — |
| Investigational Site Number 8400023 | Saint Cloud | Minnesota | 56303 | — |
| Investigational Site Number 8400066 | Kansas City | Missouri | 64111 | — |
| Investigational Site Number 8400024 | St Louis | Missouri | 63136 | — |
| Investigational Site Number 8400130 | Washington | Missouri | 63090 | — |
| Investigational Site Number 8400045 | Omaha | Nebraska | 68198-4100 | — |
| Investigational Site Number 8400009 | Las Vegas | Nevada | 89148 | — |
| Investigational Site Number 8400101 | Albany | New York | 12206 | — |
| Investigational Site Number 8400061 | Laurelton | New York | 11413 | — |
| Investigational Site Number 8400046 | New York | New York | 10029-6501 | — |
| Investigational Site Number 8400112 | Rosedale | New York | 11422 | — |
| Investigational Site Number 8400062 | Smithtown | New York | 11787 | — |
| Investigational Site Number 8400079 | Greenville | North Carolina | 27834-5704 | — |
| Investigational Site Number 8400020 | Morehead City | North Carolina | 28557 | — |
| Investigational Site Number 8400048 | Morehead City | North Carolina | 28557 | — |
| Investigational Site Number 8400010 | Morganton | North Carolina | 28655 | — |
| Investigational Site Number 8400072 | Fargo | North Dakota | 58103 | — |
| Investigational Site Number 8400038 | Cincinnati | Ohio | 45219 | — |
| Investigational Site Number 8400007 | Cincinnati | Ohio | 45241 | — |
| Investigational Site Number 8400015 | Columbus | Ohio | 43210 | — |
| Investigational Site Number 8400113 | Lorain | Ohio | 44053 | — |
| Investigational Site Number 8400011 | Mentor | Ohio | 44060 | — |
| Investigational Site Number 8400109 | Bend | Oregon | 97702 | — |
| Investigational Site Number 8400047 | Beaver | Pennsylvania | 15009 | — |
| Investigational Site Number 8400019 | Greensburg | Pennsylvania | 15601 | — |
| Investigational Site Number 8400097 | Indiana | Pennsylvania | 15701-3578 | — |
| Investigational Site Number 8400032 | Levittown | Pennsylvania | 19056-2404 | — |
| Investigational Site Number 8400053 | Philadelphia | Pennsylvania | 19107 | — |
| Investigational Site Number 8400012 | Pittsburgh | Pennsylvania | 15212 | — |
| Investigational Site Number 8400064 | Anderson | South Carolina | 29621 | — |
| Investigational Site Number 8400030 | Greer | South Carolina | 29651 | — |
| Investigational Site Number 8400029 | Myrtle Beach | South Carolina | 29572 | — |
| Investigational Site Number 8400040 | Memphis | Tennessee | 38163 | — |
| Investigational Site Number 8400114 | Arlington | Texas | 76015 | — |
| Investigational Site Number 8400067 | Corpus Christi | Texas | 78814 | — |
| Investigational Site Number 8400082 | Dallas | Texas | 75231 | — |
| Investigational Site Number 8400022 | El Paso | Texas | 79935 | — |
| Investigational Site Number 8400099 | Houston | Texas | 77043 | — |
| Investigational Site Number 8400103 | Houston | Texas | 77070 | — |
| Investigational Site Number 8400086 | Katy | Texas | 77450 | — |
| Investigational Site Number 8400100 | Mesquite | Texas | 75150 | — |
| Investigational Site Number 8400094 | Plano | Texas | 75093 | — |
| Investigational Site Number 8400116 | San Antonio | Texas | 78224 | — |
| Investigational Site Number 8400091 | Waco | Texas | 76710 | — |
| Investigational Site Number 8400065 | Bountiful | Utah | 84010-7717 | — |
| Investigational Site Number 8400131 | Ogden | Utah | 84405 | — |
| Investigational Site Number 8400093 | Bennington | Vermont | 05201 | — |
| Investigational Site Number 8400060 | South Burlington | Vermont | 05403 | — |
| Investigational Site Number 8400133 | Danville | Virginia | 24541-2834 | — |
| Investigational Site Number 8400054 | Fairfax | Virginia | 22039 | — |
| Investigational Site Number 8400132 | Falls Church | Virginia | 22044 | — |
| Investigational Site Number 8400034 | Manassas | Virginia | 20110 | — |
| Investigational Site Number 8400050 | Norfolk | Virginia | 23510 | — |
| Investigational Site Number 8400044 | Richmond | Virginia | 23235 | — |
| Investigational Site Number 8400111 | Richmond | Virginia | 23249 | — |
| Investigational Site Number 8400083 | Federal Way | Washington | 98003 | — |
| Investigational Site Number 8400068 | Spokane | Washington | 99207 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 635 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03315143, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 28, 2022 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03315143 live on ClinicalTrials.gov.